Mesoporous silica nano-adjuvant triggers pro-inflammatory responses in Caco-2/peripheral blood mononuclear cell (PBMC) co-cultures [0.03%]
中孔二氧化硅纳米佐剂在Caco-2/外周血单核细胞共培养中的促炎反应触发作用
Maryam Ghasemi,Bita Bakhshi,Reza Khashei et al.
Maryam Ghasemi et al.
The aim of this study was to evaluate the cytotoxicity and immune-stimulatory effect of Mesoporous silica nanoparticle (MSN) Nano-adjuvant on pro-inflammatory cytokines and pattern recognition receptors (PRR) genes expression in Caco-2/PBMC...
Nanotherapeutic modulation of excitotoxicity and oxidative stress in acute brain injury [0.03%]
纳米治疗在急性脑损伤中对兴奋性毒性及氧化应激的调节作用
Rick Liao,Thomas R Wood,Elizabeth Nance
Rick Liao
Excitotoxicity is a primary pathological process that occurs during stroke, traumatic brain injury (TBI), and global brain ischemia such as perinatal asphyxia. Excitotoxicity is triggered by an overabundance of excitatory neurotransmitters ...
Bankuru Navyatha,Seema Nara
Bankuru Navyatha
Cancer nanotheranostics aims at providing alternative approaches to traditional cancer diagnostics and therapies. In this context, plasmonic nanostructures especially gold nanostructures are intensely explored due to their tunable shape, si...
Green synthesis of gold nanoparticles using Acai berry and Elderberry extracts and investigation of their effect on prostate and pancreatic cancer cells [0.03%]
用巴西莓和接骨木提取物绿色合成金纳米颗粒并研究其对前列腺癌和胰腺癌细胞的影响
Nicole Remaliah Samantha Sibuyi,Velaphi Clement Thipe,Kiandokht Panjtan-Amiri et al.
Nicole Remaliah Samantha Sibuyi et al.
Green nanotechnology has drawn major attention because of its ecofriendly and economical biosynthetic protocols. Synthesis of gold nanoparticles (AuNPs) using plant secondary metabolites is considered as a safer and cheaper option. Plants c...
Therapeutic applications of CRISPR/Cas9 in breast cancer and delivery potential of gold nanomaterials [0.03%]
CRISPR/Cas9在乳腺癌治疗中的应用及金纳米材料的递送潜力
Jananee Padayachee,Moganavelli Singh
Jananee Padayachee
Globally, approximately 1 in 4 cancers in women are diagnosed as breast cancer (BC). Despite significant advances in the diagnosis and therapy BCs, many patients develop metastases or relapses. Hence, novel therapeutic strategies are requir...
Effect of intracellular uptake of nanoparticle-encapsulated trehalose on the hemocompatibility of allogeneic valves in the VS83 vitrification protocol [0.03%]
纳米颗粒封装海藻糖的胞内摄取对VS83玻璃化方案同种瓣膜血液相容性的影响
Balamurugan Vasudevan,Qing Chang,Bin Wang et al.
Balamurugan Vasudevan et al.
Trehalose is a disaccharide molecule consisting of two molecules of glucose. Industrially, trehalose is derived from corn starch and utilized as a drug. This study aims to examine whether the integration of nanoparticle-encapsulated trehalo...
Preclinical verification of the efficacy by targeting peptide-linked liposomal nanoparticles for hepatocellular carcinoma therapy [0.03%]
靶向多肽连接脂质纳米颗粒的肝癌治疗效果的临床前验证研究
Cheng-Der Wu,Jen-Chieh Lee,Hang-Chung Wu et al.
Cheng-Der Wu et al.
The purpose of this study was to investigate the efficacy of targeting peptides chemotherapy to overcome adverse event in the conventional chemotherapy for human hepatocellular carcinoma. Previously we reported several cancer-targeting pept...
Halloysite nanotubes as a nature's boon for biomedical applications [0.03%]
halloysite纳米管在生物医学应用中的作用
Swathi Satish,Maithri Tharmavaram,Deepak Rawtani
Swathi Satish
The arena of biomedical science has long been in quest of innovative mediums for diagnostic and therapeutic applications. The latest being the use of nanomaterials for such applications, thereby giving rise to the branch of nanomedicine. Ha...
Anindita De,Nagasamy Venkatesh,M Senthil et al.
Anindita De et al.
Drug delivery to the brain is challenging because of the low permeability of blood-brain barrier, and therefore, optimum concentration of chemotherapeutics in the target area specifically for glioblastoma, an aggressive brain tumor, opens a...
Engineering the hard-soft tissue interface with random-to-aligned nanofiber scaffolds [0.03%]
基于随机和规则排列纳米纤维的软硬组织结合界面的设计与构建
John Nowlin,Mehzubh A Bismi,Baptiste Delpech et al.
John Nowlin et al.
Tendon injuries can be difficult to heal and have high rates of relapse due to stress concentrations caused by scar formation and the sutures used in surgical repair. Regeneration of the tendon/ligament-to-bone interface is critical to prov...