The use of doxorubicine at low doses for elevation of LAK-activity toward explants and cells of MC-rhabdomyosarcoma and B16 melanoma resistant to doxorubicin [0.03%]
阿霉素低剂量作用于MC横纹肌肉瘤和耐药B16黑色素瘤细胞及瘤段提高LAK活性的作用
N M Berezhnaya,Yu D Vinnichuk,O B Belova
N M Berezhnaya
Aim: To study the influence of doxorubicin at low doses on antitumor action of activated (LAK) and non-activated lymphocytes from lymph nodes toward tumor cells of mice bearing doxorubicin-resistant and doxorubicin-sensit...
Celecoxib inhibits tumor growth and angiogenesis in an orthotopic implantation tumor model of human colon cancer [0.03%]
塞来昔布抑制人结直肠癌原位种植瘤的生长和新生血管形成
L Wang,W Chen,X Xie et al.
L Wang et al.
Aim: To examine the effect of celecoxib on tumor growth and angiogenesis in an orthotopic implantation tumor model of colon cancer. Methods: ...
Effect of anticancer drugs on production of transforming growth factor and expression of p53 AND Bcl-2 proteins by MCF-7 and T47D cell lines of human breast carcinoma [0.03%]
抗癌药物对人类乳腺癌MCF-7和T47D细胞株转化生长因子产生及p53和Bcl-2蛋白表达的影响
R S Stoika,I A Yakymovych,N I Kashchak et al.
R S Stoika et al.
Aim: To compare the capability of methotrexate, cisplatin, doxorubicine and vincristine to induce production of the transforming growth factor beta(1) (TGF-beta(1)) in two cell lines - MCF-7 and T47D - of human breast car...
Comparative Study
Experimental oncology. 2008 Mar;30(1):35-41. DOI: 2008
VEGF-siRNA silencing induces apoptosis, inhibits proliferation and suppresses vasculogenic mimicry in osteosarcoma in vitro [0.03%]
VEGF-siRNA沉默诱导体外骨肉瘤凋亡并抑制增殖和血管生成模仿现象
J Mei,Y Gao,L Zhang et al.
J Mei et al.
Aim: To inhibit the gene expression of vascular endothelial growth factor (VEGF) with the RNA interference (RNAi) technique and explore its influence on the apoptosis, proliferation, vasculogenic mimicry of osteosarcoma i...
Amifostine can differentially modulate DNA double-strand breaks and apoptosis induced by idarubicin in normal and cancer cells [0.03%]
氨磷汀可调节伊达比星诱导的正常及肿瘤细胞DNA双链断裂与凋亡
K Wozniak,E Gloc,Z Morawiec et al.
K Wozniak et al.
We have previously shown that amifostine differentially modulated the DNA-damaging action of idarubicin in normal and cancer cells and that the presence of p53 protein and oncogenic tyrosine kinases might play a role in this diversity. ...
Antineoplastic and apoptotic effects of cannabinoids. N-acylethanolamines: protectors or killers? [0.03%]
抗癌和凋亡作用的大麻素。N-脂肪酸乙醇胺：保护者还是杀手？
V M Pushkarev,O I Kovzun,M D Tronko
V M Pushkarev
The proapoptotic and antineoplastic properties of cannabinoids with emphasis on effects of N-acylethanolamines were analyzed. Cannabinoids enhanced apoptotic and necrotic processes in many types of tumour cells and tissues. Involvement of d...
Review
Experimental oncology. 2008 Mar;30(1):6-21. DOI: 2008
P D Micco
P D Micco
Editorial
Experimental oncology. 2008 Mar;30(1):4-5. DOI: 2008
A possible mechanism of antitumor activity of 5(5',6'benzocoumaroyl-3')-methylaminouracil in vivo [0.03%]
5-(5`,6`-苯并香豆素-3`)-甲基氨基尿嘧啶的抗肿瘤作用的可能机制研究
H P Kopylchuk,I O Shmarakov,M M Marchenko
H P Kopylchuk
Aim: To analyze possible mechanisms of anticancer activity of hydrobromide 5-(5',6'-benzocoumaroyl-3')-methylaminouracil (BCU) in vivo. Methods: ...
Comparative study of anticancer efficacy of aonitine-containing agent BC1 against ascite and solid forms of Ehrlich's carcinoma [0.03%]
含有药用乌头碱抗肿瘤药物BC1对艾氏癌腹水型和实体型疗效的比较研究
O I Dasyukevich,G I Solyanik
O I Dasyukevich
Aim: To study anticancer activity of conitine-containing agent BC1 in vivo. Methods: BC1 water solution was administered per os to mice...
Comparative Study
Experimental oncology. 2007 Dec;29(4):317-9. DOI: 2007
Differential expression of 16 genes coding for cell cycle- and apoptosis-related proteins in vitamin D-induced differentiation of HL-60 cells [0.03%]
维生素D诱导HL-60细胞分化的与细胞周期和凋亡相关基因的表达差异分析
A Kanli,H Savli
A Kanli
Objective: The aim of the study was to analyze expression of several genes related to cell cycle regulation and apoptosis in realization of 1alpha,25-dihydroxyvitamin D3 (1,25(OH)2D3)-induced differentiation of HL-60 cell...