Unveiling the complexity of neurofibromatosis type 1: Innovations in genetic understanding and clinical management. A narrative review [0.03%]
揭开1型神经纤维瘤病的复杂性：遗传理解和临床管理创新的叙述性回顾
Aurora Jurca,Simona Pop,Claudia Maria Jurca et al.
Aurora Jurca et al.
Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder caused by mutations in the NF1 gene. The most important signs are café-au-lait spots, intertriginous freckling, and neurofibromas. The disease has a progressive course, the p...
Mitochondria in focus: From structure and function to their role in human diseases. A review [0.03%]
聚焦线粒体：从结构和功能到在人类疾病中的作用. 评论文章
Daniel Follprecht,Jakub Vavricka,Viktorie Johankova et al.
Daniel Follprecht et al.
Mitochondria, double-membraned organelles within all eukaryotic cells, are essential for the proper functioning of the human organism. The frequently used phrase "powerhouses of the cell" fails to adequately capture their multifaceted roles...
Serum drug levels and medication adherence in heart failure: A comparative cohort analysis [0.03%]
心力衰竭患者的血清药物水平和药物依从性：一项对比队列分析
Libor Jelinek,Martin Modrak,Jan Vaclavik et al.
Libor Jelinek et al.
Objective: To determine changes in medication adherence in two cohorts of heart failure patients differing by year of data collection and using a direct method of adherence detection - serum drug level testing. ...
Development of Vibrio parahaemolyticus sensitive and specific loop-mediated isothermal amplification combined with lateral flow device [0.03%]
副溶血弧菌敏感特异性等温循环扩增结合侧向流动装置的开发
Xiaoheng Liang,Dan Zhan,Xin Huang et al.
Xiaoheng Liang et al.
Background and aim: Vibrio parahaemolyticus a gram-negative, rod-shaped bacterium with salinophilic properties is found mainly in rivers, oceans, and coastal environments. With the expanding scale of aquaculture in coasta...
Nutritional status and muscle mass loss in patients with COPD, association with lung function, symptoms, comorbidities and long-term survival: data from the National Database Study [0.03%]
慢性阻塞性肺疾病患者的营养状况与肌肉质量下降及其与肺功能、症状、合并症和长期生存的关系：来自国家数据库研究的数据
Eva Volakova,Vladimir Koblizek,Michal Svoboda et al.
Eva Volakova et al.
Aim: To assess nutritional status and muscle mass loss in patients with chronic obstructice pulmonary disease (COPD) from the Czech National Database of COPD and to evaluate the association of nutritional parameters with ...
The burden of multimorbidity in patients with systemic lupus erythematosus - single-centre analysis [0.03%]
系统性红斑狼疮患者的多重疾病负担——单一中心分析
Marketa Dudkova,Martina Skacelova,Pavel Horak et al.
Marketa Dudkova et al.
Aims: Multimorbidity is a growing problem in the general population as well as in patients with rheumatic diseases like systemic lupus erythematosus (SLE). However, patients with SLE have twice the risk of developing mult...
Two de novo UBR1 variants in trans as a cause of Johanson-Blizzard syndrome [0.03%]
两个从头UBR1突变造成乔汉森-布里斯德综合症的原因
Lukas Strych,Tomas Zavoral,Pavla Komrskova et al.
Lukas Strych et al.
Aims/background: Johanson-Blizzard syndrome (JBS) is a rare autosomal recessive disease caused by pathogenic variants in the UBR1 gene. JBS is usually suspected based on characteristic anomalies, but only genetic testing ...
Awareness and knowledge of diabetic retinopathy in diabetics and non-diabetics: A descriptive cross-sectional study [0.03%]
糖尿病患者和非糖尿病患者对糖尿病视网膜病变的认知和了解：一项描述性横断面研究
Diala Walid Abu-Hassan,Mona Freihat,Ibraheem Saleh et al.
Diala Walid Abu-Hassan et al.
Background and aims: Early diagnosis and management of the ever-increasing global consequences of diabetes is of concern to all nations. The populations of developing countries in particular, account for about 75% of the ...
Contemporary review of prognostic markers of prostate cancer from a pathologist perspective [0.03%]
从病理学家角度回顾前列腺癌预后标志物的最新研究进展
Martin Elias,Jan Bouchal,Milan Kral et al.
Martin Elias et al.
Prostate cancer is the most frequently diagnosed malignant tumour in men worldwide. To treat this condition, prognostic markers to distinguish indolent from aggressive disease, and biomarkers for metastatic forms are needed. From a patholog...
FOXP3, IL-35, and PD-L1 in intra- and peritumoral lymphocytic infiltrate of cutaneous melanomas as an important part of antitumor immunity [0.03%]
皮肤黑色素瘤中肿瘤内和肿瘤周淋巴细胞浸润中的FOXP3、IL-35和PD-L1是抗肿瘤免疫的重要组成部分
Vladimir Zidlik,Pavel Hurnik,Yvetta Vantuchova et al.
Vladimir Zidlik et al.
Background: The tumor microenvironment is a significant mediator enabling tumor growth and progression. Tumor-infiltrating lymphocytes (TILs) are an important component of this but tumor cells develop mechanisms by which ...