Comparison of the characteristics of patients with chronic urticaria receiving standard- or high-dose omalizumab [0.03%]
omalizumab标准剂量与高剂量治疗慢性自发性荨麻疹患者的临床特征比较分析
G Tuncay,E Damadoglu,G Karakaya et al.
G Tuncay et al.
Background. In patients whose chronic urticaria (CU) cannot be controlled with omalizumab 300 mg and antihistamines, the dose can be increased up to 600 mg. The study aimed to compare the clinical characteristics of patients receiving 300 m...
Early markers of baked milk and egg tolerance in young children with IgE-mediated immediate reactions [0.03%]
IgE介导的即刻反应型幼童体内烘焙奶和鸡蛋容耐受性的早期标示物
M Y Altunbas,E Y Gungoren,S Can et al.
M Y Altunbas et al.
Background. Children with milk and egg allergies have outcomes in which, three-quarters are tolerant to baked forms of the allergenic food. Identifying predictors of tolerance to baked foods for IgE-mediated immediate-type reactions may gui...
Rhinitis or asthma among adults as associated factors with symptoms of depression [0.03%]
成人过敏性鼻炎或哮喘与抑郁症状的相关性分析
T I Bedolla-Pulido,J Morales-Romero,N A Pulido-Guillén et al.
T I Bedolla-Pulido et al.
Background. It has been observed that diseases such as rhinitis and asthma not only affect the physical health of individuals but can also significantly impact their psychological well-being. The aim of this study is to analyze the relation...
Provocation test on stairs: a new accessible method to cholinergic urticaria diagnosis [0.03%]
阶梯式激发试验：一种新的胆碱能性荨麻疹诊断方法
G Azizi,S Dortas Jr,A França et al.
G Azizi et al.
Background. Cholinergic urticaria (CholU) is characterized by itching and/or stinging, painful micro wheals due to systemic heating. There are two standardized protocols to diagnose CholU using an exercise bike with heart rate or warming pa...
The association between baseline IgE level and urticaria control at six months of omalizumab treatment in chronic urticaria [0.03%]
基线IgE水平与omalizumab治疗6个月慢性自发性荨麻疹控制之间的关系
G Tuncay,E Damadoglu,G Karakaya et al.
G Tuncay et al.
Background. There is limited data on the use of baseline IgE level as a predictor of omalizumab response in chronic urticaria (CU). The aim of the present study was to determine if baseline serum total IgE level is associated with response ...
Is gastrointestinal epithelial barrier dysfunction the only responsible for sensitization to food allergens? [0.03%]
肠道上皮屏障功能障碍是食物过敏原致敏的唯一原因吗？
R Asero,V Pravettoni,D Villalta et al.
R Asero et al.
Epithelial barriers are crucial defenses against pathogens and allergens, and recent theories suggest that environmental factors may compromise them, leading to type 2 inflammation and conditions such as asthma, atopic dermatitis, food alle...
P Simão Coelho,G Martins-Dos-Santos,M Mikovic et al.
P Simão Coelho et al.
Background. Childhood asthma, a chronic inflammatory disease, is linked to sleep-breathing disorders (SBD). The vulnerability of asthmatic children to SBDs is well-established, yet limited research focuses on adolescents. This study address...
The added value of targeting airway hyperresponsiveness by blocking TSLP in the management of severe asthma [0.03%]
针对重度哮喘管理中通过阻断TSLP靶向气道高反应性的附加价值
A Vaghi,M B Bilò,F Bini et al.
A Vaghi et al.
Airways hyperresponsiveness (AHR) is a pathognomonic event of asthma in which the airways are reactive to various bronchoconstrictor stimuli at 'doses' that normally have no bronchoconstrictor effect in non-asthmatics. AHR is an objective m...
Severe chronic spontaneous urticaria responding and not responding to omalizumab: analysis of the prognostic value of known and novel in-vitro variables [0.03%]
奥马珠单抗治疗反应性和非反应性重度慢性自发性荨麻疹的分析及预后价值：已知和新型体外变量研究
R Asero,P Calzari,S Ferrucci et al.
R Asero et al.
Background. Chronic spontaneous urticaria (CSU) response to anti-IgE treatment can be rapid, late or absent. Recently, potential mechanisms of activation of mast cells alternative to FceRI, including mas-related G protein-coupled receptor X...