The Role of Cannabinoids and the Endocannabinoid System in the Treatment and Regulation of Nausea and Vomiting [0.03%]
cannabinoids和内源性 cannabinoid系统在恶心呕吐治疗和调节中的作用
Erin M Rock,Linda A Parker
Erin M Rock
Despite using the recommended anti-emetic treatments, control of nausea and vomiting is still an unmet need for cancer patients undergoing chemotherapy treatment. Few properly controlled clinical trials have evaluated the potential of exoge...
Insights into the Neurobiology of Behavioral Inhibition from Nonhuman Primate Models [0.03%]
非人灵长类模型的行为抑制神经生物学见解
Lillian J Campos,Carly M Drzewiecki,Andrew S Fox
Lillian J Campos
Children with extreme behavioral inhibition (BI) are at a significantly greater risk to develop anxiety disorders later in life. We and others have identified similar early-life temperamental BI in nonhuman primates (NHPs), including rhesus...
Emotion Regulation Under Stress: A Social Processing and Memory Perspective [0.03%]
压力下的情绪调节：社会处理与记忆视角
Nicholas J Dennis,Tasha Bulgin,Casey M Nicastri et al.
Nicholas J Dennis et al.
Research on emotion regulation often focuses on cognitively effortful self-regulation strategies, but exposure to stress has been shown to interfere with the underlying mechanisms supporting such processes. Understanding alternative strateg...
Ko-Ping Chou,Ryan Smith
Ko-Ping Chou
The drive to seek information through exploratory behavior is widespread in both humans and other animals. This can be adaptive in reducing uncertainty about the best course of action within novel or changing environments. However, explorat...
Krisztina Monory,Inigo Ruiz de Azua,Beat Lutz
Krisztina Monory
During the past 30 years, the endocannabinoid system (ECS) has emerged as a major signalling system in the mammalian brain regulating neurotransmission in numerous brain regions and in various cell populations. Endocannabinoids are able to ...
Fear and Anxiety in Schizophrenia: A Focus on Development, Assessment, and Mechanisms [0.03%]
精神分裂症中的恐惧和焦虑：关注发展、评估和机制
Brandee Feola,Marren Jenkins,Julia M Sheffield et al.
Brandee Feola et al.
In people with schizophrenia, anxiety is highly prevalent and related to numerous negative outcomes; unfortunately, anxiety is both underreported and understudied in schizophrenia. The current review highlights the importance and utility of...
Dana E Díaz,Hannah C Becker,Kate D Fitzgerald
Dana E Díaz
Pediatric anxiety disorders and post-traumatic stress disorder (PTSD) are associated with elevated threat sensitivity and impaired emotion regulation, accompanied by dysfunction in the neural circuits involved in these processes. Despite es...
Fears Worth Testing Out: A Systematic Review of the Neural Mechanisms of Treatment Outcome for Anxiety-Related Disorders [0.03%]
值得检验的恐惧：焦虑相关障碍治疗结局的神经机制系统综述
Robin Aupperle,Hannah Berg,Jacob Armstrong
Robin Aupperle
With the advent of human neuroimaging, researchers were drawn to the idea that by better understanding the human brain, more effective mental health interventions could be developed. It has been more than 20 years since the first functional...
Alisa R Zoltowski,Caitlin A Convery,Ekomobong Eyoh et al.
Alisa R Zoltowski et al.
In this article, we briefly overview how the expression, measurement, and treatment of anxiety in autism may be different from the general population. We review the literature on links between sensory processing differences and anxiety, whi...
Achieving Inclusion in Pharmacological Clinical Trials for Alzheimer's Disease [0.03%]
阿尔茨海默病药理临床试验的包容性实现
Doris Molina-Henry,Rema Raman
Doris Molina-Henry
Participant recruitment and retention into randomized controlled trials (RCTs) is a growing and evolving science. It varies dramatically by discipline given the important and key choices that must be made based on the unique trial design co...