Hepatic Injury Induced by a Single Dose of Nivolumab - a Case Report and Literature Review [0.03%]
纳武单抗(Nivolumab)致肝损伤1例及文献复习
J Kopecký,O Kubecek,T Geryk et al.
J Kopecký et al.
Background: The use of nivolumab in the treatment of metastatic melanoma has become well established during past years. Despite its undeniable efficacy, immune-related side effects may occur, including acute liver injury....
Clinical Management and Outcome in Extreme Retroperitoneal Growing Teratoma Syndrome of Testicular Origin - Clinical Management and Effect of the Treatment [0.03%]
极端盆腔生长型畸胎瘤综合征的临床处理及治疗效果及相关因素分析
S Huľová,R Aziri,M Chovanec et al.
S Huľová et al.
Background: Growing teratoma syndrome (GTS) is an uncommon clinical finding in patients treated for testicular cancer. It is diagnosed during or after chemotherapy as an expanding tumour mass not responding to the treatme...
Gorlin-Goltz syndrome [0.03%]
戈林-高兹综合征
V Bartoš,M Kullová,K Adamicová et al.
V Bartoš et al.
Background: Gorlin-Goltz syndrome is an autosomal dominant inherited disorder characterized by a predisposition to various cancers. Clinicopathological findings of syndrome are very diverse and many symptoms begin to mani...
Gastrointestinal Stromal Tumours of the Rectum - Evaluating the National Registry Data with Respect to its Use in Clinical Practice [0.03%]
胃肠道间质瘤的直肠肿瘤-评估国家登记数据及其在临床实践中的应用
R Svatoň,Z Kala,P Kysela et al.
R Svatoň et al.
Background: Gastrointestinal stromal tumours (GIST) are rare malignant mesenchymal tumours with an incidence of 1 in 100,000. They represent only 5% of gastrointestinal tumours. The GISTs are mainly located in the stomach...
High Level of Circulating Microparticles in Patients with BCR/ABL Negative Myeloproliferative Neoplasm - a Pilot Study [0.03%]
BCR-ABL阴性骨髓增生性肿瘤患者循环微颗粒水平的一项初步研究
M H Aswad,J Kissová,L Rihova et al.
M H Aswad et al.
Background: Microparticles (MPs) are small (0.1-1 μm) cell-derived vesicles released during activation or apoptosis, with a surface-exposed phosphatidylserine along with antigens indicating the cellular origin. The l...
Chromothripsis - Extensive Chromosomal Rearrangements and Their Significance in Cancer [0.03%]
染色体断裂基因重组在癌症中的意义
K Závacká,K Plevová,M Jarošová et al.
K Závacká et al.
Background: Chromosome rearrangements play an important role in cancer pathophysiology. Recently, chromothripsis has been proposed among the mechanisms leading to their formation. Chromothripsis leads to fragmentation of ...
J Navrátil,A Poprach,R Lakomý et al.
J Navrátil et al.
Background: With advancements in diagnostic techniques, oligometastatic prostate cancer is diagnosed in patients who were, in the past, considered to have localized disease. Moreover, evidence of the effectiveness of trea...
Therapy of Relapsed/Refractory Acute Lymphoblastic Leukemia Today and Tomorrow [0.03%]
复发/难治急性淋巴细胞白血病的治疗：现状和未来展望
Š Hrabovský,F Folber,M Doubek
Š Hrabovský
Background: New diagnostics and treatments, including the use of new drugs, have advanced considerably the treatment of acute lymphoplastic leukemia (ALL) in the past few years. Monoclonal antibodies and immunoconjugates ...
P Burkoň,M Slavik,T Kazda et al.
P Burkoň et al.
Background: Stereotactic body radiotherapy (SBRT) is used to treat localized tumor lesions and consists of applying high doses of radiation to a small number of fractions using specially equipped linear accelerators, mode...