Real-world PD-L1 testing, fi rst-line therapy for advanced NSCLC, and fi rst-line pembrolizumab monotherapy utilization and outcomes for metastatic NSCLC in the Czech Republic [0.03%]
程序性死亡配体1(real-world)检测和晚期非小细胞肺癌(NSCLC)一线治疗以及帕博利珠单抗在转移性NSCLC一线单药使用和结果在捷克共和国
M L Santorelli,M Chrápavá,K Hrabcová et al.
M L Santorelli et al.
Background: This study aimed to describe real-world PD-L1 testing and first-line (1L) treatment patterns for advanced non-small cell lung cancer (NSCLC), and clinical outcomes for metastatic NSCLC after 1L pembrolizumab m...
R Soumarová,J Havlík
R Soumarová
Background: Cervical cancer has shown declining incidence and mortality in recent years, yet it remains a serious societal problem. This is mainly due to its prevalence in younger age groups and the relatively difficult t...
M Ondrušová,S Vándor Svidová,A Blažová et al.
M Ondrušová et al.
Objective: The present publication focuses on the analysis of the development of basic epidemiological indicators of the most frequently occurring cancers in elderly population in Slovakia. ...
S Batko
S Batko
Background: Gastrointestinal stromal tumors (GISTs) are rare tumors of the digestive tract that have seen significant advances in diagnosis and treatment in recent years. A key breakthrough was the identification of c-KIT...
Trends of the use of pegylated granulopoiesis growth factors in clinical practice - single oncology centre experience since 2005 [0.03%]
本中心2005年以来促粒细胞生长因子临床使用趋势分析
S Vokurka,V Kliment,J Kulhánková et al.
S Vokurka et al.
Background: Pegylated granulopoesis growth factors (pegylated granulocyte colony-stimulating factors - PGCSF), pegfilgrastim and lipegfilgrastim, have established indications in the prophylaxis of febrile neutropenia (FN)...
Predictors of maintaining motivation to exercise in women with breast cancer - preliminary results of a qualitative study [0.03%]
维持乳腺癌女性运动动机的预测因子-定性研究的初步结果
I Burešová,J Halámková,I Kiss et al.
I Burešová et al.
Background: Given the importance of physical activity (PA) for treatment success, survival and quality of life in cancer patients, this study aimed to identify predictors that influence patients' ability to maintain PA du...
New treatment options for generalized HER2-positive breast cancer in higher-line systemic palliative therapy [0.03%]
赫赛特定阳性广泛转移乳腺癌的后线系统姑息治疗的新治疗选择
J Špaček
J Špaček
Background: HER2-positive breast cancer occurs in about 15-20 % of all breast cancers. It is both a prognostic and predictive biomarker and the introduction of anti-HER2 therapy over the last 20 years has significantly im...
Percutaneous thermal segmentectomy using balloon-occluded microwave ablation fol lowed by balloon-occluded transarterial chemoembolization [0.03%]
经皮热段切除使用球囊闭塞微波消融紧接着球囊闭塞经动脉化疗栓塞
D-D Chlorogiannis,S Spiliopoulos,S Grigoriadis et al.
D-D Chlorogiannis et al.
Background: Solitary hepatocellular carcinoma (HCC) with a diameter of 3-5 cm represents a challenging clinical entity, especially for non-surgical candidates due to comorbidities. ...
Real-time MRI-guided radiation therapy for choroidal metastases after hippocampal avoiding whole brain radiotherapy [0.03%]
海马保护性全脑放疗后实时MRI引导放射治疗脉络膜转移瘤
Y Hama,E Tate
Y Hama
Background: Eye tumors are moving targets, but there have been no reports of radiation therapy with real-time monitoring. Case: A 54-ye...
Diff erent expression of genes involved in unfolded protein response in multiple myeloma and extramedullary dis ease patients [0.03%]
多发性骨髓瘤和髓外病变患者未折叠蛋白反应相关基因的不同表达
A Dostálová,M Vlachová,T Růžičková et al.
A Dostálová et al.
Background: The unfolded protein response (UPR) enables myeloma cells to overcome the stress conditions arising from excessive proteosynthesis and thus provides a survival advantage for myeloma cells. Extramedullary disea...