Curtis Benson,Bradley J Kerr
Curtis Benson
There is a high prevalence of pain, depression, and cognitive dysfunction in patients with Multiple Sclerosis (MS). These symptoms affect daily tasks resulting in a significant reduction in quality of life. Pain and cognitive changes have b...
Michael H Stone
Michael H Stone
Borderline Personality Disorder (BPD) has been defined as a personality disorder in all editions of DSM since 1980; namely, DSM III through V. The criteria are a mixture of symptoms and traits; the etiology, a heterogeneous array of genetic...
Weredeselam M Olango,David P Finn
Weredeselam M Olango
The intensity and severity of perceived pain does not correlate consistently with the degree of peripheral or central nervous system tissue damage or with the intensity of primary afferent or spinal nociceptive neurone activity. In this res...
Does the goal justify the methods? Harm and benefit in neuroscience research using animals [0.03%]
目的值得手段吗？使用动物开展神经科学研究中的利与弊
Ana Catarina Vieira de Castro,I Anna S Olsson
Ana Catarina Vieira de Castro
The goal of the present chapter is to open up for discussion some of the major ethical issues involved in animal-based neuroscience research. We begin by approaching the question of the moral acceptability of the use of animals in research ...
Vladyslav V Vyazovskiy,Ugo Faraguna
Vladyslav V Vyazovskiy
In the last decades a substantial knowledge about sleep mechanisms has been accumulated. However, the function of sleep still remains elusive. The difficulty with unraveling sleep's function may arise from the lack of understanding of how t...
Tim Outhred,Andrew H Kemp,Gin S Malhi
Tim Outhred
Bipolar spectrum disorders (BSDs) are associated with great personal and socioeconomic burden, with patients often facing a delay in detection, misdiagnosis when detected, and a trial-and-error approach to finding the most appropriate treat...
Sensory, hormonal, and neural basis of maternal aggression in rodents [0.03%]
啮齿动物母性攻击行为的感受、激素和神经学基础
Rosa Maria Martins de Almeida,Annabel Ferreira,Daniella Agrati
Rosa Maria Martins de Almeida
We review existing knowledge of the neural, hormonal, and sensory basis of maternal aggression in the female rat. Although females may express different kinds of aggression, such as defense or dominance, the most frequent and conspicuous fo...
Anke Van der Perren,Chris Van den Haute,Veerle Baekelandt
Anke Van der Perren
In order to study the molecular pathways of Parkinson's disease (PD) and to develop novel therapeutic strategies, scientific investigators rely on animal models. The identification of PD-associated genes has led to the development of geneti...
Neurobehavioral Mechanisms of Traumatic Stress in Post-traumatic Stress Disorder [0.03%]
创伤后应激障碍的创伤性压力神经行为机制研究进展
M Danet Lapiz-Bluhm,Alan L Peterson
M Danet Lapiz-Bluhm
Post-traumatic stress disorder (PTSD) is a debilitating psychiatric disorder that develops following trauma exposure. It is characterized by four symptom clusters: intrusion, avoidance, negative alteration in cognitions and mood, and altera...
Melissa J Green,Leah Girshkin,Nina Teroganova et al.
Melissa J Green et al.
The role of stress in precipitating psychotic episodes in schizophrenia and bipolar disorder has long been acknowledged. However, the neurobiological mechanism/s of this association have remained elusive. Current neurodevelopmental models o...