Multi-drug resistance and diversity of mobile genetic elements in Escherichia coli isolated from migratory bird in Poyang Lake [0.03%]
鄱阳湖迁徙鸟类分离的肠杆菌的多重耐药性及可移动遗传元件多样性研究
Haixin Deng,Huiping Liang,Qinghua Zeng et al.
Haixin Deng et al.
With the spread of antibiotic resistance genes such as blaCTX-M-2, dfrA1 and blaNDM-1, the problem of drug resistance in E. coli is becoming increasingly serious[1]. This study aimed to identify integrons genes and MGEs in E. coli isolated ...
Transcriptional evaluation of functional genes of resistance, biofilm and quorum sensing in CTX-M15 ESBL-producing Klebsiella pneumoniae after meropenem concentration based on serum level [0.03%]
基于血清水平的美罗培南浓度对产CTX-M15超广谱β内酰胺酶 Klebsiella pneumoniae 耐药、生物被膜和群体感应功能基因转录的影响研究
Suzana Carstensen,Paula Hansen Suss,Gabriel Burato Ortis et al.
Suzana Carstensen et al.
Background: Klebsiella pneumoniae is a leading cause of multidrug-resistant hospital-acquired infections. Resistance to carbapenems, particularly meropenem, is increasingly reported and often linked to β-lactamase produc...
Emerging concept of genomic islands in bacterial adaptation and pathogenicity [0.03%]
基因组岛屿在细菌适应性和致病性中的新概念
Ingita Dey Munshi,Anshu Mathuria,Harshita Sharma et al.
Ingita Dey Munshi et al.
Genomic Islands (GEIs) are distinct DNA segments acquired through horizontal gene transfer (HGT), driving bacterial evolution and adaptation. These include Pathogenicity Islands (PAIs), Symbiosis Islands, Antibiotic Resistance Islands, Xeno...
Tarek Msadek
Tarek Msadek
Highly Specific Virus-Host Linkages in Mesothermophilic and Circumneutral Hot Springs Microbial Communities [0.03%]
中性热液微生物群落中的病毒与宿主的特异性联结关系
Oscar Salgado,Oscar Martínez,Yessica Rivas et al.
Oscar Salgado et al.
Microbial communities in hot springs are distributed globally and have been extensively characterized regarding their diversity and composition. However, most studies have focused on cellular microbes, with relatively few addressing viruses...
Effect of Pseudomonas aeruginosa ExoU on Airway Epithelial Cells through MUC1-C Nuclear Translocation [0.03%]
铜绿假单胞菌ExoU通过MUC1-C核转位影响气道上皮细胞的作用机制研究
Alexandre Costa Monteiro,Lhousseine Touqui,Alessandra Mattos Saliba
Alexandre Costa Monteiro
The opportunistic pathogen Pseudomonas aeruginosa plays a significant role in hospital-acquired pneumonia, with the secretion of ExoU - a virulence factor expressed by select P. aeruginosa strains - linked to poor clinical outcomes. This is...
Switching off the yeast-to-hyphae transition in Yarrowia lipolytica through histone deacetylase inhibitors [0.03%]
组蛋白去乙酰化酶抑制剂可使解脂耶氏酵母从芽殖到丝状生长的转变过程失活
Martha Viviana Roa-Cordero,Christian Alfonso Arenas-Sepúlveda,María Cristina Herrera-Plata et al.
Martha Viviana Roa-Cordero et al.
Fungi can develop a variety of morphotypes to survive, colonize, adapt and prevail under different environmental conditions. In general, two morphological shapes encompass the others: yeast (unicellular) and hyphae (multicellular). Under sp...
Antimicrobial Resistance in Coagulase Negative Staphylococci: Genome Analysis and Role of Horizontal Gene Transfer [0.03%]
表皮葡萄球菌耐药的基因组分析及水平基因转移的作用
Tansu Dündar,Fatma Köksal Çakirlar
Tansu Dündar
Coagulase-negative staphylococci (CNS) are emerging as significant contributors to antimicrobial resistance, yet their genomic characteristics remain incompletely understood. This study presents a whole-genome analysis of 12 multidrug-resis...
Transposition of transposable element IS1 in Edwardsiella piscicida mutant generated by CRISPR/Cas9 along with λ-Red recombineering system [0.03%]
CRISPR/Cas9及λ-Red重组系统联用构建肠炎沙海菌突变株并发现可移动元件IS1转座事件
Eun Gyeong Lee,Ki Hong Kim
Eun Gyeong Lee
This study aimed to investigate unintended mutations introduced by the CRISPR/Cas9 genome editing system in Edwardsiella piscicida. Whole-genome sequencing was conducted on the wild-type E. piscicida NH1 and its alanine racemase knockout mu...
MibR and LibR are involved in the transcriptional regulation of the ipdC gene in Azospirillum brasilense Sp7 [0.03%]
MibR和LibR参与了Azospirillum brasilense Sp7中ipdC基因的转录调控
Sandra R Reyes-Carmona,Saúl Jijón Moreno,Alberto Ramírez-Mata et al.
Sandra R Reyes-Carmona et al.
Azospirillum brasilense is a PGPR that produces the phytohormone IAA, a signaling molecule involved in bacteria-plant interaction processes. IAA biosynthesis in Azospirillum is mainly carried out via the IPyA pathway in which the enzyme phe...