The Role of Isolation Methods on a Nanoscale Surface Structure and its Effect on the Size of Exosomes [0.03%]
分离方法对纳米级表面结构的作用及其对外泌体尺寸的影响
JungReem Woo,Shivani Sharma,James Gimzewski
JungReem Woo
Exosomes are ∼100 nanometre diameter vesicles secreted by mammalian cells. These emerging disease biomarkers carry nucleic acids, proteins and lipids specific to the parental cells that secrete them. Exosomes are typically isolated in bulk...
Detection and Characterization of Circulating Tumour Cells in Multiple Myeloma [0.03%]
多发性骨髓瘤中循环肿瘤细胞的检测与鉴定
Liangxuan Zhang,Sharon Beasley,Natalie L Prigozhina et al.
Liangxuan Zhang et al.
Multiple myeloma (MM) remains an incurable disease despite recent therapeutic improvements. The ability to detect and characterize MM circulating tumour cells (CTCs) in peripheral blood provides an alternative to replace or augment invasive...
Protein Detection Using the Multiplexed Proximity Extension Assay (PEA) from Plasma and Vaginal Fluid Applied to the Indicating FTA Elute Micro Card™ [0.03%]
基于FTA Elute微孔卡的血浆和阴道液样本中蛋白质的多重邻位延伸技术检测方法研究
Malin Berggrund,Daniel Ekman,Inger Gustavsson et al.
Malin Berggrund et al.
The indicating FTA elute micro card™ has been developed to collect and stabilize the nucleic acid in biological samples and is widely used in human and veterinary medicine and other disciplines. This card is not recommended for protein ana...
Elevated Adiponectin Antibody Levels in Sera of Patients with Atherosclerosis-Related Coronary Artery Disease, Cerebral Infarction and Diabetes Mellitus [0.03%]
动脉粥样硬化性冠心病、脑梗死和糖尿病患者血清中抗脂联素抗体水平升高
Takaki Hiwasa,Xiao-Meng Zhang,Risa Kimura et al.
Takaki Hiwasa et al.
Adiponectin secreted from the adipocytes plays pleiotropic, anti-atherosclerotic roles, such as enhancement of insulin secretion and an increase in energy expenditure. The measurement of levels of circulating adiponectin is useful to evalua...
Exosome Secretion - More Than Simple Waste Disposal? Implications for Physiology, Diagnostics and Therapeutics [0.03%]
微囊泡分泌：不仅仅是简单的废物处置？其对生理学、诊断和治疗的意义
Sivappriyan Nagarajah
Sivappriyan Nagarajah
Less than 100 nm in size and spherical in form - exosomes - vesicles expelled and taken up by cells, have ignited a new-found fascination. One which is derived from the sheer variety of exosomal content, ranging from microRNAs to transcript...
Prognostication in Different Heart Failure Phenotypes: The Role of Circulating Biomarkers [0.03%]
不同心力衰竭表型中循环生物标志物的预后价值
Alexander E Berezin
Alexander E Berezin
Heart failure (HF) is multifactorial syndrome with high cardiovascular (CV) morbidity and mortality rates associated with an increasing prevalence worldwide. Measuring plasma levels of circulating biomarkers, i.e., natriuretic peptides, car...
Analyses of 123 Peripheral Human Immune Cell Subsets: Defining Differences with Age and between Healthy Donors and Cancer Patients Not Detected in Analysis of Standard Immune Cell Types [0.03%]
123种外周人类免疫细胞亚群分析：定义与年龄和健康供者及癌症患者之间的差异（这些差异在标准免疫细胞类型的分析中未被检测到）
Lauren M Lepone,Renee N Donahue,Italia Grenga et al.
Lauren M Lepone et al.
Recent advances in human immunology have led to the identification of novel immune cell subsets and the biological function of many of these subsets has now been identified. The recent US Food and Drug Administration approval of several imm...
Protein Complexes in Urine Interfere with Extracellular Vesicle Biomarker Studies [0.03%]
尿液蛋白复合物干扰细胞外囊泡生物标志物研究
Magda Wachalska,Danijela Koppers-Lalic,Monique van Eijndhoven et al.
Magda Wachalska et al.
Urine exosomes (extracellular vesicles; EVs) contain (micro)RNA (miRNA) and protein biomarkers that are useful for the non-invasive diagnosis of various urological diseases. However, the urinary Tamm-Horsfall protein (THP) complex, which fo...
Characterization of a Cell-Culturing System for the Study of Contact-Independent Extracellular Vesicle Communication [0.03%]
一种用于研究接触独立型细胞外囊泡通讯的体外细胞培养系统及其特征分析
Anne Louise Schacht Revenfeld,Evo Kristina Lindersson Søndergaard,Allan Stensballe et al.
Anne Louise Schacht Revenfeld et al.
Appropriate and well-documented in vitro cell-culturing systems are necessary to study the activity and biological function of extracellular vesicles (EVs). The aim of this study was to describe an experimental system, in which dynamic, ves...
Onward to 2016 [0.03%]
迈向2016年
Shidong Jia,Antonio Chiesi,Winston Patrick Kuo
Shidong Jia