Provocation test on stairs: a new accessible method to cholinergic urticaria diagnosis [0.03%]
阶梯式激发试验:一种新的胆碱能性荨麻疹诊断方法
G Azizi,S Dortas Jr,A França et al.
G Azizi et al.
Background. Cholinergic urticaria (CholU) is characterized by itching and/or stinging, painful micro wheals due to systemic heating. There are two standardized protocols to diagnose CholU using an exercise bike with heart rate or warming pa...
The association between baseline IgE level and urticaria control at six months of omalizumab treatment in chronic urticaria [0.03%]
基线IgE水平与omalizumab治疗6个月慢性自发性荨麻疹控制之间的关系
G Tuncay,E Damadoglu,G Karakaya et al.
G Tuncay et al.
Background. There is limited data on the use of baseline IgE level as a predictor of omalizumab response in chronic urticaria (CU). The aim of the present study was to determine if baseline serum total IgE level is associated with response ...
Is gastrointestinal epithelial barrier dysfunction the only responsible for sensitization to food allergens? [0.03%]
肠道上皮屏障功能障碍是食物过敏原致敏的唯一原因吗?
R Asero,V Pravettoni,D Villalta et al.
R Asero et al.
Epithelial barriers are crucial defenses against pathogens and allergens, and recent theories suggest that environmental factors may compromise them, leading to type 2 inflammation and conditions such as asthma, atopic dermatitis, food alle...
P Simão Coelho,G Martins-Dos-Santos,M Mikovic et al.
P Simão Coelho et al.
Background. Childhood asthma, a chronic inflammatory disease, is linked to sleep-breathing disorders (SBD). The vulnerability of asthmatic children to SBDs is well-established, yet limited research focuses on adolescents. This study address...
The added value of targeting airway hyperresponsiveness by blocking TSLP in the management of severe asthma [0.03%]
针对重度哮喘管理中通过阻断TSLP靶向气道高反应性的附加价值
A Vaghi,M B Bilò,F Bini et al.
A Vaghi et al.
Airways hyperresponsiveness (AHR) is a pathognomonic event of asthma in which the airways are reactive to various bronchoconstrictor stimuli at 'doses' that normally have no bronchoconstrictor effect in non-asthmatics. AHR is an objective m...
Severe chronic spontaneous urticaria responding and not responding to omalizumab: analysis of the prognostic value of known and novel in-vitro variables [0.03%]
奥马珠单抗治疗反应性和非反应性重度慢性自发性荨麻疹的分析及预后价值:已知和新型体外变量研究
R Asero,P Calzari,S Ferrucci et al.
R Asero et al.
Background. Chronic spontaneous urticaria (CSU) response to anti-IgE treatment can be rapid, late or absent. Recently, potential mechanisms of activation of mast cells alternative to FceRI, including mas-related G protein-coupled receptor X...
Cannabis sativa as a clinically relevant nsLTP allergen in the Mediterranean region: a case series exemplifying different possible routes of sensitization [0.03%]
大麻作为一种具有临床意义的nsLTP过敏原在地中海地区的作用:不同过敏途径实例研究系列
A Bennici,D Grixti Soler,G Marcassa et al.
A Bennici et al.
Cannabis is the most widely used drug worldwide sought for recreational and medicinal purposes. Cannabis allergy was first described 50 years ago but has become more frequently reported over the past decade due to a larger industrial and do...
Assessment of concentrations of multidirectional omega-3 fatty acids in inborn errors of immunity with predominantly antibody defects: a pilot study [0.03%]
面向以抗体缺陷为主的先天性免疫缺陷病患者开展多元omega-3脂肪酸浓度评估的试点研究
K Napiórkowska-Baran,B Szymczak,J Lubański et al.
K Napiórkowska-Baran et al.
Background.Omega-3 fatty acids are involved in many processes in the human body. Their beneficial effects were documented mainly in relation to cardiovascular and immune systems. Patients with immunodeficiencies with predominantly antibody ...
A narrative review on allergy and exposure to domestic and non-domestic animals: favorable and unfavorable effects [0.03%]
关于接触家养及非家养动物与过敏:有利和不利影响的叙述性综述
G Liccardi,M Martini,M B Bilò et al.
G Liccardi et al.
The aim of this contribution was to highlight the "favorable" and "unfavorable" roles of domestic and non-domestic animals on airway sensitization processes and on the type/severity of the clinical symptoms induced by their exposure. We per...
Efficacy and tolerability of house dust mites subcutaneous immunotherapy with monomeric allergoid: an Italian multicenter study [0.03%]
意大利多中心研究评估粉尘螨单体变应原免疫治疗的疗效和耐受性
E Compalati,I Atzeni,S Cabras et al.
E Compalati et al.
Background. Subcutaneous immunotherapy is an effective treatment of respiratory allergy and allergoids offer a treatment option characterized by reduced IgE-binding properties to improve the safety profile. Purpose of this study was to inve...