MET exon 14 skipping gene-positive lung adenocarcinoma associated with atypical adenomatous hyperplasia in lungs and metachronous lung adenocarcinoma [0.03%]
肺腺癌合并肺不典型腺瘤样增生和异时性肺腺癌一例及其基因突变分析
H Sunabe,Y Maezawa,T Shiozawa et al.
H Sunabe et al.
Background: Recently, there has been interest in the CT imaging characteristics of lung cancer positive for mesenchymal-epithelial transition (MET) exon14 skipping mutation. Herein, we present a patient with MET exon 14 s...
Cardiac metastasis of urothelial carcinoma mimicking ST-elevation myocardial infarction [0.03%]
类似急性心肌梗死的尿路上皮癌心脏转移灶病例报告
L Chaloupková,V Suchánek,T Büchler
L Chaloupková
Background: Urothelial carcinoma (UC) is the second most common malignancy of the urinary tract. While distant metastases are relatively frequent in advanced UC, cardiac involvement is exceedingly rare and typically asymp...
Histopathological predictive factors of sentinel node positivity in melanoma in the Blumenau-SC Brazilian region [0.03%]
巴西南大河州布卢梅瑙地区黑色素瘤哨点淋巴结阳性的组织病理学预测因素
R Kraft Rovere,V D de Almeida,C H de Freitas et al.
R Kraft Rovere et al.
Background: This study aims to evaluate the relationship between sentinel lymph node positivity and risk factors associated with cutaneous melanoma, as well as the epidemiological data of patients diagnosed with this cond...
Integrated clinical-bio logical infrastructure for precision oncology in pancreatic adenocarcinoma - experience with REDCap implementation in an academic setting [0.03%]
基于REDcap实施的精准肿瘤学胰腺癌临床生物学基础设施建设经验
P Moravčík,P Weselá,V Kocandová et al.
P Moravčík et al.
Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive solid malignancies, characterized by poor five-year survival and limited options for early detection. The development of precision oncology...
Polyclonal hypergammaglobulinemia, infiltration of the salivary glands, lymphadenopathy, and kidney damage - Mikulicz's disease, Sjögren's syndrome, or Castleman's disease? Case report and overview of differential diagnosis and treatment [0.03%]
多克隆高丙种球蛋白血症、唾液腺浸润、淋巴结病和肾损伤：Mikulicz病、干燥综合征还是卡斯尔曼病？病例报告及鉴别诊断与治疗概述
Z Adam,Z Fojtík,Z Řehák et al.
Z Adam et al.
Background: Polyclonal hypergammaglobulinemia has a variety of causes, which we outline in the text. Regularly, very high concentrations of polyclonal immunoglobulins are observed in IgG4-related disease, Sjögren's syndr...
J Staňková,M Hajdúch
J Staňková
Background: Biological sex and gender significantly influence cancer incidence, biology, disease progression, treatment response, and long-term survival. These differences arise from a complex interplay of hormonal, genet...
M Makohusová,E Kaiserová,A Kolenova et al.
M Makohusová et al.
Background: Childhood cancer is a serious health issue that still does not receive sufficient attention on a global scale compared to cancer in adults. Specialized pediatric cancer registries play a crucial role in collec...
Circulating tumor DNA in HPV-associated head and neck cancers - a novel clinical tool in the era of precision oncology [0.03%]
人乳头瘤病毒相关头颈癌的循环肿瘤DNA——精准肿瘤学时代的新型临床工具
M Lacek,R Lohynská
M Lacek
Background: Head and neck squamous cell carcinoma (HNSCC) represents a significant global oncological challenge with a rising incidence, particularly due to HPV-associated oropharyngeal squamous cell carcinomas (OPSCC). T...
Stereotactic radiotherapy (SIMT FSRT) of brain metastases in a patient with ALK-positive lung adenocarcinoma [0.03%]
ALK阳性的肺腺癌脑转移患者的立体定向放射治疗（分次立体定向放射治疗）
L Hnidáková,P Pospíšil,J Garčic et al.
L Hnidáková et al.
Precision medicine in hemato-oncology - treatment of refractory multiple myeloma with massive extramedullary involvement using BRAF/ MEK inhibitors [0.03%]
血液肿瘤精准医学--采用BRAF/MEK抑制剂治疗难治且瘤负荷极高的浆细胞瘤患者
M Štork,J Kotašková,E Ondroušková et al.
M Štork et al.
Background: Multiple myeloma (MM) with extramedullary disease (EMD) represents a subgroup with particularly poor prognosis. The application of precision medicine principles, especially targeted therapy based on the tumor'...