Advanced Cholangiocarcinoma With High Tumor Mutation Burden Achieving Complete Response to Immune Check Point Inhibitor [0.03%]
高肿瘤突变负荷的进展期胆管癌对免疫检查点抑制剂治疗获得完全缓解
Hirohisa Okabe,Toshiro Masuda,Hidetoshi Nitta et al.
Hirohisa Okabe et al.
Background/aim: Genomic examination of tumor tissue has been clinically accepted, and the identification of actionable mutations for molecular-targeted therapy may provide substantial survival benefit for patients with ad...
Return to Work After Breast Cancer Treatment: An Electronic Health Record-based Study in North Norway [0.03%]
基于电子健康记录的挪威北部乳腺癌患者治疗后的复工研究
Carsten Nieder,Ellinor C Haukland,Bård Mannsåker
Carsten Nieder
Background/aim: Breast cancer treatment may interfere with work ability. Previous return-to-work studies have often focused on participants who were invited to participate after treatment completion. Participation varied,...
First Clinical Safety and Feasibility Data of Whole-body Hyperthermia Pressurized Intraperitoneal Aerosol Chemotherapy (WBH-PIPAC) for Peritoneal Surface Malignancies [0.03%]
全身影像导引区域性腹腔加温高压雾化化疗(PIPAC)治疗腹膜表面恶性肿瘤的首次临床安全及可行性数据
Fabian Kockelmann,Urs Giger-Pabst,Mehdi Ouaissi et al.
Fabian Kockelmann et al.
Background/aim: This study evaluated the feasibility and safety of whole-body hyperthermia pressurized intraperitoneal aerosol chemotherapy (WBH-PIPAC) in patients with peritoneal surface malignancies. ...
Comparison of Real-world Efficacy and Safety of Atezolizumab and Durvalumab in Combination With Chemotherapy for First-line Treatment of Extensive-stage Small-cell Lung Cancer [0.03%]
阿特珠单抗和度伐利尤单抗联合化疗一线治疗广泛期小细胞肺癌真实世界疗效和安全性的对比研究
Fumiyasu Igata,Hiroyuki Inoue,Takato Ikeda et al.
Fumiyasu Igata et al.
Background/aim: The combination of programmed cell death ligand 1 inhibitors and platinum-based chemotherapy has become the standard treatment for first-line therapy in extensive-stage small-cell lung cancer (ES-SCLC). Th...
Comparative Study
Anticancer research. 2024 Jul;44(7):3175-3183. DOI:10.21873/anticanres.17132 2024
hMAGEA2 Accelerates the Progression of Prostate Cancer via the EFNA3-Erk1/2 Signaling Pathway [0.03%]
HMAGEA2通过EFNA3-Erk1/2信号通路促进前列腺癌进展
Sehyeon Han,Soyoung Jang,Seoung-Woo Lee et al.
Sehyeon Han et al.
Background/aim: Human melanoma-associated antigen A2 (hMAGEA2) family members play several roles in many types of cancer and have been explored as potential prognostic markers. In this study, we investigated the molecular...
Mesna, Doxorubicin, Ifosfamide and Dacarbazine (MAID) Combination Chemotherapy for Retroperitoneal Sarcoma: A Single-center Experience [0.03%]
美司钠、多柔比星、异环磷酰胺和达卡巴嗪(MAID)联合化疗治疗腹膜后肉瘤：一项单中心经验研究报告
Yudai Ishiyama,Toru Inakawa,Maki Yoshino et al.
Yudai Ishiyama et al.
Background/aim: There is limited evidence regarding the systemic treatment of retroperitoneal soft-tissue sarcoma, and the current Japanese guidelines fail to make definitive suggestions. Here, we report our experience wi...
Exosomal miR-141-3p Induces Gemcitabine Resistance in Biliary Tract Cancer Cells [0.03%]
外泌体miR-141-3p通过靶向ZC3H13诱导胆道癌细胞吉西他滨耐药性
Akihiro Tokuhisa,Ryouichi Tsunedomi,Yuta Kimura et al.
Akihiro Tokuhisa et al.
Background/aim: Gemcitabine (GEM)-based chemotherapy has been established as the core multimodal therapy for biliary tract cancer (BTC). However, the prognosis of BTC is unfavorable because of its resistance to GEM. Exoso...
A Retrospective Analysis of Systemic Oncologic Treatment in Older Patients With Advanced Soft-tissue Sarcoma [0.03%]
老年晚期软组织肉瘤患者全身抗肿瘤治疗的回顾性分析
Jasmiini Lemma,Jasmin Liljeström,Mika Sampo et al.
Jasmiini Lemma et al.
Background/aim: Almost half of all patients with soft-tissue sarcoma are over 65 years of age, and the proportion of older patients is increasing. Despite this, they have been underrepresented in clinical trials and only ...
Clinical Value of Fine Needle Aspiration Cytology and Core Needle Biopsy in Head and Neck Pathology - A Nationwide Survey in Germany [0.03%]
德国全国范围内的头颈部病理细针抽吸细胞学和空心针活检临床价值调查
Urban W Geisthoff,Freya Droege,Catherine Hand et al.
Urban W Geisthoff et al.
Background/aim: Fine-needle aspiration cytology (FNA) and core needle biopsy (CNB) of the thyroid gland, salivary glands, and lymph nodes are considered simple and rapid methods for minimally invasive tissue collection. W...
Clinical Association Between Immune-related Adverse Events and Treatment Efficacy in Patients With Non-small-cell Lung Cancer Treated With Nivolumab-Ipilimumab-based Therapy [0.03%]
纳武单抗-伊匹木单抗方案治疗非小细胞肺癌患者疗效与免疫相关不良事件的临床分析
Noriyuki Ebi,Hiroyuki Inoue,Fumiyasu Igata et al.
Noriyuki Ebi et al.
Background/aim: Nivolumab and ipilimumab combination therapy has been extensively explored for the treatment of advanced non-small-cell lung cancer (NSCLC) through the pivotal phase III trials CheckMate 227 and CheckMate ...