Correlation Between Blood Levels of Cysteine Protease Caspase-1 (Casp1) and Pain Scores (NRS) Post-surgery: A Prospective Randomized Study of Patients With Cholelithiasis [0.03%]
胱天蛋白酶-1(Casp1)血液水平与胆石症术后疼痛评分(NRS)相关性：一项前瞻性随机研究
Maaret Eskelinen,Tuomas Selander,Jukka Pulkkinen et al.
Maaret Eskelinen et al.
Background/aim: Cysteine protease caspase-1 (Casp1) plays a crucial role in the conversion of pro-cytokines to active cytokines (CYTs). The purpose of this work was to determine Casp1 blood levels in a cohort of 114 chole...
Randomized Controlled Trial
Anticancer research. 2024 Jul;44(7):2997-3003. DOI:10.21873/anticanres.17112 2024
Tumor Infiltrating Effector Regulatory T Cells Express VEGF Receptor 2 in Patients With Colorectal Cancer [0.03%]
结直肠癌患者的肿瘤浸润效应调节性T细胞表达VEGF受体2
Hideaki Tsumuraya,Kosaku Mimura,Shotaro Nakajima et al.
Hideaki Tsumuraya et al.
Background/aim: Regulatory T cells (Tregs) suppress various anti-tumor immune responses in the tumor microenvironment (TME) and their control is considered essential to enhancing efficacy of cancer immunotherapy. The purp...
ALK Inhibitor and Chemotherapy Combinations in Models of ALK-Translocated NSCLC [0.03%]
用于ALK重排的NSCLC模型中的ALK抑制剂与化疗联合治疗
Milla E K Luukkainen,Jussi P Koivunen
Milla E K Luukkainen
Background/aim: Randomized trials have shown the benefit of combining tyrosine kinase inhibitors (TKI) and chemotherapy in the treatment of epidermal growth factor receptor-mutant non-small-cell lung cancer (NSCLC). For a...
Comparative Analysis of Clinical Characteristics and Prognosis Between Primary Lung Cancers Identified as Screening Detected and Incidentally Detected Pulmonary Nodules [0.03%]
筛查发现与偶然发现肺结节的原发性肺癌的临床特征和预后比较分析
Sungmin Zo,Chohee Kim,Ho Yun Lee et al.
Sungmin Zo et al.
Background/aim: Although the importance of low-dose computed tomography (LDCT) screening is increasingly emphasized and implemented, many lung cancers continue to be incidentally detected during routine medical practices,...
Comparative Study
Anticancer research. 2024 Jul;44(7):3163-3173. DOI:10.21873/anticanres.17131 2024
Ramucirumab Beyond Disease Progression After Paclitaxel Plus Ramucirumab in Gastric Cancer: A Phase II Trial [0.03%]
一线帕利珠单抗联合白蛋白结合型紫杉醇之后继用 ramucirumab 治疗胃癌的 II 期临床研究
Yasuyoshi Sato,Hiroharu Yamashita,Koichi Yagi et al.
Yasuyoshi Sato et al.
Background/aim: Irinotecan monotherapy was the most widely used third-line chemotherapy for unresectable advanced or recurrent gastric cancer in Japan until the approval of nivolumab in September 2017 and trifluridine/tip...
Clinical Trial
Anticancer research. 2024 Jul;44(7):3125-3131. DOI:10.21873/anticanres.17126 2024
Extracellular Vesicle DNA Extraction and Sequencing in Ancient Serum Samples From Patients With Breast Cancer [0.03%]
从乳腺癌患者古代血清样本中提取外泌体DNA并进行测序
Martin Heidinger,Daniel Egle,Salvatore Piscuoglio et al.
Martin Heidinger et al.
Background/aim: Extracellular vesicle DNA (EV-DNA) has emerged as a novel biomarker for tumor mutation detection using liquid biopsies, exhibiting biological advantages compared to cell-free DNA (cfDNA). This study assess...
Comparative Study on the Clinicopathologic and Molecular Characteristics of Primary and Secondary Diffuse Large B-cell Lymphoma in the Central Nervous System [0.03%]
原发和继发中枢神经系统弥漫大B细胞淋巴瘤的临床病理及分子特征比较研究
Jeongeun DO,Leonard N Yenwongfai,Sung-Im DO et al.
Jeongeun DO et al.
Background/aim: Diffuse large B-cell lymphoma of the central nervous system (CNS-DLBCL) is an aggressive B-cell lymphoma with clinical and molecular heterogeneity. Primary CNS-DLBCL (PCNSL) affects the brain, eyes, leptom...
Comparative Study
Anticancer research. 2024 Jul;44(7):2953-2960. DOI:10.21873/anticanres.17107 2024
Analysis of Treatment Response With Proteins Related to Tumor Immunity in Postoperative Irradiated Cervical Cancer Patients [0.03%]
分析术后放疗的宫颈癌患者中与肿瘤免疫相关的蛋白对治疗反应的影响
Shoh Mafune,Masanori Someya,Tomokazu Hasegawa et al.
Shoh Mafune et al.
Background/aim: This study evaluated the association between programmed cell death-ligand 1 (PD-L1) and prognosis in patients with cervical cancer treated with postoperative radiation and the impact of neoadjuvant chemoth...
A Flexible Semi-automated Assay for Assessing Radiation-sensitization and Toxicity in the Mouse Intestine [0.03%]
一种评估辐射敏感性和毒性的小鼠肠道灵活半自动化测定法
Anam Nan Nan Liu,Jennifer Hazel Elizabeth Baker,Alastair Hugh Kyle et al.
Anam Nan Nan Liu et al.
Background/aim: The aim of this study was to develop an enhanced intestinal toxicity assay with three outputs assessing proliferation, villi morphology and DNA damage after irradiation. ...
Autologous Peripheral Blood Stem Cell Transplantation and Timing of Local Radiation Therapy in Patients With Malignant Lymphoma: Results of the Japanese Radiation Oncology Study Group Questionnaire Survey [0.03%]
日本放射肿瘤学会调查问卷结果：自体外周血干细胞移植和恶性淋巴瘤局部放射治疗的时间关系研究
Naoya Ishibashi,Yasuo Ejima,Toshinori Soejima et al.
Naoya Ishibashi et al.
Background/aim: Malignant lymphoma (ML) including Hodgkin's lymphoma and non-Hodgkin's lymphoma is often treated with local radiation therapy (RT) in combination with autologous hematopoietic stem cell transplantation (AS...