Welcome from the new Discover Oncology journal : Editorial - 28th December, 2020 [0.03%]
来自新出刊的Discover Oncology期刊的迎新春编辑评论-2020年12月28日
Eleonora Candi
Eleonora Candi
Prevalence of Histological Characteristics of Breast Cancer in Rwanda in Relation to Age and Tumor Stages [0.03%]
卢旺达乳腺癌组织学特征的流行率与年龄和肿瘤分期的关系
Jeanne P Uyisenga,Yvan Butera,Ahmed Debit et al.
Jeanne P Uyisenga et al.
Breast cancer is a complex disease, and it is the most common cause of morbidity and mortality among women worldwide. In Sub-Saharan Africa, the clinical characteristics and tumor profiles of breast cancer are still unknown. In the present ...
Outcome of Clinical Genetic Testing in Patients with Features Suggestive for Hereditary Predisposition to PTH-Mediated Hypercalcemia [0.03%]
具有遗传性PTH介导的高钙血症易感特征的患者临床基因检测结果分析
Shafaq Khairi,Jenae Osborne,Michelle F Jacobs et al.
Shafaq Khairi et al.
Primary hyperparathyroidism (pHPT) is associated with familial syndromes such as multiple endocrine neoplasia type 1 (MEN1), 2A (MEN2A), MEN-like syndromes (CDKN1B), and CDC73-related disorder (hyperparathyroidism - jaw tumor syndrome (HPJT...
Nuclear PDCD4 Expression Defines a Subset of Luminal B-Like Breast Cancers with Good Prognosis [0.03%]
核PDCD4表达定义了一组预后良好的 luminal B样乳腺癌亚型
Santiago Madera,María F Chervo,Violeta A Chiauzzi et al.
Santiago Madera et al.
The hormone receptor-positive (estrogen and/or progesterone receptor (PR)-positive) and HER2-negative breast cancer (BC) subtype is a biologically heterogeneous entity that includes luminal A-like (LumA-like) and luminal B-like (LumB-like) ...
Intrinsic and Extrinsic Factors Governing the Transcriptional Regulation of ESR1 [0.03%]
ESR1转录调控的内在和外在因素
David K Lung,Rebecca M Reese,Elaine T Alarid
David K Lung
Transcriptional regulation of ESR1, the gene that encodes for estrogen receptor α (ER), is critical for regulating the downstream effects of the estrogen signaling pathway in breast cancer such as cell growth. ESR1 is a large and complex g...
Interleukin-23 Represses the Level of Cell Senescence Induced by the Androgen Receptor Antagonists Enzalutamide and Darolutamide in Castration-Resistant Prostate Cancer Cells [0.03%]
白细胞介素23通过抑制雄激素受体拮抗剂恩扎卢胺和达洛鲁胺诱导的衰老水平来促进去势抵抗性前列腺癌细胞增殖
Siddharth Gupta,Thanakorn Pungsrinont,Ondrej Ženata et al.
Siddharth Gupta et al.
Prostate cancer (PCa) is the most common cancer and the second leading cause of cancer-related deaths of men in Western countries. Androgen deprivation therapy is initially successful, however eventually fails, and tumors progress to the mo...
Epithelial Mesenchymal Transition and Progression of Breast Cancer Promoted by Diabetes Mellitus in Mice Are Associated with Increased Expression of Glycolytic and Proteolytic Enzymes [0.03%]
糖尿病通过增加糖酵解和蛋白水解相关酶的表达促进小鼠乳腺上皮间充质转化及乳腺癌进展
Rubí Viedma-Rodríguez,María Guadalupe Martínez-Hernández,Dante Israel Martínez-Torres et al.
Rubí Viedma-Rodríguez et al.
The development of breast cancer (BC) is influenced by age, overweight, obesity, metabolic syndrome, and diabetes mellitus (DM), which are associated with hyperglycemia, glucose intolerance, insulin resistance, and oxidative stress. High gl...
The Thyroid Tumor Microenvironment: Potential Targets for Therapeutic Intervention and Prognostication [0.03%]
甲状腺肿瘤微环境：治疗干预和预后的潜在靶点
Laura MacDonald,Jonathan Jenkins,Grace Purvis et al.
Laura MacDonald et al.
Thyroid cancer is the most common endocrine malignancy and incidences are rising rapidly, in both pediatric and adult populations. Many thyroid tumors are successfully treated which results in low mortality rates, but there is often a signi...
Estrogen Receptor Positive and Progesterone Receptor Negative Breast Cancer: the Role of Hormone Therapy [0.03%]
雌激素受体阳性而黄体酮受体阴性的乳腺癌：激素疗法的作用
Robert Dembinski,Vishnu Prasath,Carisa Bohnak et al.
Robert Dembinski et al.
ER+/PR- (estrogen receptor positive and progesterone receptor negative) tumors constitute only a small portion of the breast cancer population. Patients with ER+/PR- tumors, however, are characterized by worse survival compared to patients ...
Heterogeneous Associations Between Obesity and Reproductive-Related Factors and Specific Breast Cancer Subtypes Among Hong Kong Chinese Women [0.03%]
肥胖和生殖相关因素与香港女性特定亚型乳腺癌的异质性关联研究
Priscilla Ming Yi Lee,Chi Hei Kwok,Wing Cheong Chan et al.
Priscilla Ming Yi Lee et al.
Previous studies reported heterogeneous associations between obesity and reproductive-related breast cancer risk factors and breast cancer intrinsic subtypes; however, few studies have been conducted in Asian populations. Here, we aimed to ...