Analysis of covalent ellipticine- and doxorubicin-derived adducts in DNA of neuroblastoma cells by the ³²P-postlabeling technique [0.03%]
神经母细胞瘤细胞中DNA与共价连接的放线菌素和道诺霉素衍生物加合物的分析：用32p后标记技术
Marie Stiborova,Jitka Poljakova,Tomas Eckschlager et al.
Marie Stiborova et al.
Background: Ellipticine and doxorubicin are antineoplastic agents, whose action is based mainly on DNA damage such as intercalation, inhibition of topoisomerase II and formation of covalent DNA adducts. The key target to ...
Epidemiological of and risk factors for Alzheimer's disease: a review [0.03%]
阿尔茨海默病的流行病学和危险因素：综述性文章
Jana Povova,Petr Ambroz,Michal Bar et al.
Jana Povova et al.
Background: Alzheimer's disease (AD) is the most common form of dementia. It is a degenerative, incurable and terminal disease. The increasing prevalence of AD is, among other reasons, due to population aging, which is, t...
Ingrid Mocikova,Jozef Babela,Vladimir Balaz
Ingrid Mocikova
Background: This article reviews the potential of magnetic resonance imaging (MRI) in prostate cancer diagnosis. Methods: Systematic sc...
Klara Pizova,Katerina Tomankova,Adela Daskova et al.
Klara Pizova et al.
Background: Photodynamic therapy (PDT) is a new modality in cancer treatment. It is based on the tumour-selective accumulation of a photosensitizer followed by irradiation with light of a specific wavelength. PDT is becom...
Hepatic arterial infusion in colorectal carcinoma: is anatomical targeting still relevant in an era of molecularly targeted therapy? [0.03%]
肝动脉输注在结直肠癌治疗中的作用：在分子靶向治疗时代解剖定位仍是关键问题吗？
Bohuslav Melichar
Bohuslav Melichar
Background: Historically, metastatic colorectal carcinoma was regarded as a tumor that is relatively resistant to cytotoxic-agents. Due to the limited number of treatment options, methods have been investigated to enhance...
Osteoprotegerin gene polymorphism is not associated with prosthetic joint infection after total joint arthroplasty in the Czech population [0.03%]
骨保护素基因多态性与捷克人群人工关节置换术后的假体关节感染无关
Zdenka Navratilova,Jiri Gallo,Matej Smizansky et al.
Zdenka Navratilova et al.
Background and aims: Osteoprotegerin (OPG; official gene symbol: TNFRSF11B) is considered a negative regulator of bone resorption via inhibition of osteoclast differentiation. Further, OPG expression has been detected in ...
Genetic variation in key molecules of the Th-17 immune response is not associated with risk for prosthetic joint infection in a Czech population [0.03%]
克罗恩病相关关键分子遗传多态性与捷克人群人工关节感染风险无关联
Zdenka Navratilova,Jiri Gallo,Frantisek Mrazek et al.
Zdenka Navratilova et al.
Background and aims: Prosthetic Joint Infection (PJI) is a serious complication of Total Joint Arthroplasty (TJA). The Th-17 immune response characterised by IL (interleukin)-17A, IL-17F, IL-23, chemotactic cytokines and ...
Endoscopic vs open saphenous vein harvest for coronary artery bypass grafting: a leg-related morbidity and histological comparison [0.03%]
内镜与开放股静脉切取术在冠脉旁路移植中的比较研究：并发症及组织学分析
Radim Brat,Jaroslav Horacek,Jiri Sieja
Radim Brat
Aims: The aim of this study was to compare coronary artery bypass grafting (CABG) using either endoscopic (EVH) or open harvest (OVH). Leg-related morbidity and histological comparison of the veins were the outcome measur...
A complex case of fatal calciphylaxis in a female patient with hyperparathyroidism secondary to end stage renal disease of graft and coexistence of haemolytic uremic syndrome [0.03%]
1例终末期肾病患者合并溶血性尿毒症综合征并发继发性甲状旁腺功能亢进的致死性钙化防御复杂病例报告
Attilio Ignazio Lo Monte,Maurizio Bellavia,Giuseppe Damiano et al.
Attilio Ignazio Lo Monte et al.
Background: Calciphylaxis is a potentially fatal complication of persistent secondary hyperparathyroidism; its cause is still not clear. Unfortunately there is no close relation in severity of clinical picture, serologica...
Peripheral tissue oxygenation during standard CPB and miniaturized CPB (direct oxymetric tissue perfusion monitoring study) [0.03%]
标准CPB与微创CPB下的周围组织氧合水平(直接组织灌注监测研究)
Jiri Mandak,Vladimir Brzek,Vladimir Svitek et al.
Jiri Mandak et al.
Aim: The aim of this study was to compare the impact of standard cardiopulmonary bypass (CPB) with mini CPB on peripheral tissue perfusion. Methods: ...