Tailoring postoperative management through sentinel lymph node biopsy in low- and intermediate-risk endometrial cancer - the SENTRY clinical trial [0.03%]
经哨兵淋巴结活检对低危和中危子宫内膜癌术后处理的优化——SENTRY临床试验
P Sorokin,M Novozhilov,D Utkin et al.
P Sorokin et al.
Background: While total hysterectomy and bilateral salpingo-oophorectomy without lymph node staging are standard for low- and intermediate-risk endometrial cancer, certain histopathologic factors revealed after surgery ca...
Factors influencing overall survival and GvHD development after allogeneic hematopoietic stem cell transplantation - single centre experience [0.03%]
影响allo-HSCT后OS和GVHD发生的因素-单中心经验
M Homolová,E Bojtárová,M Kováčová et al.
M Homolová et al.
Backgrounds: Allogeneic hematopoietic stem cell transplantation (alloHSCT) is a substantial therapeutic procedure for the treatment of a wide spectrum of severe diseases. Despite advancements in treatment and supportive c...
Feasibility of implementation of the early tumor shrinkage as a potential predictive marker to daily clinical practice in patients with RAS wild type metastatic colorectal cancer, treated with cetuximab - a non-interventional observational study [0.03%]
早期肿瘤缩小作为潜在预测标记物在西妥昔单抗治疗的RAS野生型转移性结直肠癌患者中日常临床实践中的可行性——一项非介入性观察研究
J Fínek,M Vočka,J Bauer et al.
J Fínek et al.
Background: With the aim to show the feasibility of early tumor shrinkage (ETS) concept implementation into daily clinical practice in the Czech Republic, a non-interventional, multicentric, single arm, prospective study ...
Potential application of body fluids autofluorescence in the non-invasive diagnosis of endometrial cancer [0.03%]
体液自体荧光在子宫内膜癌无创诊断中的潜在应用
M Švecová,K Fiedlerová,M Mareková et al.
M Švecová et al.
Background: Endometrial carcinoma (EC) is the most common cancer of the female reproductive tract in developed countries. The prognosis and 5-year survival rates are closely tied to the stage diagnosis. Current routine di...
Prostate cancer invasion is promoted by the miR-96-5p-induced NDRG1 deficiency through NF-κB regulation [0.03%]
miR-96-5p通过NF-κB诱导NDRG1缺乏从而促进前列腺癌侵袭
A A Soror,R Eshagh,M R Fahim et al.
A A Soror et al.
Background: The N-myc downstream-regulated gene 1 (NDRG1) has been discovered as a significant gene in the progression of cancers. However, the regulatory mechanism of NDRG1 remained obscure in prostate cancer (PCa). ...
Significance of aberrant DNA methylation for cancer diagnostics and therapy [0.03%]
异常DNA甲基化在癌症诊断和治疗中的意义
T Urban,P Pokorná,O Slabý
T Urban
Background: Epigenetics is a scientific field that covers changes in gene expression that are not caused by the alteration of the nucleotide sequence in the DNA strand. Together with sequential changes, epigenetic reprogr...
Therapy of Castleman's disease with siltuximab - case report and review of literature [0.03%]
用西妥昔单抗治疗Castleman病的病例报告及文献回顾
Z Adam,D Zeman,A Chodacki et al.
Z Adam et al.
Background: Idiopathic multicentric Castleman disease (iMCD) is characterized by constitutional symptoms, enlarged lymph nodes and laboratory test abnormalities, which are primarily related to the overproduction of interl...
Ewing's sarcoma of the urinary bladder - the urologic and pathologic differential diagnosis and current therapeutic options [0.03%]
膀胱尤文肉瘤-泌尿科和病理科鉴别诊断及目前的治疗选择
M Král,D Kurfúrstová,I Hartmann et al.
M Král et al.
Background: Bladder cancer is 11th most common cancer worldwide. Histologically, most of the tumors are classified as urothelial carcinomas. Less common variants (squamous cell or adenocarcinomas) usually comprise up to 1...
How patients can help us be even better doctors - educational leaflet "Before I go to the doctor" [0.03%]
如何帮助我们成为更好的医生——教育手册“在看医生之前”
M Světlák,V Šnajdrová,K Fialová
M Světlák
Background: Medical psychology research shows that how a patient communicates appears to be the strongest predictor of physician behavior during a consultation and that patient's activity also influences how much informat...
Enzalutamide and abiraterone in the treatment of patients with metastatic castration-resistant prostate cancer treated previously with chemotherapy [0.03%]
恩杂卢胺和阿比特龙在治疗曾经接受过化疗的转移性去势抵抗性前列腺癌患者中的应用
S Al-Samsam,J Bartoš,V Šámal et al.
S Al-Samsam et al.
Background: The evaluation of treatment outcomes and toxicity in patients with metastatic castration-resistant prostate cancer (mCRPC) treated by enzalutamide or abiraterone after previous docetaxel. ...