Hypothesis: epigenetic effects will require a review of the genetics of child development [0.03%]
假设：表观遗传效应需要对儿童发展遗传学进行重新审查
György Kosztolányi
György Kosztolányi
The worldwide prevalence of developmental disorders in children including birth defects, mental dysfunctions, as well as early-life abnormalities leading to the predisposition for adult diseases is one of the major unsolved problems in medi...
The impact of single gene and chromosomal disorders on hospital admissions in an adult population [0.03%]
单基因及染色体异常对成人住院影响的研究
Danielle E Dye,Kate J Brameld,Susannah Maxwell et al.
Danielle E Dye et al.
Although the role of single gene and chromosomal disorders in pediatric illness has been recognized since the 1970s, there are few data describing the impact of these often severe disorders on the health of the adult population. In this stu...
A holistic approach to education programs in thalassemia for a multi-ethnic population: consideration of perspectives, attitudes, and perceived needs [0.03%]
地中海贫血教育项目的整体性方法：多民族人群的地中海贫血教育项目：考虑视角、态度和需求感知
Li Ping Wong,Elizabeth George,Jin-Ai Mary Anne Tan
Li Ping Wong
Hemoglobin disorders which include thalassemias are the most common heritable disorders. Effective treatment is available, and these disorders can be avoided as identification of carriers is achievable using simple hematological tests. An i...
Genetic testing for familial/hereditary breast cancer-comparison of guidelines and recommendations from the UK, France, the Netherlands and Germany [0.03%]
家族性/遗传性乳腺癌的基因检测-英国、法国、荷兰和德国指南和建议的比较
Dorothea Gadzicki,D Gareth Evans,Hilary Harris et al.
Dorothea Gadzicki et al.
In this review, the national guidelines and recommendations for genetic testing for familial/hereditary breast cancer from the UK, France, the Netherlands and Germany were evaluated as to the inclusion criteria for genetic testing. In all f...
Gwendolyn P Quinn,Jessica Q McIntyre,Susan T Vadaparampil
Gwendolyn P Quinn
Hispanic women often have low participation rates in cancer genetics research. Additionally, Hispanic sub-ethnicities may have varying accrual rates based on unique cultural factors. Hispanic women were recruited through flyers placed in th...
Genetic testing and counseling for hereditary neurological diseases in Mali [0.03%]
马里的遗传性神经疾病基因检测和咨询
Katherine Gloria Meilleur,Souleymane Coulibaly,Moussa Traoré et al.
Katherine Gloria Meilleur et al.
As genetic advances become incorporated into health care delivery, disparities between developing and developed countries may become greater. By addressing genetic health care needs and specific differences of developing countries, these di...
Frequency distribution of the single-nucleotide -108C/T polymorphism at the promoter region of the PON1 gene in Asian Indians and its relationship with coronary artery disease [0.03%]
亚洲印度人PON1基因启动区-108C/T单核苷酸多态性的频度分布及其与冠心病的关系
Imteyaz Ahmad,Rajiv Narang,Anand Venkatraman et al.
Imteyaz Ahmad et al.
A single-nucleotide promoter region polymorphism (-108C/T) of the paraoxonase (PON1) gene had been suggested to influence an individual's susceptibility to coronary artery disease (CAD). No data is available on this polymorphism from India....
Factors influencing consultation to discuss family history of cancer by asymptomatic patients in primary care [0.03%]
初级保健中无症状患者讨论家族癌症史咨询的影响因素
Jennifer N W Lim,Jenny Hewison,Carol E Chu et al.
Jennifer N W Lim et al.
Patient self-initiated consultations to discuss family history of cancer in primary care and the factors leading to these consultations have not been investigated. Seventy-one out of 150 asymptomatic patients with a family history of cancer...
Frequency of sickle cell genotype among the Yorubas in Lagos: implications for the level of awareness and genetic counseling for sickle cell disease in Nigeria [0.03%]
尼日利亚拉各斯约鲁巴人中镰状细胞基因型的频率及其对镰状细胞疾病意识水平和遗传咨询的意义
Idowu A Taiwo,Olufemi A Oloyede,Ade O Dosumu
Idowu A Taiwo
The frequency of sickle cell genotype (HbSHbS) among the Yorubas living in Lagos, Nigeria, was determined. Seven hundred fifteen (715) subjects of different age groups took part in the study after filling consent forms and questionnaires. T...
Confidence of primary care physicians in their ability to carry out basic medical genetic tasks-a European survey in five countries-Part 1 [0.03%]
五国欧洲国家全科医师基本医学遗传能力信心调查-第一部分
Irmgard Nippert,Hilary J Harris,Claire Julian-Reynier et al.
Irmgard Nippert et al.
Western health care systems are facing today increasing movement of genetic knowledge from research labs into clinical practice. This paper reports the results of a survey that addressed the confidence of primary care physicians in their ab...