Lung ultrasound and biomarkers in primary care: Partners for a better management of patients with heart failure? [0.03%]
基层医疗中的肺部超声和生物标志物：改善心力衰竭患者的管理的合作伙伴？
Mar Domingo,Laura Conangla,Josep Lupón et al.
Mar Domingo et al.
Introduction: The association of pulmonary congestion assessed by lung ultrasound (LUS) and biomarkers-other than N-terminal pro-brain natriuretic peptide (NT-proBNP)-is uncertain. ...
Value of clinical laboratory test for early prediction of mortality in patients with COVID-19: the BGM score [0.03%]
临床实验室检测在COVID-19患者早期死亡预测中的价值：BG M评分的作用
Laura Macias-Muñoz,Robin Wijngaard,Bernardino González-de la Presa et al.
Laura Macias-Muñoz et al.
Background: COVID-19 causes high mortality and long hospitalization periods. The aim of this study was to search for new early prognostic strategies accessible to most health care centers. ...
Exploring adipogenic and myogenic circulatory biomarkers of recurrent pressure injury risk for persons with spinal cord injury [0.03%]
探究脊髓损伤患者压力性损伤复发风险的脂肪生成和肌细胞生成循环生物标志物
Kath M Bogie,Katelyn Schwartz,Youjin Li et al.
Kath M Bogie et al.
Purpose:: To investigate linkages between circulatory adipogenic and myogenic biomarkers, gluteal intramuscular adipose tissue (IMAT), and pressure injury (PrI) history following spinal cord injury (SCI). ...
Analytical validation of the CellMax platform for early detection of cancer by enumeration of rare circulating tumor cells [0.03%]
CellMax平台通过稀有循环肿瘤细胞的计数进行癌症早期检测的分析验证
Pratyush Gupta,Zulfiqar Gulzar,Ben Hsieh et al.
Pratyush Gupta et al.
The CellMax (CMx®) platform was developed to enrich for epithelial circulating tumor cells (CTCs) in the whole blood. This report provides assay performance data, including accuracy, linearity, limit of blank, limit of detection (LOD), spe...
Suming Chen,Amrita Datta-Chaudhuri,Pragney Deme et al.
Suming Chen et al.
There is a wide variety of extracellular vesicles (EVs) that differ in size and cargo composition. EVs isolated from human plasma or serum carry lipid, protein, and RNA cargo that provides insights to the regulation of normal physiological ...
Plasma vitronectin is reduced in patients with myasthenia gravis: Diagnostic and pathophysiological potential [0.03%]
重症肌无力患者血浆结合素减少：诊断和病理生理学潜力
Antonio Junior Lepedda,Giovanni Andrea Deiana,Omar Lobina et al.
Antonio Junior Lepedda et al.
Myasthenia gravis (MG) is an autoimmune disease leading to varying degrees of skeletal muscle weakness. It is caused by specific antibodies directed against definite components in the postsynaptic membrane at the neuromuscular junction (NMJ...
Suppression of cathepsin K biomarker in synovial fluid as a free-drug-driven process [0.03%]
滑液中猫屎蛋白K生物标志物的抑制是一个自由药物驱动的过程
Bennett Ma,Gregg Wesolowski,Bin Luo et al.
Bennett Ma et al.
Cathepsin K (CatK) inhibitors exhibited chondroprotective and pain-reducing effects in animal models, however, improvements were relatively modest at dose levels achieving maximal suppression of CatK biomarkers in urine. In this report, a p...
Adipose mesenchymal stem cells-derived exosomes attenuate retina degeneration of streptozotocin-induced diabetes in rabbits [0.03%]
兔糖尿病视网膜病变模型的脂肪间充质干细胞外泌体治疗作用及机制研究
A Safwat,D Sabry,A Ragiae et al.
A Safwat et al.
This study aimed to evaluate the effect of mesenchymal stem cells (MSCs)-derived exosomes in retina regeneration of experimentally induced diabetes mellitus (DM) in a rabbit model. Exosomes are extracellular vesicles that contain many micro...
Assessment of brain-derived neurotrophic factor and osteopontin in a healthy pediatric population [0.03%]
健康儿科人群脑源性神经营养因子和骨桥蛋白的评估
Joshua D Chew,Larry Markham,Holly M Smith et al.
Joshua D Chew et al.
Biomarkers are routinely used for noninvasive identification or monitoring of disease processes in clinical practice, as well as surrogate end points for drug development. There is a significant lack of data regarding biomarkers in children...
Effect of statins on oxidative DNA damage in diabetic polyneuropathy [0.03%]
他汀类药物对糖尿病多发性神经病患者氧化DNA损伤的影响
Sandra Carrillo-Ibarra,Alejandra Guillermina Miranda-Díaz,Sonia Sifuentes-Franco et al.
Sandra Carrillo-Ibarra et al.
Oxidative stress induces nerve damage in type 2 diabetes mellitus and leads to diabetic polyneuropathy (DPN) and can affect the DNA and antioxidant status. Statins have pleiotropic, protective effects on the peripheral nerves of patients wi...