A Seven-Gene Signature for the Diagnosis of Parkinson's Disease and Immune Infiltration Analysis [0.03%]
帕金森病的七基因标记及免疫浸润分析
Chengqun Wei,Rui Xue,Zhan Gao et al.
Chengqun Wei et al.
The objective was to identify the predictive markers and develop a diagnostic model with predictive markers for Parkinson's disease (PD) and investigate the roles of immune cells in the disease pathology. Microarray datasets of PD and contr...
Upholding Protocol - The Logic of Diagnosis - Tribute to E. M. Nicholls (1927-2011) [0.03%]
遵守规范——诊断的逻辑——纪念E. M. Nicholls (1927-2011)
Alan E Stark,Paulo A Otto
Alan E Stark
Max Nicholls had an almost unique experience as a medical practitioner, researcher and teacher of medical genetics. An earlier paper described his contribution to the etiology of neurofibromatosis. This was followed by Nicholls' own experie...
Mutual Tissue Microchimerism of Hepatoblastomas in Monozygotic Twins From a Familial Adenomatous Polyposis Family [0.03%]
同卵双胞胎肝母细胞瘤的相互组织微嵌合现象：来自家族性腺瘤性息肉病家系的一例报告
Atsuhiro Arisue,Kiyoshi Yamaguchi,Kiyoko Takane et al.
Atsuhiro Arisue et al.
Patients with familial adenomatous polyposis (FAP) have increased risk of hepatoblastoma (HB). We report monozygotic twins with HB in a FAP family. To explore genetic alterations in the HBs of the twins, we carried out whole exome sequencin...
Twins and Their Risks of Cancer as Children, Teenagers or Young Adults: Updated Meta-Analysis and Retrospective Swedish Cohort Study [0.03%]
儿童、青少年或年轻成人时期癌症的患病风险与双胞胎关系的meta分析和瑞典队列研究
Michael F G Murphy,Jian-Rong He,Rema Ramakrishnan et al.
Michael F G Murphy et al.
We investigated whether an observed reduction in overall childhood cancer risk (
Vergard F Skirbekk,Bernt Bratsberg,Christian M Page et al.
Vergard F Skirbekk et al.
Childless individuals have historically faced stigma with assumptions that they lack an interest in future generations because they do not directly contribute to genetic lineage. Individuals share approximately half of their genes with sibl...
Bidirectional Mediation of Cognition by DNA Methylation and Lean Body Mass in Chinese Monozygotic Twins [0.03%]
中国 monozygotic 双胞胎中认知的双向介导：DNA 甲基化和瘦体重的影响
Huihui Li,Tong Wang,Xiaocao Tian et al.
Huihui Li et al.
This study explores whether DNA methylation (DNAm) mediates the association between lean body mass (LBM) and cognition, as well as whether LBM mediates the association between DNAm and cognition. Based on the data of 59 monozygotic twin pai...
Twins of Greece: International Symposium on Twins and Twin-Related Events/Twin Research Reviews: Twins' Neonatal Outcomes; Growth Discordance and Growth Restriction; Twins' Romantic Partners and Alcohol Use/Human Interest Stories: The Paget Twins' Extraordinary Lives; Museum Wing Honors the Lost Rockefeller Twin; Remarkable Co [0.03%]
希腊双胞胎：国际双胞胎及与双胞胎有关的事件研讨会/双胞胎研究评论：双胞胎新生儿结局；生长差异和生长受限；双胞胎恋人的饮酒行为/人类兴趣故事：佩吉特双胞胎非凡的生活；博物馆翼纪念失落的洛克菲勒双胞胎；引人注目的同卵双胞胎中的性别偏差
Nancy L Segal
Nancy L Segal
Highlights from the International Symposium on Twins, held at the University of Crete on May 23-24, 2025, are summarized. The symposium, organized by Dr Maria Markodimitraki, Professor in the Department of Preschool Education at the Univers...
Exploring the Relationship between Polygenic Scores, Community-Shared Socioeconomic Indicators and Major Depressive Disorder Outcome [0.03%]
探究多基因评分、社区共享社会经济指标与抑郁症转归之间的关系
Dante T Sepulveda,Jackson G Thorp,Penelope A Lind et al.
Dante T Sepulveda et al.
Depression, a leading cause of global disability, arises from a multifaceted combination of genetic and environmental components. This study explores the relationship between major depressive disorder (MDD) polygenic scores (PGS), character...