Validation of the Food Safe Zone questionnaire for families of individuals with Prader-Willi syndrome [0.03%]
普瑞德威利综合征患者家庭的食品安全问卷调查的有效性评估
Elisabeth M Dykens,Elizabeth Roof,Hailee Hunt-Hawkins et al.
Elisabeth M Dykens et al.
Background: Prader-Willi syndrome (PWS), a genetic neurodevelopmental disorder, is characterized by hyperphagia and significant behavioral problems. Hyperphagic individuals with PWS are chronically hungry yet rarely feel ...
Regional hippocampal thinning and gyrification abnormalities and associated cognition in children with prenatal alcohol exposure [0.03%]
孕期酒精暴露儿童的区域海马变薄和回旋异常及相应的认知功能损伤
Blake A Gimbel,Jeffrey R Wozniak,Bryon A Mueller et al.
Blake A Gimbel et al.
Background: Prenatal alcohol exposure (PAE) impacts hippocampal structure and function, contributing to deficits in memory and decision-making in affected individuals. Here, we evaluate hippocampal anomalies in children w...
Reduced white matter integrity and disrupted brain network in children with type 2 and 3 spinal muscular atrophy [0.03%]
脊髓性肌萎缩类型二和三患儿的低白质完整性和脑网络连接异常
Huirong Nie,Shasha Lan,Huan Wang et al.
Huirong Nie et al.
Background: Spinal muscular atrophy (SMA) is caused by reduced expression of survival motor neuron (SMN) protein. Previous studies indicated SMA causes not only lower motor neuron degeneration but also extensive brain inv...
A randomized, placebo-controlled, cross-over trial of ketamine in Rett syndrome [0.03%]
雷特综合征患者的氯胺酮随机、安慰剂对照交叉试验
Kathleen Campbell,Jeffrey L Neul,David N Lieberman et al.
Kathleen Campbell et al.
Background: Preclinical studies and anecdotal case reports support the potential therapeutic benefit of low-dose oral ketamine as a treatment of clinical symptoms in Rett syndrome (RTT); however, no controlled studies hav...
Randomized Controlled Trial
Journal of neurodevelopmental disorders. 2025 Jan 24;17(1):4. DOI:10.1186/s11689-025-09591-y 2025
Resting state EEG in young children with Tuberous Sclerosis Complex: associations with medications and seizures [0.03%]
结节性硬化症儿童静息态脑电图特征及其与癫痫发作和用药的关系探究
Caitlin C Clements,Anne-Michelle Engelstad,Carol L Wilkinson et al.
Caitlin C Clements et al.
Background: Tuberous Sclerosis Complex (TSC) is a rare genetic condition caused by mutation to TSC1 or TSC2 genes, with a population prevalence of 1/7000 births. TSC manifests behaviorally with features of autism, epileps...
Acute administration of NLX-101, a Serotonin 1A receptor agonist, improves auditory temporal processing during development in a mouse model of Fragile X Syndrome [0.03%]
NLX-101（一种血清素1A受体激动剂）急性给药可改善脆性X综合征小鼠模型在发育过程中的听觉时间处理能力
Xin Tao,Katilynne Croom,Adrian Newman-Tancredi et al.
Xin Tao et al.
Background: Fragile X syndrome (FXS) is a leading known genetic cause of intellectual disability and autism spectrum disorders (ASD)-associated behaviors. A consistent and debilitating phenotype of FXS is auditory hyperse...
Objective approach to diagnosing attention deficit hyperactivity disorder by using pixel subtraction and machine learning classification of outpatient consultation videos [0.03%]
基于像素减法和机器学习分类的注意缺陷多动障碍门诊视频诊断客观方法研究
Yi-Hung Chiu,Ying-Han Lee,San-Yuan Wang et al.
Yi-Hung Chiu et al.
Background: Attention deficit hyperactivity disorder (ADHD) is a common childhood neurodevelopmental disorder, affecting between 5% and 7% of school-age children. ADHD is typically characterized by persistent patterns of ...
Brain volumes, cognitive, and adaptive skills in school-age children with Down syndrome [0.03%]
唐氏综合征学龄期儿童脑容量、认知和适应能力
Rebecca Grzadzinski,Kattia Mata,Ambika S Bhatt et al.
Rebecca Grzadzinski et al.
Background: Down syndrome (DS) is the most common congenital neurodevelopmental disorder, present in about 1 in every 700 live births. Despite its prevalence, literature exploring the neurobiology underlying DS and how th...
Effects of elastic therapeutic taping on reducing drooling in children with neurological disorders: a systematic review of randomized controlled trials [0.03%]
弹性运动贴扎减少神经发育障碍儿童流涎的系统评价
Krystal Tsz Ting Lam,Alex Tsz Wai Hung,Kendy Lau et al.
Krystal Tsz Ting Lam et al.
Background & aims: Effective treatment for anterior drooling in children with neurological disorders can lead to improved social interactions, reduced physical complications such as perioral infections, and enhanced quali...
Specialization of the brain for language in children with Fragile X Syndrome: a functional Near Infrared Spectroscopy study [0.03%]
脆性X综合征儿童的语言脑区 specialization: 近红外光谱功能成像研究
Elizabeth Smith,Kelli C Dominick,Lauren M Schmitt et al.
Elizabeth Smith et al.
Specialization of the brain for language is early emerging and essential for language learning in young children. Fragile X Syndrome (FXS) is a neurogenetic disorder marked by high rates of delays in both expressive and receptive language, ...