Survival Outcomes in Patients With Locally Advanced NSCLC Converted to Resectable Disease by Neoadjuvant Therapy [0.03%]
新辅助治疗后转化为可手术切除的局部晚期非小细胞肺癌患者的生存情况
Ece Duygu Gulsen,Rashad Ismayilov,Aydan Farzaliyeva et al.
Ece Duygu Gulsen et al.
Background/aim: Neoadjuvant therapy enables disease conversion to resectability in selected patients with locally advanced non-small-cell lung cancer (NSCLC) but real-world survival outcomes in this setting are not well d...
Development of a Universal Electric Medical Clamp for Rotational Intraperitoneal Aerosol Chemotherapy [0.03%]
一种用于旋转腹腔内超声雾化化疗的通用型电动医用夹的研发
Kyung Hee Han,Seungmee Lee,Hee Seung Kim
Kyung Hee Han
Background/aim: Peritoneal metastasis is associated with poor prognosis and low response rates to systemic chemotherapy due to multidrug resistance. Pressurized intraperitoneal aerosol chemotherapy (PIPAC) has improved lo...
Cannabidiol Enhances SIRT1 and Autophagy for the Maintenance of Human Mesenchymal Stem Cells [0.03%]
大麻二酚通过增强SIRT1和自噬作用来维持人間間質干细胞
Phongsakorn Chueaphromsri,Phongsakorn Kunhorm,Areechun Sotthibundhu et al.
Phongsakorn Chueaphromsri et al.
Background/aim: Mesenchymal stem cells (MSCs) are used to treat various degenerative diseases. However, their therapeutic potential is limited by cellular aging during in vitro cultivation. This study aimed to explore whe...
Association Between PD-L1 Expression and Interstitial Lung Disease Risk in EGFR-mutant NSCLC Treated With EGFR-TKIs [0.03%]
EGFR突变型NSCLC患者接受EGFR-TKI治疗时PD-L1表达与间质性肺疾病风险之间的关系
Yutaka Takahara,Ryudai Abe,Sumito Nagae et al.
Yutaka Takahara et al.
Background/aim: Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are the standard treatment therapy for non-small cell lung cancer (NSCLC) with EGFR mutations. However, patients harboring the exon 2...
Adjuvant Molecular Hydrogen Therapy in SLE-associated Pulmonary Arterial Hypertension: A Case Report on Immunomodulatory Effects on Regulatory and Effector Lymphocytes [0.03%]
分子氢辅助治疗系统性红斑狼疮相关肺动脉高压的免疫调节效应：关于调节性和效应淋巴细胞的病例报告
Chin Liu,Jeng-Wei Lu,Chun-Hsien Wu et al.
Chin Liu et al.
Background/aim: Pulmonary arterial hypertension (PAH) is a significant and challenging complication for patients with systemic lupus erythematosus (SLE). It is thought to arise from immune dysregulation and vascular remod...
Evaluating the Reproductive Impact of Pembrolizumab in Mice: Ovarian Function and Hormonal Changes [0.03%]
帕博利珠单抗对小鼠生殖影响的评估：卵巢功能和激素变化
Bengü Mutlu Sütcüoğlu,Osman Sütcüoğlu,Betül Öğüt et al.
Bengü Mutlu Sütcüoğlu et al.
Background/aim: Pembrolizumab, an immune checkpoint inhibitor used in cancer therapy, is associated with immune-related adverse effects, yet its impact on female reproductive health remains unclear. This study aimed to ev...
Analysis of Onset Timing and Risk Factors for Mesalazine-related Adverse Events Using the JADER Database [0.03%]
利用日本上市后药物警戒数据库JADER分析美沙拉嗪相关不良反应的诱发时间及危险因素分析
Kuninori Iwayama,Takayuki Manabe,Yuya Arai et al.
Kuninori Iwayama et al.
Background/aim: Mesalazine is a cornerstone therapy in the treatment of inflammatory bowel disease (IBD). Although formulated for local action, it can cause serious adverse events (AEs), such as interstitial lung disease ...
N-myristoyltransferase 1-mediated Src Myristoylation Promotes Non-receptor Tyrosine Kinase Pathways in Oral Squamous Cell Carcinoma [0.03%]
N-我的ristoyl转移酶1介导的Src肌醇化促进口腔鳞状细胞癌中的非受体酪氨酸激酶途径
Takuma Komiyama,Goro Sugiyama,Hanae Kamohara et al.
Takuma Komiyama et al.
Background aim: N-myristoyltransferase 1 (NMT1), which myristoylates Src, is highly expressed in oral squamous cell carcinoma (OSCC). Although targeted therapies against epidermal growth factor receptor exist, their use i...
Use of Fluorescent Catheters to Prevent Urological Organ Injury in Minimally Invasive Colorectal Surgery: A Retrospective Study [0.03%]
荧光导管在微创结直肠手术中预防泌尿系损伤的使用：一项回顾性研究
Ken Imaizumi,Nobuki Ichikawa,Yudai Yagihashi et al.
Ken Imaizumi et al.
Background/aim: In minimally invasive colorectal surgery, ureteral and urethral injuries are uncommon, but they can have serious complications leading to significant postoperative morbidity. Fluorescent catheters have rec...
Observational Study
In vivo (Athens, Greece). 2026 Jan-Feb;40(1):486-494. DOI:10.21873/invivo.14212 2026
Prurigo Nodularis Increases Risk of Non-alcoholic Fatty Liver Disease and Liver Cirrhosis: A Global-federated Retrospective Cohort Study [0.03%]
结节性痒疹增加非酒精性脂肪肝和肝硬化风险：一项全球分布式病例回顾队列研究
Hui-Chin Chang,Chen-Yu Lin,Hsin-Yo Lu et al.
Hui-Chin Chang et al.
Background/aim: Prurigo nodularis (PN) is a chronic inflammatory skin disorder characterized by intense pruritus and nodular lesions. Emerging evidence suggests PN may be associated with systemic conditions, including liv...