A novel high-sensitivity fluorescence detection technology for zearalenone based on the PER-triggered crRNA conformational change and CHA-coordinated energy supply [0.03%]
一种基于PER触发crRNA构象变化和CHA协调能量供应的高灵敏荧光检测技术检测玉米赤霉烯酮
Runlong Ma,Yijing Xiao,Wentong Yu et al.
Runlong Ma et al.
Zearalenone (ZEN), frequently encountered in corn, is a hazardous mycotoxin capable of impairing liver and kidney function, compromising immune responses, and potentially inducing carcinogenesis. Current detection methodologies are hampered...
Engineering a nanobody-alkaline phosphatase bifunctional probe for enhanced immunoassay performance toward microcystin-LR [0.03%]
工程化纳米抗体-碱性磷酸酶双功能探针用于提高微囊藻毒素-LR免疫分析性能
Yingying Ma,Tong Ai,Xinyi Chen et al.
Yingying Ma et al.
Eutrophication caused by excessive nutrient discharge has led to the frequent occurrence of cyanobacterial blooms, during which toxic metabolites such as microcystins (MCs) are released into aquatic environments. Among these, microcystin-LR...
Preparation of MIL-68@Fe3O4@PVDF composites via the spray phase inversion method and their magnetic solid-phase extraction of parabens and bisphenol A [0.03%]
利用喷射相转化法制备MIL-68@Fe3O4@PVDF复合材料及其固相萃取对羟基苯甲酸酯和双酚A的研究
Xinwen Hu,Yong Zhang,Zhihao Chen et al.
Xinwen Hu et al.
In this study, the spray phase inversion method was employed for the first time to prepare MIL-68@Fe3O4@PVDF. The preparation process involved dispersing Fe3O4 in a PVDF/DMF solution; when the Fe3O4-loaded PVDF solution was atomized and spr...
Capillary-SERS sensor based on aptamer-mediated inhibition of nanozyme catalysis for ultrasensitive detection of homocysteine in serum from hepatocellular carcinoma patients [0.03%]
基于适配体介导的纳米酶催化抑制的毛细管SERS传感器用于检测肝癌患者血清中半胱氨酸的超灵敏检测
Wangxuan Xia,Juncheng Shi,Yongjin Yu et al.
Wangxuan Xia et al.
Early detection and sensitive monitoring of homocysteine (Hcy) in serum are crucial for liver cancer screening. Here, we developed a capillary-based SERS sensor utilizing aptamer capture of Hcy and the highly catalytic properties of nanozym...
A green analytical assay for the quantitation of bioavailable phosphorus in soils: in situ extraction and smartphone-based measurement [0.03%]
一种绿色的分析方法，用于测定土壤中可利用磷含量：现场提取和智能手机测量
Stella Sales Macedo,Edilene Cristina Ferreira,Arnaldo Alves Cardoso
Stella Sales Macedo
Bioavailable phosphate (BAP) is an essential macronutrient for plant biomass formation and agricultural productivity. However, excess phosphate can contribute to the eutrophication of water bodies, exacerbating problems related to water ava...
Synergistic interface engineering of a Co(OH)2@AgNPs heterostructure for trace electrochemical Hg2+ detection [0.03%]
协同界面工程构建Co(OH)_2@AgNPs异质结构用于电化学痕量Hg^{}+检测
Yanchao Sun,Hongliang Dai,Zheng Wang et al.
Yanchao Sun et al.
The on-site detection of toxic mercury ions (Hg2+) at trace levels is critical for environmental monitoring and compliance with stringent environmental regulations. However, developing electrochemical sensors that simultaneously achieve hig...
Study on the detection of prostate cancer using MIRA-CRISPR/Cas12a technology [0.03%]
基于MIRA-CRISPR/Cas12a技术的前列腺癌检测研究
Yuanyuan Chen,Daiyan Tang,Jin Zhan et al.
Yuanyuan Chen et al.
Background: Prostate cancer (PCa) is the most diagnosed cancer among men globally and a leading cause of cancer-related mortality. However, current conventional prostate diagnostic methods fail to meet the growing demands of clinical practi...
Zirconium and vanadium bimetallic organic framework nanozyme for bioenzyme-free colorimetric and photothermal dual-mode direct detection of organophosphorus pesticides [0.03%]
一种用于无酶比色和光热双模式直接检测有机磷农药的锆-钒有机框架纳米酶
Chenxu Wang,Ningjing Du,Zhe You et al.
Chenxu Wang et al.
Presently, the majority of colorimetric methods for the detection of organophosphorus pesticides (OPs) generally require the presence of bioenzymes coupled with just single-signal detection mode. Herein, using VCl3 and ZrCl4 as the metal pr...
Metabolomics-based study of potential biomarkers and metabolic pathways in sepsis-associated acute kidney injury [0.03%]
基于代谢组学的脓毒症相关急性肾损伤潜在生物标志物和代谢通路研究
Xinyi Sun,Fang Li,Gaoyin Yang et al.
Xinyi Sun et al.
One of the most frequent consequences of sepsis is sepsis-associated acute kidney injury (SA-AKI), which increases hospitalization and mortality risk. A qualitative and quantitative analysis of the metabolic components in SA-AKI patients ve...
Ratiometric fluorescence determination of Gd(III) using plumbagin: method validation and analysis of real samples [0.03%]
苦蔥紅素比率熒光法测定钆(III): 方法验证及实际样品分析
Do Tam Nhan,Le Thi Thanh Tran,Nguyen Le Anh et al.
Do Tam Nhan et al.
In this study, the spectroscopic interaction between plumbagin (PLB) and Gd(III) was studied using UV-vis and fluorescence spectroscopy techniques. When Gd(III) coordinated with PLB, clear spectral changes were found, together with the appe...