From traditional Chinese medicine to molecular oncology - pleiotropic effects of tauroursodeoxycholic acid [0.03%]
从传统中药到分子肿瘤学-denpsorehchaxian的多效性作用研究进展
B Vavrušáková,R Bartošová,M Svoboda et al.
B Vavrušáková et al.
Background: Tauroursodeoxycholic acid (TUDCA) is a naturally occurring hydrophilic bile acid in the human body. Its therapeutic effects have been recognized in traditional Chinese medicine since ancient times and continue...
Integrative medicine in oncology - between science, ideology, and pragmatism [0.03%]
肿瘤学中的整合医学--科学、意识形态与实用主义之间的平衡
M Světlák
M Světlák
Background: Integrative medicine, which combines evidence-based conventional and complementary approaches, can significantly contribute to symptom management, improvement of quality of life, and empowerment of cancer pati...
A Fried,J Strmisková,K Magerová et al.
A Fried et al.
Background: Human cytomegalovirus (hCMV) is a widely prevalent herpesvirus that typically remains asymptomatic in immunocompetent individuals. However, in immunocompromised patients, it can cause severe clinical complicat...
Extravasation (paravasation) of anticancer drugs - updated recommendations (2025) for standard care in the Czech Republic based on multidisciplinary cooperation [0.03%]
抗肿瘤药物外渗(旁路渗出)- 基于多学科合作的捷克共和国标准护理更新建议(2025年)
S Vokurka,V Maňásek,D Navrátilová Hrabánková et al.
S Vokurka et al.
Background: Extravasation (paravasation) of chemotherapy and other anticancer drugs represents a significant complication in the patient care. Preventive and therapeutic measures effectively reduce the incidence, severity...
Practical recommendations for the use of PARP inhibitors in the treatment of ovarian cancer [0.03%]
卵巢癌治疗中实用的PARP抑制剂使用建议
D Cibula,R Kocián
D Cibula
Background: There is no doubt that PARP inhibitors (PARPi) have significantly improved the prognosis of patients with advanced-stage ovarian cancer. In the history of treatment for this disease, their impact is second onl...
Long-term treatment effi cacy in a rapid growth malignant undiff erentiated lung tumor [0.03%]
恶性快速增长的未分化型肺癌的长期治疗效果
Y Maezawa,Y Sasatani,G Ohara et al.
Y Maezawa et al.
Background: Treatment of patients with malignant undifferentiated lung tumors who also have diffuse lung disease is difficult, especially when the tumor grows rapidly. Herein we present a malignant undifferentiated tumor ...
Successful treatment of sepsis caused by multidrug-resistant Pseudomonas aeruginosa using cefi derocol in an immunocompromised hematological cancer patient fol lowing allogeneic hematopoietic stem cell transplantation [0.03%]
异基因造血干细胞移植后成功使用西夫他宁治疗免疫功能低下血液肿瘤患者多药耐药绿脓杆菌感染所致脓毒症
M Navrátil
M Navrátil
Background: In present days we have the possibility to use new antibiotic drug cefiderocol for the treatment of multiple drug resistant bacterial infections. This infections are the result of preceding and repeating antib...
Total mesometrial resection for the treatment of cervical cancer - an exploratory study of feasibility, safety and oncological outcomes in developing countries [0.03%]
宫颈癌的总宫体切除术治疗 IIIA2 期宫颈癌:在发展中国家可行性和安全性的探索性研究及肿瘤结局报告
P Sorokin,S Kulikova,A Stepanyan et al.
P Sorokin et al.
Background: Total mesometrial resection (TMMR) has shown excellent locoregional control for treatment of cervical cancer without adjuvant radiation therapy in highly selected centers. However, this procedure was never eva...
Real-world PD-L1 testing, fi rst-line therapy for advanced NSCLC, and fi rst-line pembrolizumab monotherapy utilization and outcomes for metastatic NSCLC in the Czech Republic [0.03%]
程序性死亡配体1(real-world)检测和晚期非小细胞肺癌(NSCLC)一线治疗以及帕博利珠单抗在转移性NSCLC一线单药使用和结果在捷克共和国
M L Santorelli,M Chrápavá,K Hrabcová et al.
M L Santorelli et al.
Background: This study aimed to describe real-world PD-L1 testing and first-line (1L) treatment patterns for advanced non-small cell lung cancer (NSCLC), and clinical outcomes for metastatic NSCLC after 1L pembrolizumab m...
R Soumarová,J Havlík
R Soumarová
Background: Cervical cancer has shown declining incidence and mortality in recent years, yet it remains a serious societal problem. This is mainly due to its prevalence in younger age groups and the relatively difficult t...