Circulating insulin-like growth factor (IGF)-I and IGF binding protein (IGFBP)-3 levels and postmenopausal breast cancer risk in the prostate, lung, colorectal, and ovarian cancer screening trial (PLCO) cohort [0.03%]
前列腺、肺、 colon 和卵巢癌筛查试验（PLCO）队列中循环胰岛素样生长因子(Igf)-I和igf结合蛋白(IGFBP)-3水平与绝经后乳腺癌风险的关系
Catherine Schairer,Catherine A McCarty,Claudine Isaacs et al.
Catherine Schairer et al.
Early prospective studies suggested circulating insulin-like growth factor (IGF)-I was positively associated with risk of premenopausal, but not postmenopausal, breast cancer; however, a recent, large analysis reported a statistically signi...
The relationship between hormone therapy use at the time of diagnosis of breast cancer and tumor characteristics [0.03%]
激素治疗与乳腺癌的肿瘤特性之间的关系
Mary Panjari,Robin Bell,Marijana Lijovic et al.
Mary Panjari et al.
Exposure to postmenopausal hormone therapy (HT) may affect the stage, histological type, and hormone receptor (HR) status of invasive breast cancer at the time of diagnosis. One thousand six hundred eighty-four women with newly diagnosed fi...
Comparative Study
Hormones & cancer. 2010 Apr;1(2):93-9. DOI:10.1007/s12672-010-0011-0 2010
The role of sex steroid receptors on lipogenesis in breast and prostate carcinogenesis: a viewpoint [0.03%]
性类固醇受体在乳腺和前列腺癌发生过程中促进脂质生成的作用：一个观点
Henri Rochefort,Dany Chalbos
Henri Rochefort
Cancer cells require both nutrients and mitogens to multiply and survive in the unfavorable microenvironment of solid tumors or metastases before angiogenesis. Most cancer cells do not use fatty acids (FA) from the circulation but synthesiz...
Trends in distant-stage breast, colorectal, and prostate cancer incidence rates from 1992 to 2004: potential influences of screening and hormonal factors [0.03%]
1992至2004年分期乳腺癌、结直肠癌和前列腺癌发病率的变化趋势：筛查与激素因素的潜在影响
Jean A McDougall,Christopher I Li
Jean A McDougall
Differential utilization of cancer screening between populations could lead to changes in cancer disparities. Evaluating incidence rates trends is one means of monitoring these disparities. Using Surveillance, Epidemiology, and End Results ...
Specific overexpression of cyclin E·CDK2 in early preinvasive and primary breast tumors in female ACI rats induced by estrogen [0.03%]
雌激素诱导的ACI大鼠乳腺导管原位癌和原发性肿瘤中细胞周期素E·CDK2的特异过表达
S John Weroha,Wilma L Lingle,Yan Hong et al.
S John Weroha et al.
Overexpressed Aurora A, amplified centrosomes, and aneuploidy are salient features of estrogen-induced mammary preinvasive lesions and tumors in female August--Copenhagen Irish (ACI) rats. Intimately involved in these events are cyclins and...
Quantitative immunohistochemical analysis and prognostic significance of TRPS-1, a new GATA transcription factor family member, in breast cancer [0.03%]
TRPS-1的定量免疫组化分析及其在乳腺癌预后中的意义（TRPS-1为一新GATA转录因子家族成员）
Jie Qing Chen,Jennifer Litton,Li Xiao et al.
Jie Qing Chen et al.
The trichorhinophalangeal syndrome 1 (TRPS-1) gene is a novel GATA transcription factor family member. Previously, using a gene expression profiling and immunohistochemistry (IHC) screen, we identified TRPS-1 as a highly prevalent gene in b...
Estrogen-induced aurora kinase-A (AURKA) gene expression is activated by GATA-3 in estrogen receptor-positive breast cancer cells [0.03%]
雌激素通过GATA-3激活阳性乳腺癌细胞中的Aurora激酶-A(AURKA)基因表达
Shoulei Jiang,Hiroshi Katayama,Jin Wang et al.
Shoulei Jiang et al.
Aurora-A is a proto-oncogenic mitotic kinase that is frequently overexpressed in human epithelial malignancies including in breast and ovarian cancers. The mechanism of transcriptional upregulation of Aurora-A in human breast cancer is not ...
Susan E Hankinson,A Heather Eliassen
Susan E Hankinson
Evidence from both laboratory and epidemiologic studies indicate a key role of hormones in the etiology of breast cancer. In epidemiologic studies, indirect data, including the consistent associations observed between reproductive factors a...
Letter from the editor-in-chief [0.03%]
主编来信
Jonathan J Li
Jonathan J Li
Role for microRNAs in regulating glucocorticoid response and resistance in multiple myeloma [0.03%]
微小核糖核酸在调节多发性骨髓瘤糖皮质激素反应和耐药中的作用
Michael A Tessel,Ashley L Benham,Nancy L Krett et al.
Michael A Tessel et al.
Glucocorticoids (GCs) are widely used in the treatment of hematological malignancies such as multiple myeloma. However, the development of resistance to GCs limits their clinical utility. Response to GCs is dependent on an active glucocorti...