The effects of aerobic and anaerobic exercises on circulating soluble-Klotho and IGF-I in young and elderly adults and in CAD patients [0.03%]
有氧和无氧运动对年轻人、老年人以及冠心病患者循环中可溶性Klotho和IGF-I的影响
Moran S Saghiv,D Ben Sira,E Goldhammer et al.
Moran S Saghiv et al.
Different studies support the notion that chronic aerobic exercises training can influence the circulating levels of soluble-Klotho (s-Klotho) and insulin-like growth factor 1 (IGF-I). The effects of s-Klotho include improving the quality o...
Mildly elevated serum total bilirubin is negatively associated with hemoglobin A1c independently of confounding factors among community-dwelling middle-aged and elderly persons [0.03%]
在社区居住的中老年人群中，轻度高胆红素血症与糖化血红蛋白水平独立相关
Ryuichi Kawamoto,Daisuke Ninomiya,Kensuke Senzaki et al.
Ryuichi Kawamoto et al.
Abnormally high glycated hemoglobin (Hb) (HbA1c) is significantly associated with oxidative stress and an increased risk of cardiovascular disease (CVD). Serum total bilirubin (T-B) may have a beneficial role in preventing oxidative changes...
Roles of kallikrein-2 biomarkers (free-hK2 and pro-hK2) for predicting prostate cancer progression-free survival [0.03%]
降钙素基因相关肽在预测前列腺癌进展无病生存期的作用：FREE-HK2和PRO-HK2生物标志物
Anatilde Gonzalez Guerrico,David Hillman,Jeffery Karnes et al.
Anatilde Gonzalez Guerrico et al.
Free human kallikrein 2 (free-hK2) and hK2 pro-form (pro-hK2) have been found to be increased in tumor tissues and serum from patients with prostate cancer. We established semiautomatic assays for free-hK2 and pro-hK2 using a research versi...
A novel method for the isolation of extracellular vesicles and RNA from urine [0.03%]
一种从尿液中分离外泌体和RNA的新方法
Anna Markowska,R Scott Pendergrast,J Stephen Pendergrast et al.
Anna Markowska et al.
The discovery of urinary extracellular biomarkers has been impeded by the lack of efficient methods for the isolation of extracellular vesicles (EVs: exosomes and microvesicles) and extracellular nucleic acid (RNA and DNA) from urine. Ultra...
X-rays and metformin cause increased urinary excretion of cell-free nuclear and mitochondrial DNA in aged rats [0.03%]
x射线和二甲双胍可增加老龄大鼠尿液中细胞核及线粒体dna的排出量
Azhub Gaziev,Serazhutdin Abdullaev,Gulchachak Minkabirova et al.
Azhub Gaziev et al.
Activation of cell death in mammals can be assessed by an increase of an amount of cell-free DNA (cf-DNA) in urine or plasma. We investigated the excretion of cf nuclear DNA (nDNA) and cf mitochondrial DNA (mtDNA) in the urine of rats 3 and...
Circulating cell-free DNA is a predictor of short-term neurological outcome in stroke patients treated with intravenous thrombolysis [0.03%]
循环细胞游离DNA能够预测静脉溶栓治疗的卒中患者的短期神经结果
Alejandro Bustamante,Fernando Mancha,Hada C Macher et al.
Alejandro Bustamante et al.
Circulating cell-free DNA (cfDNA) has been described as a prognostic marker for several diseases. Its prognostic value for short-term outcome in stroke patients treated with intravenous thrombolysis remains unexplored. cfDNA was measured on...
Novel blood test to predict neoplastic activity in healthy patients and metastatic recurrence after primary tumor resection [0.03%]
新型血液检测用于预测健康人的肿瘤活动及主要肿瘤手术后的转移复发
Mohamed Abdouh,Dana Hamam,Vincenzo Arena et al.
Mohamed Abdouh et al.
We reported that single oncosuppressor-mutated (SOM) cells turn malignant when exposed to cancer patients' sera. We tested the possibility to incorporate this discovery into a biological platform able to detect cancer in healthy individuals...
Microvesicles shed from fibroblasts act as metalloproteinase carriers in a 3-D collagen matrix [0.03%]
成纤维细胞释放的微囊作为金属蛋白酶载体在三维胶原基质中的作用
Valentina Laghezza Masci,Anna Rita Taddei,Gabriella Gambellini et al.
Valentina Laghezza Masci et al.
This study shows that fibroblasts migrating into a collagen matrix release numerous microvesicles into the surrounding medium. By spreading in regions of the matrix far distant from cells of origin, microvesicles carry metalloproteinase 9 (...
The signature of circulating microparticles in heart failure patients with metabolic syndrome [0.03%]
代谢综合征心力衰竭患者循环微颗粒的表征研究
Alexander E Berezin,Alexander Kremzer,Tatyana Berezina et al.
Alexander E Berezin et al.
The role of pattern of circulating endothelial cell-derived microparticles, platelet-derived microparticles (PMPs), and monocyte-derived microparticles (MMPs) in metabolic syndrome (MetS) patients with chronic heart failure (CHF) is not sti...
Addition of thrombin reduces the recovery of extracellular vesicles from blood plasma [0.03%]
加入凝血酶减少了从血液等离子体中提取的细胞外囊泡的回收率
Anush Arakelyan,Wendy Fitzgerald,Murad Vagida et al.
Anush Arakelyan et al.
Extracellular vesicles (EVs) are widely studied as a system of intercellular communication, as markers of various diseases, as well as a vehicle for delivery of various bioactive molecules to various cells. Investigation of EVs' structure a...