The Impact of Early Life Experiences on Stress Neurobiology and the Development of Anxiety [0.03%]
早期生活经历对压力神经生物学以及焦虑发展的影响
Yanbin Niu,M Catalina Camacho,Shuang Wu et al.
Yanbin Niu et al.
We examine the association between stress exposure during early development (i.e., the prenatal period through the first two postnatal years) and variation in brain structure and function relevant to anxiety. Evidence of stress-related effe...
Christopher Poppe,Dimitris Repantis
Christopher Poppe
In this chapter, we provide an overview of ethical aspects of psychedelic-assisted treatments in the areas of clinical ethics, research ethics, and at the intersection of psychedelic medicine and society. In contrast to earlier psychedelic ...
E Leighton Durham,Antonia N Kaczkurkin
E Leighton Durham
Anxiety and related disorders are prevalent across the lifespan, often have their onset during youth, and are associated with notable levels of impairment and burden across multiple domains. Elucidating the associations between differential...
Katelyn I Oliver,Dasani DelRosario,Jennifer S Stevens
Katelyn I Oliver
Although women are diagnosed with anxiety and stress-related disorders at twice the rate of men, there remains a lack of clarity around how to enhance treatment within each sex to reduce disparate rates of anxiety. However, in recent years,...
What Can We Learn About Alzheimer's Disease from People with Down Syndrome? [0.03%]
唐氏综合症患者能教会我们哪些阿尔茨海默病的教训？
Lucia Maure-Blesa,Iñigo Rodríguez-Baz,Maria Carmona-Iragui et al.
Lucia Maure-Blesa et al.
Down syndrome (DS) is the most frequent cause of intellectual disability of genetic origin, estimated to affect about 1 in 700 babies born worldwide (CDC 2023). In Europe and the United States, current estimates indicate a population preval...
Alessandro Chioino,Carmen Sandi
Alessandro Chioino
The functional complexity of brain circuits underlies the broad spectrum of behaviors, cognitive functions, and their associated disorders. Mitochondria, traditionally known for their role in cellular energy metabolism, are increasingly rec...
Transcranial Magnetic Stimulation for Posttraumatic Stress Disorder and Generalized Anxiety Disorder [0.03%]
经颅磁刺激技术治疗创伤后应激障碍和广泛性焦虑障碍的研究进展
Samantha L Cilli,Miriam A Goldberg,Camila Cosmo et al.
Samantha L Cilli et al.
Posttraumatic stress disorder (PTSD) and generalized anxiety disorder (GAD) are debilitating psychiatric disorders. While treatments are often effective, many patients do not adequately respond or experience significant side effects. Transc...
Jawza A Almutairi,Emma J Kidd
Jawza A Almutairi
Alzheimer's disease is a highly complex and multifactorial neurodegenerative disorder, with age being the most significant risk factor. The incidence of Alzheimer's disease doubles every 5 years after the age of 65. Consequently, one of the...
Abigail A Testo,Gwenyth Roundy,Julie A Dumas
Abigail A Testo
Deficits in memory, language, and other cognitive domains that impact an individual's ability to perform necessary tasks of daily living are symptoms of dementia, which is a major cause of death and disability in older adults. As the global...
Chiara Caporuscio,Sascha Benjamin Fink
Chiara Caporuscio
Belief change is crucial to therapeutic benefit in psychedelic-assisted therapy as well as in more traditional forms of therapy. However, the use of psychedelics comes with a few unique challenges that require extra caution. First, drastic ...