Vijay K Sandhu,Lihi Eder,Jensen Yeung
Vijay K Sandhu
Psoriatic arthritis (PsA) is a seronegative inflammatory arthritis often observed in patients with skin psoriasis. Treatment of PsA, especially peripheral PsA, has typically relied on disease-modifying anti-rheumatic agents (DMARDs); howeve...
Back to work from the lockdown: recommendations from the Italian Society of Dermatology (SIDeMaST) and the Italian Forensic Dermatologic Society (SIDeLF) [0.03%]
从封锁中复工：意大利皮肤病学会（SIDeMaST）和意大利法医皮肤科学会（SIDeLF）的建议
Giuseppe Monfrecola,Maria L Musumeci,Gabriella Fabbrocini et al.
Giuseppe Monfrecola et al.
5-Aminolaevulinic acid patch photodynamic therapy for the treatment of actinic keratoses: preliminary results from an Italian study in the real-life setting [0.03%]
5-氨基丁酸贴剂光动力疗法治疗日光性角化病的意大利研究实际应用初步结果
Annunziata Dattola,Carlota Gutiérrez Garcìa-Rodrigo,Sara Tambone et al.
Annunziata Dattola et al.
Background: Photodynamic therapy (PDT) is recommended for both lesion and field therapy of actinic keratoses (AKs). The 5-aminolaevulinic acid (5-ALA) patch PDT is indicated for the treatment of isolated mild AKs (≤1.8 c...
Luca Stingeni,Leonardo Bianchi,Marta Tramontana et al.
Luca Stingeni et al.
Adverse drug reactions (ADRs) are common and influence negatively the patient's therapeutic options. They recognize multiple pathogenic mechanisms, some of immunological origin, and the clinical manifestations involve several organs and sys...
Efficacy and safety of a new topical gel formulation containing retinol encapsulated in glycospheres and hydroxypinacolone retinoate, an antimicrobial peptide, salicylic acid, glycolic acid and niacinamide for the treatment of mild acne: preliminary results of a 2-month prospective study [0.03%]
含有包裹在糖微粒中维甲酸、抗微生物肽、水杨酸、甘醇酸和烟酰胺的新外用凝胶制剂治疗轻度痤疮的疗效与安全性：一个为期两个月的前瞻性研究的初步结果
Alessia Villani,Maria C Annunziata,Eleonora Cinelli et al.
Alessia Villani et al.
Background: Acne vulgaris is a common and chronic skin disease that impacts on physical and psychological perceptions. Combination therapy with topical retinoids and antimicrobial agent is considered the preferred approac...
Rare exon 10 deletion in POLH gene in a family with xeroderma pigmentosum variant correlating with protein expression by immunohistochemistry [0.03%]
极罕见的POLH基因第10外显子缺失型着色性干皮病变异型家系及免疫组化分析
Riccardo G Borroni,Marta Diegoli,Maurizia Grasso et al.
Riccardo G Borroni et al.
Xeroderma pigmentosum (XP) is a rare autosomal recessive disease characterized by severe cutaneous and ocular sensitivity to sunlight, leading to skin cancer. Most XP patients belong to the XP complementation groups (XP-A to XP-G), due to m...
Gianfranco Barabino,Arianna F Agnoletti,Aurora Parodi
Gianfranco Barabino
During the Middle Ages, leprosy sufferers could not live in the city and were forced outside the walls. In the centuries, the Genoese area dedicated several hospitals to lepers, such as S. Lazzaro and Pammatone Hospital, a small leprosarium...
Propylene glycol free 5% minoxidil lotion formulation: cosmetic acceptability, local tolerability, clinical efficacy and in-vitro skin absorption evaluations [0.03%]
不含丙二醇的5％米诺地尔搽剂配方：化妆品接受度，局部耐受性和临床疗效及体外透皮吸收评价
Mauro Barbareschi,Veronica Vescovi,Michela Starace et al.
Mauro Barbareschi et al.
Background: A new propylene glycol (PG)-free 5% minoxidil (Mnx) lotion has been recently commercialized. Aim of this study was to evaluate the acceptability/tolerability and clinical efficacy of 3-month application of thi...
Monogenetic causes of chilblains, panniculitis and vasculopathy: the Type I interferonopathies [0.03%]
I型干扰素病所致的一组遗传性肢端血管炎性疾病：冷球冰症、脂膜炎和血管病
Riccardo Papa,Stefano Volpi,Marco Gattorno
Riccardo Papa
Type I interferonopathies are a clinically heterogeneous group of inherited disorders of the innate immune system characterized by constitutive activation of the type I interferon signaling pathway. Cutaneous vasculopathy, lipodystrophy, in...
How to handle the main drugs to treat autoinflammatory disorders and how we treat common autoinflammatory diseases [0.03%]
治疗自身炎症性疾病的常用药物及其在常见自身炎症性疾病中的应用
Isabelle Koné-Paut,Perrine Dusser
Isabelle Koné-Paut
This article provides an overview of the main drugs to treat autoinflammatory disorders focusing on the four emblematic diseases within this group which represent, to date, the vast majority of patients with monogenic SAID; i.e. familial Me...