Adenylate Kinase 2 Promotes Tumor Progression in Small-cell Lung Cancer via PI3K/AKT/mTOR Signaling [0.03%]
腺苷酸激酶2通过PI3K / AKT / mTOR信号促进小细胞肺癌的发展
Hong-Beum Kim,Yong Sub Na,Seong-Hun Kim et al.
Hong-Beum Kim et al.
Background/aim: Small-cell lung cancer (SCLC) is an aggressive malignancy with limited therapeutic progress. Adenylate kinase 2 (AK2), a mitochondrial isoenzyme involved in nucleotide metabolism and apoptosis regulation, ...
A Prospective Study of Olanzapine and Aprepitant for CINV in Cisplatin-HAIC for Hepatocellular Carcinoma (PROACT) [0.03%]
奥氮平和阿普瑞坦治疗肝细胞癌顺铂HAIC引起的CINV的前瞻性研究( PROACT )
Shunsuke Okuyama,Masayuki Ueno,Takahiro Oi et al.
Shunsuke Okuyama et al.
Background/aim: This study investigated the efficacy and safety of olanzapine and aprepitant in preventing chemotherapy-induced nausea and vomiting in patients with hepatocellular carcinoma (HCC) undergoing cisplatin-base...
Clinical Predictors of Neoadjuvant Chemotherapy Efficacy in Esophageal Squamous Cell Carcinoma [0.03%]
食管鳞癌新辅助化疗疗效的临床预测因素分析
Nobufumi Sekino,Kentaro Murakami,Takeshi Toyozumi et al.
Nobufumi Sekino et al.
Background/aim: Esophageal squamous cell carcinoma (ESCC) is resistant to multidisciplinary treatments. Neoadjuvant chemotherapy (NAC) enhances outcomes but varies in effectiveness, highlighting the need for predictive ma...
Near-infrared Photoimmunotherapy Targeting High-risk Human Neuroblastoma Cells Expressing GD2 [0.03%]
近红外光免疫疗法靶向GD2阳性的高危人神经母细胞瘤细胞
Hiroshi Nouso,Hiroshi Tazawa,Terutaka Tanimoto et al.
Hiroshi Nouso et al.
Background/aim: Neuroblastoma (NB) is a primary malignant tumor of the peripheral sympathetic nervous system in infancy. Despite advances in treatment, the prognosis remains poor for high-risk NB patients. Although immuno...
Clinical-Genomic Risk Discordance in Early HR+/HER2- Breast Cancer: A Real-World Cohort from Japan Demonstrates Treatment Impact of Oncotype DX [0.03%]
早期HR+/HER2-乳腺癌的临床-基因组风险不一致：来自日本的真实世界队列显示Oncotype DX对治疗的影响
Saeko Henmi,Shinichiro Kashiwagi,Hanae Matsuda et al.
Saeko Henmi et al.
Background/aim: The Oncotype DX Recurrence Score (RS) is widely implemented to guide adjuvant chemotherapy in early hormone receptor-positive (HR+)/HER2- breast cancer. However, discordance between RS and conventional cli...
Preserved Adrenal Function After Left Renal Cell Carcinoma With Tumor Thrombus Resection and Right Adrenal Vein Ligation: A Case Report [0.03%]
左侧肾细胞癌伴瘤栓切除联合右侧肾上腺静脉结扎术后保留肾上腺功能一例报告
Dhruv N Desai,Angel Alvarez,Javier González et al.
Dhruv N Desai et al.
Background/aim: Adrenal insufficiency is a recognized complication following adrenalectomy and, less commonly, nephrectomy due to the anatomical and functional relationship between the adrenal glands and kidneys. While un...
Short-term Outcomes of Robotic-assisted Versus Laparoscopic Right Hemicolectomy for Right-sided Colon Cancer: A Retrospective Study [0.03%]
机器人辅助与腹腔镜右半结肠切除术治疗右侧结直肠癌近期疗效的回顾性研究
Satoshi Narihiro,Daichi Kitaguchi,Shunjin Ryu et al.
Satoshi Narihiro et al.
Background/aim: Limited evidence exists regarding the superiority of robotic surgeries (RS) over laparoscopic surgeries (LS) in right hemicolectomy (RHC) for right-sided colon cancer. This study aimed to clarify the safet...
Comparative Study
Anticancer research. 2026 Jan;46(1):493-501. DOI:10.21873/anticanres.17963 2026
Inter-fractional Variation of Linear Energy Transfer Profiles During Carbon-ion Radiotherapy for Pancreatic Cancer [0.03%]
胰腺癌碳离子治疗过程中线性传能谱的逐日差异分析
Yukihiko Yoshimatsu,Takahiro Oike,Makoto Sakai et al.
Yukihiko Yoshimatsu et al.
Background/aim: In carbon-ion radiotherapy (CIRT), a low dose-averaged linear energy transfer (LETd) within the tumor has been suggested as a potential unfavorable prognostic factor for local recurrence. However, inter-fr...
P53-Armed Oncolytic Virotherapy Promotes the Efficacy of PD1 Blockade in Murine Osteosarcoma Tumors [0.03%]
携带P53的溶瘤病毒疗法可增强小鼠骨肉瘤肿瘤PD1阻断的疗效
Miho Kure,Hiroshi Tazawa,Koji Demiya et al.
Miho Kure et al.
Background/aim: Osteosarcoma (OS) is refractory to immune checkpoint inhibitors targeting programmed cell death 1 (PD1)/PD ligand 1 (PD-L1) due to poor immune response. We previously developed telomerase-specific, replica...
Estimation of Tumor Control Probability of Carbon Ion Radiotherapy Using Cancer Type-specific Sensitivity Data [0.03%]
基于癌种特异性敏感性数据的碳离子放疗肿瘤控制概率估算
Eunhye Yu,Takahiro Oike,Makoto Sakai et al.
Eunhye Yu et al.
Background/aim: This study aimed to evaluate whether the predictive performance of tumor control probability (TCP) by carbon ion radiotherapy (CIRT) could be improved by incorporating cancer type-specific carbon ion sensi...