Profiling of Lysine Lactylation Reveals Its Proliferation-promoting Functions in Colorectal Cancer Cells [0.03%]
组蛋白精氨酸瓜氨酸化修饰与结直肠癌增殖和转移的关系及机制研究
Zaikui Zhang,Haixia Tu,Zhongyan Han et al.
Zaikui Zhang et al.
Background/aim: Tumor cells generate energy through glycolysis and produce lactate as a byproduct. The lactate can be used as a substrate for lysine lactylation (Kla), a post-translational modification that may contribute...
Recurrence and Malignant Transformation After Borderline Ovarian Tumors: A Systematic Review and Meta-analysis [0.03%]
上皮性交界型卵巢肿瘤术后复发和癌变的系统评价和meta分析
Angeliki Taniskidi,Evangelia Giannas,Sofia Lekka et al.
Angeliki Taniskidi et al.
Background/aim: Borderline ovarian tumours (BOTs) frequently affect women of reproductive age. Fertility-sparing surgery (FSS) is commonly offered, but recurrence risk varies by surgical approach and histological subtype,...
Apoptotic Induction by 1,5-Diaryl-1,4-pentadien-3-one Derivatives in the HL60 Cell Line: In Vitro and In Silico Expression [0.03%]
1,5-二芳基-1,4-戊-3-酮衍生物诱导HL-60细胞系凋亡的体内和体外研究
Arshee Rehman,Zia Udin,Yasar Shah et al.
Arshee Rehman et al.
Background/aim: Despite advancements in therapeutic agents, cancer treatment, especially for leukemia, is still a formidable challenge for the clinician. The promyelocytic leukemia cell line, HL-60, is widely used for the...
Potential of Inflammatory and Nutritional Markers and Clinicopathological Factors for Prognostic Prediction in Osteosarcoma [0.03%]
骨肉瘤预后预测的炎症和营养标志物及临床病理因素的潜在作用
Kazuhiko Hashimoto,Shuniji Nishimura,Koji Goto
Kazuhiko Hashimoto
Background/aim: Prognostic factors for osteosarcoma remain insufficiently defined. This study evaluated the prognostic significance of the neutrophil-to-lymphocyte ratio (NLR), systemic inflammatory response index (SIRI),...
Evaluation of Quality Metrics for Dose Assessment in Field Overlap Regions of VMAT-Based Craniospinal Axis Irradiation [0.03%]
容积旋转调强技术全中枢放疗区域重叠区剂量评估的质量指数评价研究
Christian Ziemann,Florian Cremers,Lisa Muendlein et al.
Christian Ziemann et al.
Background/aim: Patients with meningeosis carcinomatosa or primary brain tumors may require craniospinal irradiation. In craniospinal volumetric modulated arc therapy (VMAT-CSI), field junctions are sensitive regions pron...
PRDX4 Potentially Serves as an Independent Marker for Early Recurrence of Oral Squamous Cell Carcinoma [0.03%]
PRDX4有可能作为口腔鳞状细胞癌早期复发的独立标记物
Taijiro Hashimoto,Takeru Oyama,Yangxian Zhang et al.
Taijiro Hashimoto et al.
Background/aim: Oral squamous cell carcinoma (OSCC), a main histological subtype of oral cavity cancer, remains one of the most prevailing tumors worldwide with the increasing incidence and mortality. Since a high rate of...
A Reminder App for Optimizing Bladder Filling During Radiotherapy for Prostate Cancer: A Pre-study in Healthy Volunteers [0.03%]
一种优化前列腺癌放射治疗期间膀胱充盈的提醒应用程序：健康志愿者中的预研究
Dirk Rades,Carlos A Narvaez-Wolf,Inga C Zwaan et al.
Dirk Rades et al.
Background/aim: The risk of genitourinary toxicity during radiotherapy for prostate cancer was found to be lower for bladder volumes ≥200 ml. An app that reminds patients daily to drink water might be helpful. Before bei...
Cancer Cachexia Predicts Benefit of Immunotherapy Plus Chemotherapy in EGFR-mutant NSCLC After TKI Resistance [0.03%]
免疫治疗联合化疗针对EGFR突变型晚期非小细胞肺癌酪氨酸激酶抑制剂耐药后 cachexia状态预测疗效
Haruka Nakatani,Hayato Kawachi,Tadaaki Yamada et al.
Haruka Nakatani et al.
Background/aim: Cancer cachexia, characterized by weight loss and systemic inflammation, has been associated with poor prognosis in non-small cell lung cancer (NSCLC). However, its impact on treatment outcomes in tumors w...
Multicenter Study
Anticancer research. 2026 May;46(5):2789-2806. DOI:10.21873/anticanres.18159 2026
Musashi1 Enhances Cell Growth and Increases Chemoresistance in Neuroblastoma [0.03%]
Musashi1增强神经母细胞瘤的细胞增殖并增加其化疗耐药性
Elizabeth D Cochran,Jingbo Qiao,Arti Machchhar et al.
Elizabeth D Cochran et al.
Background/aim: Neuroblastoma remains a major cause of pediatric cancer mortality and although intensive multimodal treatment strategies have improved survival, they have also led to an increased risk of long-term treatme...
Proinsulin Promotes Tumor Development in the PANC-1 Pancreatic Adenocarcinoma Cell Line [0.03%]
プロインスリンがPANC-1膵腺adenocarcinoma細胞株の腫瘍発達を促進すること
Tomonori Tsuyama,Hanchen Dong,Takenari Sato et al.
Tomonori Tsuyama et al.
Background/aim: Epidemiological studies have demonstrated that type 2 diabetes mellitus (T2DM) is a risk factor for pancreatic ductal adenocarcinoma (PDAC); however, the underlying mechanisms remain unclear. Recent studie...