Patient-derived Organoid Model for Predicting the Chemoresponse in Patients With Colorectal Cancer [0.03%]
基于患者的类器官模型预测结直肠癌患者化疗反应
Kiyoun Yi,Sung Hee Park,Dong Uk Kim et al.
Kiyoun Yi et al.
Background/aim: Cancer mortality has decreased due to the contribution of extensive research on cancer treatment, including chemotherapy, radiation, and immunotherapy. However, histopathologically similar tumors originati...
Postoperative Surgical Site Infections in Spine Surgery: Can the Duration of Surgery Predict the Pathogen Spectrum? [0.03%]
术后脊柱手术切口感染：手术时间能够预测病原体吗？
Saeed Algarny,Akanksha Perera,Philipp Egenolf et al.
Saeed Algarny et al.
Background/aim: Surgical site infection (SSI) is a severe complication of spinal surgery, which typically results in prolonged length of hospital stay, an increased number of revision surgeries, re-hospitalizations, worse...
Targeting Skeletal Muscle Dysfunction With L-Carnitine for the Treatment of Patients With Chronic Obstructive Pulmonary Disease [0.03%]
L-肉毒碱靶向慢性阻塞性肺病患者的骨骼肌功能障碍治疗
Ba X Hoang,B O Han,William H Fang et al.
Ba X Hoang et al.
Chronic obstructive pulmonary disease (COPD) is a major medical problem and the world's third leading cause of death. COPD is a chronic disease with heterogeneous clinical symptoms, disease progression, and treatment responses. Besides pulm...
The Decline of Cortical Beta Oscillation on the Function of Eye-hand Coordination in the Healthy Elderly [0.03%]
皮层beta振荡的下降对健康老年人眼手协调功能的影响
Rodiya Manor,Dania Cheaha,Enoch Perimal et al.
Rodiya Manor et al.
Background/aim: There seems to be a correlation between changes in movement patterns with aging and brain activation. In the preparation and execution of movements, neural oscillations play an important role. In this stud...
Benefit Over Risk Assessment of CT-guided Lung Core Needle Biopsy With the Coaxial Technique [0.03%]
CT引导下应用同轴技术进行经皮肺穿刺活检的风险与效益评估
Giulio Barbiero,Michele Battistel,Alessandro Pauro et al.
Giulio Barbiero et al.
Background/aim: Lung percutaneous needle biopsy (PNB) under CT guidance can be performed with a single-needle or with a coaxial (CX) technique. This study evaluated the CX technique in a large cohort of patients who under...
The Soluble Lectin Families as Novel Biomarkers for COVID-19 Pneumonia [0.03%]
可溶性凝集素家族作为新型冠状病毒肺炎的新型生物标志物
Haruka Takenaka,Atsushi Saito,Koji Kuronuma et al.
Haruka Takenaka et al.
Background/aim: The lung-specific soluble lectins, SP-A and SP-D have been clinically used to diagnose interstitial lung disease, but their clinical significance in COVID-19 remains controversial. This study was undertake...
Choline-deficient Diet-induced NAFLD Animal Model Recaptures Core Human Pathophysiology With Similar Gene Co-expression Networks [0.03%]
无胆碱饮食诱导的非酒精性脂肪肝病动物模型具有类似人类核心病理生理过程及基因共表达网络
Tatsuya Ishigure,Tomohiko Sasase,Marika Tohma et al.
Tatsuya Ishigure et al.
Background/aim: Nonalcoholic fatty liver disease (NAFLD) is a wide spectrum of liver disorders ranging from simple steatosis to nonalcoholic steatohepatitis, cirrhosis, and hepatocellular carcinoma. Recently, the prevalen...
Role of Reduced Bdnf Expression in Novel Apc Mutant Allele-induced Intestinal and Colonic Tumorigenesis in Mice [0.03%]
Bdnf表达降低在Apc新突变等位基因诱导的小鼠肠道和结肠肿瘤发生中的作用
Ayşenur Gok,Aynur Işik,Sinem Bakir et al.
Ayşenur Gok et al.
Background/aim: Brain-derived neurotrophic factor (BDNF) is a growth factor of the neurotrophin family. Recent studies indicate that its expression is regulated by Wnt/β-catenin signaling. In this study, we aimed to exam...
The EGF Motif With CXDXXXXYXCXC Sequence Suppresses Fibrosis in a Mouse Skin Wound Model [0.03%]
具有CXDXXXXYXCXC序列的EGF motif通过抑制瘢痕形成促进伤口愈合
Hisataka Kitano,Tomomi Ishikawa,Yoh Masaoka et al.
Hisataka Kitano et al.
Background/aim: Fibrosis is an essential process for wound healing, but excessive fibrosis, such as keloids and hypertrophic scars, can cause cosmetic and functional problems. These lesions are caused by abnormal depositi...
Dietary Intake of Polyunsaturated Fatty Acids and Diabetic Nephropathy: Cohort Analysis of the Tsugaru Study [0.03%]
多不饱和脂肪酸的摄入与糖尿病肾病的关系：古沙鲁研究中的队列分析
Norio Nakamura,Daiki Nagawa,Masamichi Nakata et al.
Norio Nakamura et al.
Background/aim: Diabetic nephropathy (DN) is the leading cause of end-stage renal failure and its incidence continues to increase. To decrease this, a countermeasure from an early stage is required. This is a DN stage 2 o...