High-intensity physical exercise increases serum α-klotho levels in healthy volunteers [0.03%]
高强度体育运动可增加健康志愿者血清α-肾上腺素水平
Sven-Jean Tan,Melissa M Chu,Nigel D Toussaint et al.
Sven-Jean Tan et al.
The recently discovered klotho proteins have roles in a diverse range of metabolic processes with the oldest protein, α-klotho, implicated in various cellular pathways in energy, glucose, and phosphate metabolism. Circulating soluble kloth...
A proteomic approach of biomarker candidate discovery for alcoholic liver cirrhosis [0.03%]
酒精性肝硬化生物标志物筛选的蛋白质组学方法研究进展
Krishna Sumanth Nallagangula,V Lakshmaiah,C Muninarayana et al.
Krishna Sumanth Nallagangula et al.
Alcoholic liver disease (ALD) progresses from steatosis to alcoholic hepatitis to fibrosis and cirrhosis. Liver biopsy is considered as the gold standard method for diagnosis of liver cirrhosis and provides useful information about damaging...
Placental protein 13: An important biological protein in preeclampsia [0.03%]
胎盘蛋白13在子痫前期发病机制中的重要作用及临床应用价值
Ranjeeta Gadde,Dayanand Cd,S R Sheela
Ranjeeta Gadde
Placental protein 13 (PP13), a glycan binding protein predominantly expressed in syncytiotrophoblast, dimeric in nature, lacks N-terminal signal peptide, bypasses the endoplasmic reticulum, and secretes into maternal circulation as exosomes...
Improved ovarian cancer EMT-CTC isolation by immunomagnetic targeting of epithelial EpCAM and mesenchymal N-cadherin [0.03%]
改进的卵巢癌上皮间质转化肿瘤细胞免疫磁分离法同时捕获上皮EpCAM和间充质N-钙黏着蛋白细胞
Joseph W Po,Aflah Roohullah,David Lynch et al.
Joseph W Po et al.
Epithelial cell adhesion molecule (EpCAM)-targeted capture remains the most common isolation strategy for circulating tumor cells (CTCs). However, epithelial-to-mesenchymal transition (EMT) leads to decreased epithelial EpCAM expression aff...
Associations between smoking and lipid/lipoprotein concentrations among US adults aged ≥20 years [0.03%]
美国成人中吸烟与脂类/脂蛋白浓度的关系
Ram B Jain,Alan Ducatman
Ram B Jain
Cross-sectional data from National Health and Nutrition Examination Survey for the years 1999-2012 for those aged ≥20 years, fasting for at least 8 h, and classified as smokers and nonsmokers on the basis of observed serum cotinine levels ...
Evolution of proteomic biomarker for chronic liver disease: Promise into reality [0.03%]
慢性肝病蛋白质生物标志物的发展：从前景到现实
Krishna Sumanth Nallagangula,K N Shashidhar,V Lakshmaiah et al.
Krishna Sumanth Nallagangula et al.
Liver is the vital organ for synthesis of proteins whose concentration in blood reflects liver dysfunction. Variations in protein domain can generate clinically significant biomarkers. Biomarker pipeline includes discovery of candidates, qu...
Strategies for enumeration of circulating microvesicles on a conventional flow cytometer: Counting beads and scatter parameters [0.03%]
基于传统流式细胞仪的循环微囊定量策略：计数微球与散射光参数
Mohammad J Alkhatatbeh,Anoop K Enjeti,Sara Baqar et al.
Mohammad J Alkhatatbeh et al.
Enumeration of circulating microvesicles (MVs) by conventional flow cytometry is accomplished by the addition of a known amount of counting beads and calculated from the formula: MV/μl = (MV count/bead count) × final bead concentration. W...
Case report: Whole exome sequencing of circulating cell-free tumor DNA in a follicular thyroid carcinoma patient with lung and bone metastases [0.03%]
病例报告：外周血游离体细胞肿瘤DNA全外显子测序在分化型甲状腺癌肺骨转移患者中的应用
Jianlu Song,Zhili Yang
Jianlu Song
Metastatic follicular thyroid carcinoma (FTC), unresectable or resistance to radioactive iodine, is associated with poor survival. It is believed that this kind of FTC is driven by mutated genes. However, what kind of changes of genome and ...
Correlations of GDF-15 with sST2, MMPs, and worsening functional capacity in idiopathic dilated cardiomyopathy: Can we gain new insights into the pathophysiology? [0.03%]
生长分化因子15与sST2、基质金属蛋白酶和功能恶化能力在特发性扩张型心肌病中的相关性：我们能否获得病理生理的新见解？
Nandini Nair,Enrique Gongora
Nandini Nair
Growth and differentiation factor-15 (GDF-15) has been implicated in fibrosis, inflammation, and ventricular remodeling. The role of GDF-15 in the regulation of cardiac remodeling in idiopathic dilated cardiomyopathy (DCM) remains poorly de...
Journal of Circulating Biomarkers looks forward after being indexed in PubMed Central [0.03%]
《循环生物标志物杂志》被PubMed Central收录后展望未来
Winston Patrick Kuo
Winston Patrick Kuo