Analysis of Clinical Benefit Using DNG64- CAR-V Chimeric Tumor Targeted Amphotropic RNA Vector in CCNG1 Expressing Cancers [0.03%]
分析CCNG1阳性肿瘤应用DNG64-CAR-V泛素嗜性RNA载体临床治疗效益
Sant P Chawla,Samantha Jeffrey,Skyler S Pang et al.
Sant P Chawla et al.
Background/aim: Metastatic cancer is almost always fatal, with few promising clinical options. DNG64-CAR-V is an off-the-shelf, replication-incompetent Chimeric Amphotropic tumor-targeted RNA Vector encoding a cytocidal C...
Tenofovir Alafenamide Promotes Differentiation and Induces Apoptosis of AML Cells by Inhibiting Telomerase Reverse Transcriptase [0.03%]
替诺福韦阿拉芬酰胺通过抑制端粒酶逆转录酶促进急性髓系白血病细胞分化和凋亡
Ji-Eun Lee,Byeol-Eun Jeon,Chan-Seong Kwon et al.
Ji-Eun Lee et al.
Background/aim: Acute myeloid leukemia (AML) is the most common type of leukemia in adults. However, patient prognosis remains poor despite advances in our understanding of its molecular cytogenetics and pathogenesis. Dif...
Clinical Outcomes of Proton Beam Therapy for Hepatocellular Carcinoma Adjacent to the Gastrointestinal Tract [0.03%]
质子治疗邻近胃肠道的肝细胞癌的临床结果分析
Yuzheng Zhou,Masaki Nakamura,Kenji Makita et al.
Yuzheng Zhou et al.
Background/aim: To minimize gastrointestinal (GI) toxicity, our institution implemented a treatment strategy during proton beam therapy (PBT) for hepatocellular carcinoma (HCC) located adjacent to the GI tract, in which t...
Allow Aloe to Do the Work: Aloe vera Constrains Growth of Bladder Cancer Cells and Modulates Expression of Key Costimulatory Molecules [0.03%]
让芦荟发挥作用吧：_aloe vera_ 可限制膀胱癌细胞增殖并调节关键协同刺激分子的表达
Arturo G Gutiu,Austin J Marrah,Brady B Voss et al.
Arturo G Gutiu et al.
Background/aim: Bladder cancer is one of the most common urological malignancies, with 5-year survival rates below 40% in advanced cases. Oncologic immunotherapy has become a popular approach to treating cancer and progra...
Phosphodiesterase 5 Inhibitor Sildenafil Inhibits HPV+ Cervical Cancer Cells and Cervical Cancer Stem Cells by Apoptotic Induction and Telomerase Activity Modulation [0.03%]
磷酸二酯酶5抑制剂西地那非通过诱导凋亡和端粒酶活性调节来抑制HPV阳性宫颈癌细胞和宫颈癌干细胞
Solanki Sarkar,Amrita Saha,Basabkanti DAS et al.
Solanki Sarkar et al.
Background/aim: Cervical cancer mortality has since long been associated with HPV positivity. However, emerging evidence points to the significant role of cancer stem cells (CSCs) in tumorigenesis, metastasis, relapse, an...
Balloon-occluded Infusion of Fragmented Gelatin Particles of Transarterial Embolization for Hypervascular Hepatic Metastases: A Prospective Trial [0.03%]
动脉灌注明胶颗粒栓塞治疗高血管肝转移癌的前瞻性研究
Sodai Hoshiai,Takeshi Yamada,Mariko Kobayashi et al.
Sodai Hoshiai et al.
Background/aim: Balloon-occluded infusion of fragmented gelatin particles of transarterial embolization (BOIG-TAE) is a chemotherapy-free technique combining selective balloon occlusion with gelatin particle embolization....
Transoral Robotic Surgery for High Grade Oropharyngeal Mucoepidermoid Carcinoma With Good Outcome and Preserved Oropharyngeal Functions [0.03%]
经口机器人手术治疗高级别粘膜囊肿癌并保留咽功能取得良好效果
Austin M Yu,Thomas R O&#x;Toole,Jinping Lai
Austin M Yu
Background/aim: Mucoepidermoid carcinoma (MEC) is a common malignant salivary gland tumor but rarely seen in the tonsil. Case report: W...
Real-world Analysis of Treatment Patterns, Clinical Outcomes, and Molecular Profiling in Advanced Biliary Tract Cancer [0.03%]
基于真实世界数据的晚期胆道癌治疗模式、临床结局和分子分型分析
Chung Ryul Oh,Jae Hyuk DO,Hyoung-Chul Oh et al.
Chung Ryul Oh et al.
Background/aim: Real-world data regarding the efficacy of immunotherapy and targeted agents in advanced biliary tract cancer (BTC) remain limited. We evaluated treatment patterns, outcomes, and molecular characteristics i...
P53-armed Oncolytic Adenovirus Enhances the Efficacy of PD-1 Blockade in Neuroblastoma by Inducing Immunogenic Cell Death [0.03%]
武装的p53溶瘤腺病毒通过诱导免疫原性细胞死亡增强神经母细胞瘤中PD-1阻断的效果
Morimichi Tani,Hiroshi Tazawa,Terutaka Tanimoto et al.
Morimichi Tani et al.
Background/aim: Neuroblastoma (NB) is a primary malignant tumor of the peripheral sympathetic nervous system. Although immunotherapy with immune checkpoint inhibitors (ICIs) targeting programmed cell death 1 (PD-1)/PD lig...
Impact of Postoperative Prognostic Nutritional Index on Post-gastrectomy Outcomes in Older Adults With Gastric Cancer [0.03%]
术后营养指数对老年胃癌患者胃切除术术后结果的影响
Kozo Miyatani,Tomoyuki Matsunaga,Hiroaki Saito et al.
Kozo Miyatani et al.
Background/aim: This study aimed to clarify the impact of preoperative and postoperative inflammation and nutritional markers on post-gastrectomy outcomes in older adult patients with gastric cancer (GC) using data from m...