Immunohistochemical analysis of CD9, CD29 and epithelial to mesenchymal transition in triple-negative breast cancer [0.03%]
三阴性乳腺癌CD9、CD29的免疫组化分析及上皮间质转化研究
R- Ondruššek,S Brychtová,M Bezděková et al.
R- Ondruššek et al.
Background: Triple-negative breast carcinomas (TNBC) are a heterogeneous group of tumors with mostly aggressive behaviour and poor prognosis. In association with their aggressive behavior and chemoresistance to treatment,...
Analysis of the effect of baseline detection and early clearance of ct-DNA, on survival outcomes among patients with advanced EGFR-mutant non-small cell lung cancer [0.03%]
基线ctDNA检测和早期转阴对EGFR突变晚期非小细胞肺癌患者生存获益的影响分析
A Joel,R Abarna,R T Chacko et al.
A Joel et al.
Background: To determine if circulating tumor DNA (ct-DNA) dynamics of epidermal growth factor receptor (EGFR) mutation in plasma can identify a subset of patients with EGFR-mutant (EGFR- m) non-small cell lung cancer (NS...
Evaluation pattern within tumor microenvironment and consequent gene expression in oral cancer [0.03%]
肿瘤微环境内的评估模式及其对口腔癌基因表达的影响
A Vasheghani Farahani,M Kavousi,F Jamshidian
A Vasheghani Farahani
Background: Oral squamous cell carcinoma (OSCC) is one of the most common cancers in the head and neck squamous cell cancer group. The increasing frequency of oral carcinomas and their late-stage appearance is a major wor...
D Nižňanská,M Vlachová,J Gregorová et al.
D Nižňanská et al.
Background: Multiple myeloma (MM) is a heterogeneous hematological malignancy characterized by clonal expansion of malignant plasma cells in the bone marrow. The disease is accompanied by various clinical manifestations, ...
M Eid,Arnošt Martínek,Jiří Dolina et al.
M Eid et al.
Background: The incidence of pancreatic cancer (pancreatic ductal adenocarcinoma - PDAC) is increasing, especially in developed countries. In 2021, 496,000 new PDAC cases were dia-gnosed worldwide. In the Czech Republic, ...
M Domanský,J Kubeš
M Domanský
Background: Cardiovascular diseases represent the most common non-oncologic cause of death in patients following radiotherapy (RT) in the thoracic region. Radiation-induced heart disease (RIHD) can manifest as various het...
The guidelines for clinical practice for carriers of germline mutations in hereditary breast, ovarian, prostate, and pancreatic cancer predisposition genes BRCA1, BRCA2, PALB2, ATM, and CHEK2 (4.2024) [0.03%]
遗传性乳腺癌、卵巢癌、前列腺癌和胰腺癌易感基因BRCA1、BRCA2、PALB2、ATM和CHEK2携带者的临床实践指南（2024版）
P Kleiblová,J Novotný,D Cibula et al.
P Kleiblová et al.
The Guidelines for Clinical Practice for carriers of pathogenic variants in clinically relevant cancer predisposition genes define the steps of primary and secondary prevention that should be provided to these individuals at high risk of de...
Advanced gastric cancer with peritoneal oligometastases treated with adaptive radiotherapy and concurrent chemotherapy [0.03%]
适应性放疗联合同步化疗治疗腹膜寡转移的晚期胃癌患者
Y Hama,E Tate
Y Hama
Background: There are no reports of concurrent chemoradiotherapy for gastric cancer with peritoneal oligometastases. Case description: ...
Copy number variation and clinical response to chemotherapy and bevacizumab in the Czech metastatic colorectal cancer patients [0.03%]
捷克转移性结直肠癌患者化疗和贝伐单抗的临床反应中的拷贝数变异分析
J Stránská,K Bartáková,Z Rožánková et al.
J Stránská et al.
Background: Despite bevacizumab being the first biological agent approved for the treatment of metastatic colorectal cancer (mCRC), there is not any established DNA biomarker to improve its efficacy and personalize the tr...
Pancreatic cancer - epidemiology, risk factors, nutritional and infl ammatory prognostic and predictive factors [0.03%]
胰腺癌的流行病学、危险因素及营养和炎症预后及预测因素
J Homolová,D Ondruš,M Ondrušová et al.
J Homolová et al.
Background: Pancreatic cancer remains one of the most challenging malignancies to treat, with consistently low survival rates despite advances in medical research. The identification and validation of effective prognostic...