D-dimer assay interference detected by the discrepancy in D-dimer concentrations at different dilutions: a case report [0.03%]
不同稀释度下D-二聚体浓度差异导致的D-二聚体检测试剂钩状效应病例报告
Marija Milić,Dejana Brkić Barbarić,Iva Lukić et al.
Marija Milić et al.
This case report describes interference from heterophilic antibodies in D-dimer assay. The interference was suspected due to discrepancies between D-dimer concentrations in the original sample and diluted samples, as well as inconsistent cl...
Case Reports
Biochemia medica. 2024 Oct 15;34(3):031001. DOI:10.11613/BM.2024.031001 2024
Molly E Contini,Jeffrey R Spence,David J Stanley
Molly E Contini
Researchers and practitioners are typically familiar with descriptive statistics and statistical inference. However, outside of regression techniques, little attention may be given to questions around prediction. In the current paper, we in...
Slavica Dodig,Ivana Čepelak
Slavica Dodig
Antiphospholipid syndrome (APS) is a rare systemic autoimmune disease characterized by recurrent pregnancy morbidity or thrombosis in combination with the persistent presence of antiphospholipid antibodies (aPLs) in plasma/serum. Antiphosph...
The band count imprecision - a Croatian multicentric pilot study [0.03%]
关于淋巴结计数不准确性的克罗地亚多中心试点工作研究报告
Vanja Radišić Biljak,Višnja Jureša,Valentina Vidranski et al.
Vanja Radišić Biljak et al.
Introduction: Due to high inter-observer variability the 2015 International Council for Standardization in Haematology (ICSH) recommendations state to count band neutrophils as segmented neutrophils in the white blood cel...
Multicenter Study
Biochemia medica. 2024 Jun 15;34(2):020803. DOI:10.11613/BM.2024.020803 2024
Pseudonormokalemia case report - What does it mean to have normal blood potassium? [0.03%]
假正常血钾症病例报告-血钾正常意味着什么？
Tomáš Šálek,David Stejskal
Tomáš Šálek
This case report describes a case of pseudonormokalemia, true hypokalemia. Often, only laboratory values outside the normal range gain attention and false normal results are at risk of not being noticed. However, a disease state may be mask...
Case Reports
Biochemia medica. 2024 Jun 15;34(2):021002. DOI:10.11613/BM.2024.021002 2024
Automated high throughput IgG N-glycosylation sample preparation method development on the Tecan Freedom EVO platform [0.03%]
基于Tecan Freedom Evo平台的自动化高通量IgG型N-聚糖样品前处理方法开发
Borna Rapčan,Maja Hanić,Branimir Plavša et al.
Borna Rapčan et al.
Introduction: Glycomics, focusing on the role of glycans in biological processes, particularly their influence on the folding, stability and receptor interactions of glycoconjugates like antibodies, is vital for our under...
Preanalytical, analytical and postanalytical considerations in circulating microRNAs measurement [0.03%]
循环微小RNA检测的前分析、分析及后分析考量因素
Mustapha Zendjabil
Mustapha Zendjabil
Microribonucleic acids (miRNAs) have emerged as a new category of biomarkers for many human diseases like cancer, cardiovascular and neurodegenerative disorders. MicroRNAs can be detected in various body fluids including blood, urine and ce...
Direct and indirect reference intervals of 25-hydroxyvitamin D: it is not a real vitamin D deficiency pandemic [0.03%]
直接和间接的25-羟基维生素D参考区间：并非真正的维生素D缺乏流行病
Juan José Perales-Afán,Diego Aparicio-Pelaz,Sheila López-Triguero et al.
Juan José Perales-Afán et al.
Introduction: Many studies report vitamin D (25-OH-D) deficiency, although there is no consensus among scientific societies on cut-offs and reference intervals (RI). The aim of this study is to establish and compare RI fo...
Hairy cell leukemia - etiopathogenesis, diagnosis and modern therapeutic approach [0.03%]
毛细胞白血病-病因、诊断和现代治疗方法
Katarzyna Maćkowiak,Magdalena Jankowiak,Karolina Szewczyk-Golec et al.
Katarzyna Maćkowiak et al.
Hairy cell leukemia (HCL) represents 2% of all leukemia cases, with men aged above 55 years being the most affected. The most common symptoms of this type of leukemia include splenomegaly, monocytopenia, and neutropenia. In the basic blood ...
Tamara Janković,Miroslava Janković
Tamara Janković
The investigation of biomarkers is constantly evolving. New molecules and molecular assemblies, such as soluble and particulate complexes, emerged as biomarkers from basic research and investigation of different proteomes, genomes, and glyc...