[Suboptimal care and severe bacterial infection in the French Caribbean area] [0.03%]
法属西印度群岛地区次优治疗与严重细菌感染的关系
E Goisque,E Launay,B Vrignaud et al.
E Goisque et al.
Objective: To study the frequency and types of suboptimal care in initial management of children suffering from a severe bacterial infection (SBI), in a French region where little is known about pediatric SBI epidemiology...
R Cohen,H Haas,M Lorrot et al.
R Cohen et al.
ENT infections are the most common childhood infections and the leading causes of antibiotic prescriptions. These infections are mainly due to viruses and most of them (even if bacterial species are implicated) resolve spontaneously. Theref...
Antibiotic pharmacokinetic and pharmacodynamic parameters in pediatric clinical practice [0.03%]
儿科临床实践中的抗菌药药物动力学和药物效用学参数
R Cohen,E Grimprel
R Cohen
Progress in the knowledge of antibiotic mechanisms of action allows to determine the pharmacodynamics/pharmacokinetic (PK/PD) parameters predictive of antibiotic efficacy in bacterial infections. According to the antibiotic compound, the ba...
R Cohen,L de Pontual,Y Gillet et al.
R Cohen et al.
This section summarizes the empirical antimicrobial treatment according to the less frequent bacterial species responsible for infection whether community-acquired or nosocomial. It specifies their role in diseases and the recommended antib...
H Haas,E Launay,P Minodier et al.
H Haas et al.
Surgical site infections are the leading cause of perioperative morbidity and mortality as well as increased costs following surgery. Among preventive measures, antibiotic prophylaxis, when indicated, significantly decreases these risks. Ad...
R Cohen,J Raymond,L Hees et al.
R Cohen et al.
The implementation of pneumococal conjugate vaccines (PCVs) 7 then 13 valent (Prevenar13®) in 2010-2011 has significantly changed the profile of pneumococcal meningitis. Since 3 years, the National Pediatric Meningitis Network of the Pedia...
Antibiotic therapy of bone and joint infections in children: proposals of the French Pediatric Infectious Disease Group [0.03%]
法国儿科传染病组关于儿童骨和关节感染抗菌治疗的建议
M Lorrot,Y Gillet,C Gras Le Guen et al.
M Lorrot et al.
Acute hematogenous bone and joint infections (osteomyelitis, septic arthritis, osteoarthritis, and spondylodiscitis) affect more frequently children younger than 5 years of age. Early diagnosis and prompt treatment are needed to limit the r...
Y Gillet,M Lorrot,R Cohena et al.
Y Gillet et al.
Bacterial skin and soft tissues infections are common in children and frequently do not require systemic antibiotics, especially if lesions are superficial. Careful washing is always indicated in superficial lesions and is often sufficient....
R Cohen,J Raymond,D Gendrel
R Cohen
Acute gastroenteritis (AGE) are usually caused by viruses, especially Rotavirus and Norovirus. Among the bacterial causes, very few warrant antibiotic treatment, mainly Shigella, Vibrio cholerae, Campylobacter (only for severe cases, partic...
R Cohen,J Raymond,E Launay et al.
R Cohen et al.
Urinary tract infections are the most frequent documented bacterial infections in children. The antibiotic choices proposed in this manuscript are based on the guidelines published by the Pediatric Infectious Disease Group (GPIP) and the Fr...