Membrane Formed Around Liquid Nitrogen-treated Bone Promotes Osteogenesis and Revitalization in a Rat Model [0.03%]
液氮处理骨表面形成的薄膜促进成骨和活化作用小鼠模型研究
Yohei Asano,Norio Yamamoto,Katsuhiro Hayashi et al.
Yohei Asano et al.
Background/aim: This study aimed to investigate the structure and functions of the membrane formed around liquid nitrogen-treated bones in the osteogenesis and revitalization of frozen bone using a rat model. ...
Risks and Outcomes of Early Dose Reduction in Adjuvant CAPOX Therapy for Colorectal Cancer [0.03%]
结直肠癌辅助化疗卡培他滨早期减量的风险和结局分析
Ikuma Shioi,Hiroomi Ogawa,Ryozan Naito et al.
Ikuma Shioi et al.
Background/aim: Adjuvant capecitabine and oxaliplatin (CAPOX) therapy is standard strategy for colorectal cancer with risk of recurrence. Early dose reduction (EDR) of CAPOX therapy is commonly used in real-world practice...
Predictive Factors for Early Biochemical Recurrence Following Robot-assisted Radical Prostatectomy [0.03%]
机器人辅助根治性前列腺切除术后早期生化复发的预测因素分析
Kensuke Mitsunari,Hajime Fukushima,Hiroki Kurata et al.
Kensuke Mitsunari et al.
Background/aim: The primary objective of this study was to identify predictors for biochemical recurrence (BCR) within 2 years following robot-assisted radical prostatectomy (RARP). Identifying predictors will enable insi...
Prognostic Factors for Progression-free Survival and Overall Survival After Recurrence of Glioblastoma [0.03%]
复发胶质母细胞瘤患者无进展生存期和总生存期的预后因素分析
Oksana Zemskova,Nathan Y Yu,Jan Leppert et al.
Oksana Zemskova et al.
Background/aim: Many patients with glioblastoma experience an intracerebral recurrence and require a personalized treatment. This study aimed to facilitate this approach by identifying prognostic factors for progression-f...
Current Status of Conversion Hepatectomy After Sorafenib and Lenvatinib Treatment for Unresectable Hepatocellular Carcinoma [0.03%]
索拉非尼和仑伐替尼治疗后的不可切除肝细胞癌转化为可切除肝切除的现状
Shohei Komatsu,Yoshihiko Yano,Takuya Mimura et al.
Shohei Komatsu et al.
Background/aim: Sorafenib and lenvatinib have long been used as a first-line treatment for advanced hepatocellular carcinoma (HCC). Along with the development of systemic chemotherapy for HCC, the concept of conversion he...
Yuki Uemichi,Miyuki Mabuchi,Natsumi Tsuchiya et al.
Yuki Uemichi et al.
Background/aim: Glioblastoma is an incurable cancer with limited treatment options and a low survival rate. Temozolomide is the standard marketed small-molecule agent for glioblastoma therapy; therefore, we aimed to find ...
Impact of Novel Agents on Patient Characteristics, Treatment Patterns, and Outcomes in Patients With Metastatic Castration-resistant Prostate Cancer [0.03%]
新型药物对转移性去势抵抗性前列腺癌患者特征、治疗模式和结局的影响
Yutaka Yamamoto,Mituhisa Nishimoto,Yasunori Akashi et al.
Yutaka Yamamoto et al.
Background/aim: The therapeutic landscape for metastatic castration-resistant prostate cancer (mCRPC) has changed dramatically with the introduction of several novel agents. However, limited data are available to determin...
Prophylactic Effect of Clarithromycin on Radiation Pneumonitis in IMRT for Lung Cancer [0.03%]
克拉霉素预防肺癌调强放疗放射性肺炎的疗效观察
Takayuki Ohguri,Takahiro Morisaki,Hirohide Itamura et al.
Takayuki Ohguri et al.
Background/aim: To evaluate the association between prophylactic administration of clarithromycin (CAM) and the development of radiation pneumonitis (RP) in patients treated with intensity modulated radiation therapy (IMR...
Association of BRAF or TERT Promoter Mutations and Advanced Papillary Thyroid Carcinoma [0.03%]
BRAF或TERT启动子突变与进展性乳头状甲状腺癌的关系
Soji Toda,Nao Saito,Mei Kadoya et al.
Soji Toda et al.
Background/aim: BRAF and TERT promoter mutations are associated with the poor prognosis of papillary thyroid carcinoma. This single-center retrospective study investigated the influence of these genes on advanced cases. ...
Kaempferol Inhibits Cervical Cancer Cells by Inducing Apoptosis and Autophagy via Inactivation of the PI3K/AKT/mTOR Signaling Pathway [0.03%]
山柰酚通过抑制PI3K/AKT/mTOR信号通路诱导宫颈癌细胞凋亡和自噬抗氧化应激保护神经元免受缺血伤害的研究进展
Eun-Young Choi,Eun-Ji Han,Su-Ji Jeon et al.
Eun-Young Choi et al.
Background/aim: Kaempferol, a natural flavonoid, occurs abundantly in fruits and vegetables. It has various bioactivities, with antioxidant, anti-inflammatory, and other beneficial properties. The aim of this study was to...