Intrapartum exposure to synthetic oxytocin, maternal BMI, and neurodevelopmental outcomes in children within the ECHO consortium [0.03%]
产时合成缩宫素暴露、产妇体重指数与ECHO研究联盟中儿童神经发育结局的关系
Lisa Kurth,T Michael O&#x;Shea,Irina Burd et al.
Lisa Kurth et al.
Background: Synthetic oxytocin (sOT) is frequently administered during parturition. Studies have raised concerns that fetal exposure to sOT may be associated with altered brain development and risk of neurodevelopmental d...
Rescue of impaired blood-brain barrier in tuberous sclerosis complex patient derived neurovascular unit [0.03%]
TSC患者来源的神经血管单元中血脑屏障损伤的修复
Jacquelyn A Brown,Shannon L Faley,Monika Judge et al.
Jacquelyn A Brown et al.
Background: Tuberous sclerosis complex (TSC) is a multi-system genetic disease that causes benign tumors in the brain and other vital organs. The most debilitating symptoms result from involvement of the central nervous s...
Clinical, genetic, and cognitive correlates of seizure occurrences in Phelan-McDermid syndrome [0.03%]
临床、遗传及认知特征与Phelan-McDermid综合征患者癫痫发作的相关性研究
Tess Levy,Jacob Gluckman,Paige M Siper et al.
Tess Levy et al.
Background: Phelan-McDermid syndrome (PMS) is a genetic neurodevelopmental disorder caused by SHANK3 haploinsufficiency and is associated with an increased risk for seizures. Previous literature indicates that around one ...
Reduced lateralization of multiple functional brain networks in autistic males [0.03%]
自闭症男性多项功能脑网络侧化程度下降
Madeline Peterson,Molly B D Prigge,Dorothea L Floris et al.
Madeline Peterson et al.
Background: Autism spectrum disorder has been linked to a variety of organizational and developmental deviations in the brain. One such organizational difference involves hemispheric lateralization, which may be localized...
Sex differences during development in cortical temporal processing and event related potentials in wild-type and fragile X syndrome model mice [0.03%]
野生型和脆性X综合症模型小鼠在发育过程中皮质时间处理及事件相关电位的性别差异
Katilynne Croom,Jeffrey A Rumschlag,Michael A Erickson et al.
Katilynne Croom et al.
Background: Autism spectrum disorder (ASD) is currently diagnosed in approximately 1 in 44 children in the United States, based on a wide array of symptoms, including sensory dysfunction and abnormal language development....
Behavioral changes in patients with Prader-Willi syndrome receiving diazoxide choline extended-release tablets compared to the PATH for PWS natural history study [0.03%]
与PATH自然史研究中的普拉德-威利综合征患者相比使用氯化丁苯酞缓释片的普拉德-威利综合征患者的的行为变化
Theresa V Strong,Jennifer L Miller,Shawn E McCandless et al.
Theresa V Strong et al.
Background: Prader-Willi syndrome (PWS) is a rare neurobehavioral-metabolic disease caused by the lack of paternally expressed genes in the chromosome 15q11-q13 region, characterized by hypotonia, neurocognitive problems,...
Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder [0.03%]
天门冬氨酸琥珀酸转氨酶缺乏的自然史研究临床及分子结局分析：一种模型代谢神经发育障碍
Itay Tokatly Latzer,Jean-Baptiste Roullet,Wardiya Afshar-Saber et al.
Itay Tokatly Latzer et al.
Background: Succinic semialdehyde dehydrogenase deficiency (SSADHD) represents a model neurometabolic disease at the fulcrum of translational research within the Boston Children's Hospital Intellectual and Developmental D...
An overview of current advances in perinatal alcohol exposure and pathogenesis of fetal alcohol spectrum disorders [0.03%]
孕期酒精暴露与胎儿酒精谱系障碍发病机制的现状及进展概述
Xingdong Zeng,Yongle Cai,Mengyan Wu et al.
Xingdong Zeng et al.
The adverse use of alcohol is a serious global public health problem. Maternal alcohol consumption during pregnancy usually causes prenatal alcohol exposure (PAE) in the developing fetus, leading to a spectrum of disorders known as fetal al...
Exploring an objective measure of overactivity in children with rare genetic syndromes [0.03%]
探究罕见遗传综合征儿童客观过度活跃措施
Rory O&#x;Sullivan,Stacey Bissell,Georgie Agar et al.
Rory O&#x;Sullivan et al.
Background: Overactivity is prevalent in several rare genetic neurodevelopmental syndromes, including Smith-Magenis syndrome, Angelman syndrome, and tuberous sclerosis complex, although has been predominantly assessed usi...
Neurobehavioral outcomes of neonatal asymptomatic congenital cytomegalovirus infection at 12-months [0.03%]
先天性巨细胞病毒感染新生儿的神经行为结果（12个月时无症状婴儿）
Sally M Stoyell,Jed T Elison,Emily Graupmann et al.
Sally M Stoyell et al.
Background: Congenital cytomegalovirus (cCMV) is the most common congenital viral infection in the United States. Symptomatic infections can cause severe hearing loss and neurological disability, although ~ 90% of cCMV in...