A neural substrate for sensory over-responsivity defined by exogenous and endogenous brain systems [0.03%]
由外源性和内源性脑系统定义的感觉过敏感神经基质
Hannah L Choi,Maia C Lazerwitz,Rachel Powers et al.
Hannah L Choi et al.
Background: Exogenous (outward-directed) and endogenous (inward-directed) neural systems are essential for cognition and behavior. However, how they are altered in neurodiverse (ND) children remains unanswered in part due...
Long-term safety and tolerability of transdermal cannabidiol gel in children and adolescents with Fragile X syndrome (ZYN2-CL-017): an interim analysis of an ongoing open-label extension study [0.03%]
儿童和青少年脆弱X综合征长期使用透皮给药CBD凝胶的长期安全性和耐受性（ZYN2-CL-017）：一项正在进行的开放标签扩展研究的中期分析
Elizabeth Berry-Kravis,Randi Hagerman,Jonathan Cohen et al.
Elizabeth Berry-Kravis et al.
Background: Dysregulated endocannabinoid signaling is involved in Fragile X syndrome (FXS), suggesting a potential role for the endocannabinoid signaling modulator, cannabidiol, in treatment. ZYN002 is a synthetic cannabi...
Randomized Controlled Trial
Journal of neurodevelopmental disorders. 2025 Nov 18;17(1):69. DOI:10.1186/s11689-025-09657-x 2025
Sex-specific and age-related progression of auditory neurophysiological deficits in the Cln3 mouse model of Batten disease [0.03%]
Cln3型Batten病小鼠模型中听觉神经生理缺陷的性别特异性及年龄相关性进展
Yanya Ding,Jingyu Feng,Viollandi Prifti et al.
Yanya Ding et al.
Background: CLN3 disease, also known as juvenile Batten disease, is a recessively inherited neurodevelopmental disorder caused by mutations in the CLN3 gene. It represents the most common form of Neuronal Ceroid Lipofusci...
The effectiveness of transcranial electrical stimulation in individuals with specific learning disorder (SLD): systematic review and transfer analysis [0.03%]
经颅电刺激在特定学习障碍（SLD）患者中的有效性：系统评价和转换分析
Vahid Nejati,Fateme Ghafuri,Katayoon Hosseini et al.
Vahid Nejati et al.
This comprehensive review aimed to investigate the transferability of transcranial electrical Stimulation (tES) interventions in individuals with specific learning disabilities (SLD) based on the FIELD model, encompassing function, implemen...
Development of the Angelman syndrome video assessment: quantifying meaningful change [0.03%]
天使人综合症视频评估的发展：量化有意义的变化
Kriszha A Sheehy,Mindy G Leffler,Rebecca J Woods et al.
Kriszha A Sheehy et al.
Background: The Angelman Syndrome Video Assessment (ASVA) is a clinician-reported outcome measure that was developed to assess the functional ability of individuals with Angelman Syndrome (AS) in a familiar environment. T...
Longitudinal characterization of clinical, developmental, and behavioral phenotypes in 101 children and adults with FOXG1 syndrome [0.03%]
FOXG1综合征的临床、发育和行为表型的纵向特征（101名儿童及成人）
Elise Brimble,Pam Ventola,Elizabeth Blomenberg et al.
Elise Brimble et al.
Background: FOXG1 syndrome is a severe genetic neurodevelopmental disorder characterized by intellectual and developmental disabilities (IDD), postnatal microcephaly, epilepsy, and movement disorder. With the advent of mo...
Functional connectivity patterns differ as a function of co-occurring attentional problems in preschoolers with autism [0.03%]
学龄前自闭症儿童的注意缺陷与功能连接模式的关系
Alex Boxberger,Bosi Chen,Lindsay Olson et al.
Alex Boxberger et al.
Background: Symptoms of attention-deficit/hyperactivity disorder (ADHD) are common in children with autism spectrum disorder (ASD), and are associated with greater developmental challenges, poorer clinical outcomes, and a...
Evidence of neurocognitive and resting state functional connectivity differences in carriers of NRXN1 deletions [0.03%]
NRXN1缺失携带者的神经认知和静息态功能连接差异证据
Jacqueline Fitzgerald,Ciara J Molloy,Thomas Dinneen et al.
Jacqueline Fitzgerald et al.
Background: NRXN1 deletion (NRXN1 del) is a rare copy number variant associated with several neurodevelopmental, neuropsychiatric, and cognitive outcomes. The NRXN1 gene encodes for a pre-synaptic cell adhesion molecule t...
Clinical determinants of psychiatric care in genetic neurodevelopmental disorders: a cross-sectional analysis [0.03%]
遗传性神经发育障碍的精神病护理临床决定因素：横断面分析
David J Adams,Alexandra M Klomhaus,Nicole R Wong et al.
David J Adams et al.
Jessica Martin,Alkistis Mavrogalou-Foti,Josefine Eck et al.
Jessica Martin et al.
Background: Pathogenic CASK variants are associated with neurodevelopmental disorders of variable severity including X-linked intellectual disability (XLID) and microcephaly with pontocerebellar hypoplasia (MICPCH). Altho...