Macroscopic Tumor Color as a Surrogate for Biological Diversity in Clear Cell Renal Cell Carcinoma [0.03%]
透明细胞肾细胞癌中肿瘤颜色作为生物学多样性的替代标志
Nozomi Tsujio,Chisato Ohe,Masanori Shiohara et al.
Nozomi Tsujio et al.
Background/aim: Clear cell renal cell carcinoma (ccRCC) exhibits marked intratumoral heterogeneity, reflected in its macroscopic color variation. As limited tissue sampling often underrepresents aggressive tumor component...
PD-1+Tim-3+CD103+ CD8+ Tumor-infiltrating Lymphocytes Are Associated With Favorable Outcomes in Colorectal Cancer [0.03%]
PD-1⁺Tim-3⁺CD103⁺ CD8⁺肿瘤浸润性淋巴细胞与结直肠癌预后良好相关
Daijiro Matoba,Takuro Saito,Takehiro Noda et al.
Daijiro Matoba et al.
Background/aim: Colorectal cancer (CRC) remains the leading cause of cancer-related mortality worldwide and necessitates the development of novel therapeutic strategies. The tumor immune microenvironment (TME) critically ...
Prognostic Relevance of FOS and JUN Family Members and Immune Cell Infiltration for the Survival of Patients With Ovarian Carcinoma [0.03%]
FOS和JUN家族成员及免疫细胞浸润对卵巢癌患者的预后价值
Mona Dawood,Ednah Ooko,Thomas Efferth et al.
Mona Dawood et al.
Background/aim: Ovarian carcinoma is a difficult-to-treat cancer. It is often resistant to chemotherapy and targeted therapy. The 5-year survival rates of patients with advanced tumors are usually below 40%. Immunotherapy...
Practical Implementation and Validation of Geriatric Assessment in Older Adults With Esophageal Cancer [0.03%]
老年食管癌患者姑息性评估的实践和验证
Tetsuro Kawazoe,Tomonori Nakanoko,Tomoya Harima et al.
Tetsuro Kawazoe et al.
Background/aim: Esophageal squamous cell carcinoma (ESCC) is associated with poor prognosis, and older adults frequently present with frailty and comorbidities that complicate multimodal treatment. Although international ...
BIT1 as an Effector of EGFR-TKI-induced Apoptosis via TLE1 Inhibition in Lung Adenocarcinoma Cells [0.03%]
TLE1抑制剂BIT1在肺癌腺癌细胞中的作用及其诱导凋亡机制研究
Ma Carmela Dela Cruz,Xin Yao,Alajah Nealy et al.
Ma Carmela Dela Cruz et al.
Background/aim: Acquired resistance to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) remains a substantial clinical obstacle in treating lung adenocarcinoma (LUAD). Identifying pro-survival pat...
Usefulness of Artificial Intelligence for Surgical Support in Robot-assisted Distal Pancreatectomy: A Preliminary Case Report [0.03%]
机器人辅助远端胰腺切除术外科支持人工智能有用性的初步病例报告
Kazuhiro Matsuda,Takeshi Aoki,Nao Kobayashi et al.
Kazuhiro Matsuda et al.
Background/aim: The incidence of postoperative complications in minimally-invasive surgery for pancreatic disease remains a concern. The application of artificial intelligence (AI) in surgery has been reported to improve ...
Feasibility of Elastography for Preoperative Prediction of Malignancy of Gastrointestinal Stromal Tumor of the Stomach [0.03%]
弹性成像预测胃肠道间质瘤恶性程度的可行性研究
Motohira Yoshida,Taro Oshikiri,Satoshi Kikuchi et al.
Motohira Yoshida et al.
Background/aim: There are several well-known classifications for determining the grade of malignancy of gastrointestinal stromal tumor (GIST), but these classifications depend exclusively on invasive methods, including bi...
PKF118-310 as a Potential Small Molecule Inhibitor Targeting the Wnt/β-Catenin Pathway for Gastric Cancer Therapy [0.03%]
PKF118-310有望成为胃癌治疗的靶向Wnt/β-catenin信号通路的小分子抑制剂
Te-Sheng Chang,Chin Li,Wei-Ming Chen et al.
Te-Sheng Chang et al.
Background/aim: Gastric cancer (GC) remains a major public health concern both in Taiwan and worldwide. While advances in public health have reduced its incidence rate, clinical outcomes of advanced GC remain suboptimal w...
Impact of Reconstruction Type and Pancreatic Atrophy on Glycemic Variability After Distal Gastrectomy [0.03%]
术后血糖变异性的预测因素分析
Keiji Nishibeppu,Takeshi Kubota,Hiroyuki Inoue et al.
Keiji Nishibeppu et al.
Background/aim: Pancreatic atrophy commonly develops after gastrectomy and may contribute to postoperative metabolic disorders. However, the relationship between pancreatic volume (PV) reduction and glycemic variability (...
The Role of MRI in the Preoperative Staging of Rectal Cancer: Ten-year Experience from a Single Tertiary Center [0.03%]
磁共振成像在直肠癌术前分期中作用的十年单中心经验
Ariella Edina Kondor,András Vereczkei,Péter Varga et al.
Ariella Edina Kondor et al.
Background/aim: Accurate preoperative staging of rectal cancer (CRC) guides treatment decisions, particularly regarding neoadjuvant chemoradiotherapy. Although magnetic resonance imaging (MRI) is recommended for local sta...