Alejandro Chamorro-Garcia,Arben Merkoçi
Alejandro Chamorro-Garcia
Medical diagnosis has been greatly improved thanks to the development of new techniques capable of performing very sensitive detection and quantifying certain parameters. These parameters can be correlated with the presence of specific mole...
Gunjan Bisht,Sagar Rayamajhi
Gunjan Bisht
Nanoparticles, with their selective targeting capabilities and superior efficacy, are becoming increasingly important in modern cancer therapy and starting to overshadow traditional cancer therapies such as chemotherapy radiation and surger...
Bioavailability of Orally Delivered Alpha-Tocopherol by Poly(Lactic-Co-Glycolic) Acid (PLGA) Nanoparticles and Chitosan Covered PLGA Nanoparticles in F344 Rats [0.03%]
聚乳酸-乙醇酸纳米粒和壳聚糖包裹的聚乳酸-乙醇酸纳米粒递送口服α-维生素E在F344大鼠中的生物利用度研究
Lacey C Simon,Rhett W Stout,Cristina Sabliov
Lacey C Simon
It is hypothesized that the bioavailability of αT (alpha-tocopherol), an antioxidant, can be improved when delivered by poly(lactic-co-glycolic) acid (PLGA) nanoparticles (NPs) and chitosan covered PLGA nanoparticles (PLGA-Chi NPs), and th...
Kimberly Harding
Kimberly Harding
Chronic technology and business process disparities between High Income, Low Middle Income and Low Income (HIC, LMIC, LIC) research collaborators directly prevent the growth of sustainable Global Health innovation for infectious and rare di...
Arun Richard Chandrasekaran
Arun Richard Chandrasekaran
DNA has been used as a material for the construction of nanoscale objects. These nanostructures are programmable and allow the conjugation of biomolecular guests to improve their functionality. DNA nanostructures display a wide variety of c...
saltPAD: A New Analytical Tool for Monitoring Salt Iodization in Low Resource Settings [0.03%]
saltPAD：一种新的分析工具用于监测低资源条件下的食盐碘化水平
Nicholas M Myers,Emmerentia Elza Strydom,James Sweet et al.
Nicholas M Myers et al.
We created a paper test card that measures a common iodizing agent, iodate, in salt. To test the analytical metrics, usability, and robustness of the paper test card when it is used in low resource settings, the South African Medical Resear...
Knock-down of ELMO1 in Paediatric Rhabdomyosarcoma Cells by Nanoparticle Mediated siRNA Delivery [0.03%]
纳米颗粒介导的siRNA递送敲低儿童横纹肌肉瘤细胞中ELMO1的表达
Xinyue Huang,Helen Townley
Xinyue Huang
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma that is found in children and has a poor outcome for those with metastatic disease. Two histological groups have been distinguished - embryonal (ERMS) and alveolar (ARMS) forms. ...
Gold Nanoparticles Impinge on Nucleoli and the Stress Response in MCF7 Breast Cancer Cells [0.03%]
金纳米颗粒影响MCF7乳腺癌细胞的核仁和压力反应
Mohamed Kodiha,Hicham Mahboubi,Dusica Maysinger et al.
Mohamed Kodiha et al.
Cancer cells can take up gold nanoparticles of different morphologies. These particles interact with the plasma membrane and often travel to intracellular organelles. Among organelles, the nucleus is especially susceptible to the damage tha...
Formyl-Peptide Receptor Agonists and Amorphous SiO2-NPs Synergistically and Selectively Increase the Inflammatory Responses of Human Monocytes and PMNs [0.03%]
(Form肽受体激动剂和无定形SiO2-纳米颗粒协同并选择性地增强人单核细胞及中性粒白细胞的炎症反应)
Regina Tavano,Daniela Segat,Chiara Fedeli et al.
Regina Tavano et al.
We tested whether amorphous SiO2-NPs and formylpeptide receptor (FPRs) agonists synergistically activate human monocytes and neutrophil polymorphonuclear granulocytes (PMNs). Peptide ligands specifically binding to FPR1 (f-MLP) and to FPR2 ...
Aminosilane Functionalization and Cytotoxicity Effects of Upconversion Nanoparticles Y2O3 and Gd2O3 Co-Doped with Yb3+and Er3 [0.03%]
氨基硅烷功能化及Yb3+和Er3+共掺杂的Y2O3和Gd2O3上转换纳米粒子的细胞毒性效应
Dalia Holanda Chavez,Karla Juarez-Moreno,Gustavo Alonso Hirata
Dalia Holanda Chavez
In this study, luminescent upconversion nanoparticles (UCNPs) Y2O3 and Gd2O3 co-doped with Yb3+ and Er3+ were prepared by the sol-gel method (SG). These NPs are able to absorb near infrared photons and upconvert them into visible radiation ...