Cap Analysis of Gene Expression Clarifies Transcriptomic Divergence Within Monozygotic Twin Pairs [0.03%]
单卵双胞胎配对转录组差异的系谱分析
Hirokazu Katoh,Hiroaki Asai,Keiko Takemoto et al.
Hirokazu Katoh et al.
Phenotypic variation is the result of gene expression based on complex interaction between genetic and environmental factors. It is well known that genetic and environmental factors influence gene expression, but our understanding of their ...
Estimating the Genetic Contribution to Astigmatism and Myopia in the Mexican Population [0.03%]
估计墨西哥人口中散光和近视的遗传贡献
Talía V Román-López,Brisa García-Vilchis,Vanessa Murillo-Lechuga et al.
Talía V Román-López et al.
Astigmatism and myopia are two common ocular refractive errors that can impact daily life, including learning and productivity. Current knowledge suggests that the etiology of these conditions is the result of a complex interplay between ge...
Effects of Genetic Relatedness of Kin Pairs on Univariate ACE Model Performance [0.03%]
基因亲缘关系对单变量ACE模型性能的影响分析
Xuanyu Lyu,S Mason Garrison
Xuanyu Lyu
The current study explored the impact of genetic relatedness differences (ΔH) and sample size on the performance of nonclassical ACE models, with a focus on same-sex and opposite-sex twin groups. The ACE model is a statistical model that p...
Alan E Stark
Alan E Stark
A simple model by which Hardy-Weinberg proportions are attained in a single generation while maintaining gene frequencies is stated and illustrated. The title 'Quasi-random mating' is proposed. Confusion about the Hardy-Weinberg principle c...
A 10-Year Observational Study on Twin Pregnancy: Role of Fetal Sex Pairing on Obstetric Outcome [0.03%]
一项关于双胞胎妊娠的十年观察研究：胎儿性别配对与围生期结局的关系
Silvia Vannuccini,Sara Bolzonella,Chiara Colucci et al.
Silvia Vannuccini et al.
Fetal sex contributes to the determination of obstetric outcome, as pregnancies carrying male babies seem to have an increased risk of maternal-fetal complications. Most studies have been conducted on singleton pregnancies, whereas less evi...
Roberto Matorras,Alberto Vendrell,Marcos Ferrando et al.
Roberto Matorras et al.
Monozygotic twins (MZT) are 2.5 times more frequent in ART than in natural conceptions. A number of ART-related mechanisms have been probably linked with MZT. Studies that retrospectively analyze the time-lapse (TL) records resulting in MZT...
Mitochondrial DNA Copy Number and Heteroplasmy in Monozygotic Twins Discordant for Schizophrenia [0.03%]
单卵双生子离异精神分裂症的线粒体DNA拷贝数和杂合性研究
Phyo W Win,Shiva M Singh,Christina A Castellani
Phyo W Win
Schizophrenia (SZ) is a severe, complex, and common mental disorder with high heritability (80%), an adult age of onset, and high discordance (∼50%) in monozygotic twins (MZ). Extensive studies on familial and non-familial cases have impli...
The Co-Twin Control Design: Implementation and Methodological Considerations [0.03%]
共胞双生设计：实施方案及方法学考虑因素
Bodine M A Gonggrijp,Steve G A van de Weijer,Catrien C J H Bijleveld et al.
Bodine M A Gonggrijp et al.
Establishing causal relationships in observational studies is an important step in research and policy decision making. The association between an exposure and an outcome can be confounded by multiple factors, often making it hard to draw c...
Genetic and Environmental Influences on Blood Pressure and Serum Lipids Across Age-Groups [0.03%]
年龄组间的遗传和环境因素对血压和血脂的影响
Ke Miao,Yutong Wang,Weihua Cao et al.
Ke Miao et al.
Aging plays a crucial role in the mechanisms of the impacts of genetic and environmental factors on blood pressure and serum lipids. However, to our knowledge, how the influence of genetic and environmental factors on the correlation betwee...
Nacheng Lin,Ping Shen,Huilian Hu et al.
Nacheng Lin et al.
The aim of this study was to investigate the prevalence of anemia in twin pregnancies and the influence of anemia on maternal and neonatal outcomes. This retrospective study included twin pregnant women who delivered in a tertiary hospital ...