Clinicopathological Study of Resected and Recurrent Cases of Intrahepatic Intraductal Papillary Neoplasm of the Bile Duct [0.03%]
可切除和复发的肝内胆管乳头状黏液性肿瘤的临床病理研究
Shoichiro Arai,Hisamune Sakai,Masanori Akashi et al.
Shoichiro Arai et al.
Background/aim: This study aimed to characterize intraductal papillary neoplasm of the bile duct (IPNB) in patients undergoing initial and recurrent surgical resection and to evaluate the appropriateness of surgical treat...
Interactive Analysis of UTX-114 Family With EGFR-tyk: Molecular Features of Acetyl Glycosylated Gefitinib [0.03%]
UTX-114族与EGFR-酪氨酸激酶：吉非替尼乙酰基糖基化分子特征的交互式分析
Kazuto Ohkura,Atsushi Tabata,Yoshihiro Uto
Kazuto Ohkura
Background/aim: Acetyl glucose adducts (UTX-114, -115, and -116) were prepared from gefitinib, and their characteristics (e.g., anticancer activity, structural property) were analyzed. ...
A Bridge to Curative Surgery for Obstructive Colorectal Cancer: Self-expandable Metallic Stent Versus Decompression Tube [0.03%]
结肠癌急性梗阻的桥梁治疗手段：金属支架与双套管引流的经验比较研究
Hiroyuki Takahashi,Daibo Kojima,Hideo Wada et al.
Hiroyuki Takahashi et al.
Background/aim: Self-expandable metallic stent (SEMS) placement is becoming the standard bridge-to-surgery (BTS) strategy for potentially curable left-sided obstructive colorectal cancer (OCRC). The study objective was to...
Comparative Study
Anticancer research. 2024 Aug;44(8):3427-3441. DOI:10.21873/anticanres.17163 2024
Knockdown of CDX2 Induces microRNA-221 Up-regulation in Human Colon Cancer Cells [0.03%]
CDX2基因沉默通过上调microRNA-221诱导结肠癌细胞恶性表型的改变
Junko Mukohyama,Minori Koizumi,Kimihiro Yamashita et al.
Junko Mukohyama et al.
Background/aim: Caudal-type homeobox transcription factor 2 (CDX2) is a master regulator of intestinal development and maintenance of the intestinal epithelium. We previously revealed that CDX2Low colorectal cancers (CRCs...
Spatial Transcriptomic Profiling Reveals Gene Expression Characteristics in Lymph Node-positive Breast Carcinoma [0.03%]
空间转录组学分析揭示了淋巴结阳性乳腺癌的基因表达特征
Yumin Chung,Jinah Chu,Sung-Im DO et al.
Yumin Chung et al.
Background/aim: Studies on the differences in gene expression characteristics according to lymph node metastasis in breast carcinoma are lacking. This study aimed to compare the spatially resolved transcriptomic profiles ...
Prognostic Significance of 18F-FDG PET/CT and Tumor Metabolic Changes in Patients With Pancreatic Ductal Adenocarcinoma [0.03%]
18F-FDG PET/CT及肿瘤代谢变化在胰腺导管腺癌中的预后价值
Ayaka Shimomura,Minoru Oshima,Hironobu Suto et al.
Ayaka Shimomura et al.
Background/aim: 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) is reportedly associated with the malignant potential of cancer. This study aimed to evaluate the association between FD...
Pimitespib, a Novel Heat Shock Protein 90 Inhibitor, Is Effective in Treating Renal Cell Carcinoma by Anti-angiogenetic Signaling [0.03%]
新型HSP90抑制剂Pimitespib通过抗血管生成信号途径有效治疗肾细胞癌
Ryugo Teranishi,Tsuyoshi Takahashi,Yukinori Kurokawa et al.
Ryugo Teranishi et al.
Background/aim: Most clear cell renal cell carcinomas (ccRCCs) have a dysfunctional von Hippel-Lindau tumor suppressor protein (VHL). Hypoxia-inducible factors 1 and 2 alpha (HIF1α and HIF2α) accumulate in ccRCC with dy...
Tranilast Inhibits TRPV2 and Suppresses Fibrosis Progression and Weight Gain in a NASH Model Mouse [0.03%]
トラニラスタ通过抑制TRPV2抑制NASH模型小鼠的纤维化进展和体重增加
Takahiro Nagata,Satoshi Shakado,Eri Yamauchi et al.
Takahiro Nagata et al.
Background/aim: This study aimed to investigate the role of transient receptor potential vanilloid 2 (TRPV2) in a mouse model with non-alcoholic steatohepatitis (NASH) and to examine the effects of tranilast on TRPV2 and ...
A Multidisciplinary Therapeutic Approach Proposal for Huge Hepatocellular Carcinomas Exceeding 10 cm in Diameter [0.03%]
一种针对直径超过10厘米的巨大肝细胞癌的多学科治疗方案建议
Yuichi Goto,Takashi Niizeki,Hisamune Sakai et al.
Yuichi Goto et al.
Background/aim: The outcome of hepatectomy for a hepatocellular carcinoma (HCC) exceeding 10 cm (i.e., huge HCC) remains unfavorable. The aim of the current study was to evaluate the optimal therapeutic approach for huge ...
Brief Pain Inventory (BPI) Pain Survey Versus Cysteine Protease Caspase-1 (Casp1) Blood Levels Following Midline Laparotomy: A Prospective Randomized Study of Patients With Benign Disease and Patients With Cancer [0.03%]
中线开腹术后简易疼痛量表与半胱氨酸蛋白酶caspase-1（casp1）血药浓度对比研究：良性疾病和恶性肿瘤患者的前瞻性随机研究
Maaret Eskelinen,Tuomas Selander,Iina Saimanen et al.
Maaret Eskelinen et al.
Background/aim: There is lack of studies assessing the correlation between pain scales and acute phase immune response (APR) following surgery. The purpose of this work was to assess the correlation between cysteine prote...
Randomized Controlled Trial
Anticancer research. 2024 Aug;44(8):3463-3471. DOI:10.21873/anticanres.17166 2024