Marked Palliative Benefits Seen With Treatment of Very Advanced Breast Cancer With the Progesterone Receptor Modulator Mifepristone [0.03%]
抗孕激素米非司酮治疗晚期乳腺癌获益明显
Jerome H Check,Diane L Check,Naomi Ganpo-Nkewnkwa
Jerome H Check
Background/aim: Treatment of cancers known to be positive for the nuclear progesterone receptor (nPR), e.g., breast, ovarian, and endometrial cancers with PR modulators/antagonists, e.g., mifepristone, have not shown impr...
Neck Dissection and Immune Checkpoint Inhibitor Efficacy in Head and Neck Cancer: A Retrospective Study [0.03%]
颈部淋巴清扫术与头颈癌免疫检查点抑制剂疗效之间的关系：一项回顾性研究
Yoh-Ichiro Iwasa,Kentaro Hori,Yoh Yokota et al.
Yoh-Ichiro Iwasa et al.
Background/aim: T-cell priming within tumor-draining lymph nodes (TDLNs) is essential for optimal immune checkpoint inhibitor (ICI) activity. Because neck dissection (ND) removes cervical lymph nodes that may function as ...
The Usefulness of the Modified Controlling Nutritional Status Score for Assessing Prognosis in Patients With Colorectal Cancer [0.03%]
改良的营养状况评分在结直肠癌患者预后评估中应用价值分析
Hideki Tanda,Masatsune Shibutani,Yuki Seki et al.
Hideki Tanda et al.
Background/aim: The Controlling Nutritional Status (CONUT) score, calculated using the serum albumin level, total cholesterol level (T-cho), and peripheral lymphocyte count, is a widely accepted prognostic marker for colo...
Clinical Relevance of the CALLY Index in Prognostic Stratification of Intrahepatic Cholangiocarcinoma [0.03%]
CALLY指数在肝内胆管癌预后分层中的临床意义
Satoshi Matsui,Yoshiyasu Kato,Katsuhisa Ohgi et al.
Satoshi Matsui et al.
Background/aim: Recent investigations have highlighted the prognostic significance of the C-reactive protein-albumin-lymphocyte (CALLY) index across various malignancies. However, its prognostic relevance in patients with...
Geographic Variations in Demographics, Socioeconomic Status, and Stage at Diagnosis Among Hormone Receptor-positive Invasive Ductal Carcinoma: An NCDB Analysis (2004-2020) [0.03%]
激素受体阳性浸润性导管癌的地理差异：基于NCDB数据库（2004-2020）的分析
Berkay Demirors,Syeda Hoorulain Ahmed,Karen Grace et al.
Berkay Demirors et al.
Background/aim: Although hormone receptor-positive (HR+) invasive ductal carcinoma (IDC) is the most common breast cancer subtype, there is limited evidence describing how demographic and clinical features vary across U.S...
Over-expression of Anillin Actin Binding Protein in Adrenocortical Carcinoma Tissues Is Associated With Poorer Prognosis of Patients [0.03%]
肾上腺皮质癌组织中Anillin肌动蛋白结合蛋白过表达与患者预后不良有关
Shin-Nosuke Yamashita,Yoshiatsu Tanaka,Shajedul Islam et al.
Shin-Nosuke Yamashita et al.
Background/aim: Adrenocortical carcinoma (ACC) is a rare adrenal cortex cancer (0.7-2.0 cases per million) with high malignancy and poor prognosis (5-year survival
Polymorphisms of FGFR Pathway-related Factors and Capecitabine-induced Hand-foot Syndrome in Japanese Patients With Colorectal Cancer [0.03%]
表皮生长因子受体通路相关因素的多态性与日本人结直肠癌患者卡培他滨所致手足综合症的关系研究
Riku Yamanaka,Natsumi Matsumoto,Remi Murase et al.
Riku Yamanaka et al.
Background/aim: Hand-foot syndrome (HFS) is a common adverse event associated with capecitabine. While the fibroblast growth factor receptor (FGFR) signaling pathway is involved in skin wound healing, its essential role i...
Postmenopausal Stage IV Ovarian Yolk Sac Tumor With Neuroendocrine Features: Report of a Rare Case [0.03%]
绝经后卵巢卵黄囊瘤伴神经内分泌特征的IV期病例报告
Stefano Fucina,Lucia Lerda,Michele Bartoletti et al.
Stefano Fucina et al.
Background/aim: Ovarian yolk sac tumors (YSTs) are highly uncommon in postmenopausal women and may show unusual morphological patterns, including neuroendocrine differentiation. Such presentations are exceptionally rare a...
The miR-29b Byproduct MIRTX Shows Superior Anti-tumor Activity, Compared to miR-29b-3p, in Pancreatic Cancer Cells [0.03%]
与miR-29b-3p相比，miR-29b副产物MIRTX在胰腺癌细胞中显示出更强的抗肿瘤活性
Yuhki Yokoyama,Akira Inoue,Hiroyuki Yamamoto et al.
Yuhki Yokoyama et al.
Background/aim: Pancreatic cancer has a poor prognosis, with a 5-year survival rate of only 9%. Thus, there is an urgent need to develop effective cancer therapeutics for this disease. It is expected that nucleic acid the...
Pan-Cancer Landscape of CDK1 Uncovers Its Potential Prognostic Significance and Therapeutic Targeting in Adrenocortical Carcinoma [0.03%]
泛癌症中的CDK1全景图揭示了其在肾上腺皮质癌预后判断和治疗中的潜在作用
Mohd Rehan,Firoz Ahmed,Mohd Suhail et al.
Mohd Rehan et al.
Background/aim: Cyclin-dependent kinase 1 (CDK1) is a regulator of the G2-M transition whose dysregulation undermines cell-cycle fidelity and drives malignant growth. Although CDK1 has been implicated in tumorigenesis, it...