Proteomics in myelodysplastic syndromes: towards novel prognostic and diagnostic biomarkers [0.03%]
骨髓衰竭性疾病蛋白质组学：新型预后及诊断生物标志物研究
Ruđer Novak,Inga Mandac Smoljanović,Lovorka Grgurević
Ruđer Novak
Myelodysplastic neoplasms (MDS) are clonal hematopoietic disorders defined by ineffective hematopoiesis, cytopenias, and variable risk of progression to acute myeloid leukemia. Although genomic and epigenomic studies have provided insight i...
Cross-interference of hemolysis, icterus and lipemia: A study with real patient samples [0.03%]
溶血、黄疸和脂血之间的相互干扰研究：真实患者样本的研究
Hatice Bozkurt Yavuz,Soycan Tüner
Hatice Bozkurt Yavuz
Introduction: Hemolysis, icterus, and lipemia (HIL) are frequent preanalytical interferences, leading to erroneous results or sample rejection. While individual effects of these indices have been studied, their interferen...
Factors associated with Gla-rich protein serum concentrations in healthy adults [0.03%]
健康成年人GTP水平的影响因素分析
Catarina Marreiros,Carla Viegas,Selene Nunes et al.
Catarina Marreiros et al.
Introduction: Gla-rich protein (GRP) is a vitamin K-dependent protein involved in the regulation of ectopic calcification and inflammatory processes. However, data on circulating GRP concentrations in healthy adults remai...
Observational Study
Biochemia medica. 2026 Jun 15;36(2):020709. DOI:10.11613/BM.2026.020709 2026
Homovanillic acid and vanillylmandelic acid as neuroblastoma biomarkers in children [0.03%]
儿茶酚胺代谢产物高香草酸和香草基扁桃酸作为神经母细胞瘤的生物标志物
Sina Kavalakatt,Josko Ivica
Sina Kavalakatt
Neuroblastoma (NBL) is the most common pediatric tumor with the highest fatality rate. The survival rate is improved when NBL is diagnosed in children under 1 year of age, but the diagnosis is complex due to the heterogeneity of the disease...
Verification of harmonized reference intervals in Croatia: is it time for a change? [0.03%]
克罗地亚和谐参考区间的验证：是否到了改变的时候？
Iva Friščić,Ida Burazer,Andrea Radeljak et al.
Iva Friščić et al.
Introduction: The study of harmonized reference intervals (RIs) in Croatia was published in 2004. Since then, notable methodology and population characteristics changes have occurred in the Croatian population, highlighti...
Optimization of icterus interference thresholds for 45 parameters on the Atellica analyzers CH930 and IM1300 [0.03%]
优化Atellica分析仪CH930和IM1300的45个参数胆红素干扰阈值
Damien Leleu,Damien Denimal,Laurence Duvillard
Damien Leleu
Introduction: The data provided by the manufacturer regarding icterus interference on the various parameters measured on Atellica analyzers are very incomplete, potentially leading to erroneous result interpretation. We a...
Myocardial fibrosis and viability: the role of imaging and biomarkers in patients with chronic total occlusion on coronary angiography [0.03%]
慢性完全闭塞冠状动脉造影患者的影像学和生物标志物在心肌纤维化和心肌存活中的作用
Željka Dragila Tomašić,Lea Maršić,Anamaria Mikolčić et al.
Željka Dragila Tomašić et al.
In patients with chronic total occlusion on coronary angiography, myocardial viability assessment is an essential tool in guiding treatment decisions, especially revascularization. Current non-invasive tests are often limited by the presenc...
A challenging laboratory case due to inappropriate sampling through an antiseptic barrier cap [0.03%]
一种由于使用消毒屏障帽不当采样而导致的具有挑战性的实验室病例
Giovanni Introcaso,Giorgia Piras,Giorgia Mandelli et al.
Giovanni Introcaso et al.
Antiseptic barrier caps are currently used as novel tools in critically ill patients to achieve sterility of the blood sampling site and to prevent central line-associated bloodstream infections in the intensive care unit. A clinical and la...
Case Reports
Biochemia medica. 2026 Jun 15;36(2):021001. DOI:10.11613/BM.2026.021001 2026
Extrapyramidal and anticholinergic reactions in an adolescent patient: a case for pharmacogenetic consideration [0.03%]
青少年患者 extrapyramidal 和抗胆碱能反应的病例：药理基因组学考虑因素的一个例子
Iris Žunić Išasegi,Ivana Stefanović,Marta Okružnik Želalić et al.
Iris Žunić Išasegi et al.
Adolescent patients with borderline personality traits present a significant clinical challenge due to their polymorphic symptomatology occurring together with ongoing psychological and physiological development. While psychotherapy remains...
Case Reports
Biochemia medica. 2026 Jun 15;36(2):020902. DOI:10.11613/BM.2026.020902 2026
Preanalytical study concerning the influence of tube type and centrifugation conditions on the concentration of calprotectin in ascites [0.03%]
关于管类型和离心条件对腹水中Calprotectin浓度影响的前分析研究
Adrijana Dorotić,Marija Siter-Kuprešanin,Helena Čičak et al.
Adrijana Dorotić et al.
Introduction: Concentration of calprotectin in ascitic fluid has been proposed as the possible diagnostic marker for spontaneous bacterial peritonitis. This study aimed to choose the optimal preanalytical conditions for t...