Analytical strategies for multi-omics profiling of exercise-induced muscle damage and recovery: from sampling and separations to chemometric biomarker discovery [0.03%]
用于运动诱导的肌肉损伤和恢复的多组学谱分析策略：从采样及分离到化学计量生物标志物发现
Le Xu,Yongrui Tang,Liufeng Shi et al.
Le Xu et al.
Exercise-induced muscle damage (EIMD) triggers a coordinated cascade of molecular responses that drive tissue repair and physiological adaptation. Recent advances in analytical chemistry have enabled multi-omics profiling to capture these c...
An ion chromatographic method for the purity analysis of the poorly soluble energetic coordination compound lead NTOate [0.03%]
一种用于分析难溶性推进剂配合物NTO铅盐纯度的离子色谱方法研究
Fengyi Xia,Jiexin He,Dongxu Zhang et al.
Fengyi Xia et al.
An ion chromatography (IC) method was developed for the purity determination of the poorly soluble energetic coordination compound lead NTOate (lead(II) salt of 3-nitro-1,2,4-triazol-5-one). To overcome the limitations of conventional ethyl...
Development and validation of a QbD-integrated sensitive RP-HPLC method for quantitation of fenofibrate: an application in quality control [0.03%]
一种QbD指导下的定量环糊精包合的非诺贝特的RP-HPLC法及其验证：用于质控分析
Romi Singh,Abhiram Kumar,Ashutosh Pareek et al.
Romi Singh et al.
Aim: The present study aims to develop and validate a robust, sensitive HPLC method for the estimation of fenofibrate in a gel-matrix sustained-release tablet formulation designed to prevent alcohol-induced dose dumping. ...
Unsupervised and supervised methodologies for identification of sample pixels in Fourier transform infrared microspectroscopic images [0.03%]
傅立叶变换红外显微光谱图像样本像素识别的无监督和有监督方法学研究
Xiangyu Zhao,Yudong Tian,Jingzhu Shao et al.
Xiangyu Zhao et al.
Mid-infrared spectroscopy is a promising label-free technique that can offer insights into morphological and pathological alterations in biological tissues at the molecular level. Owing to the development of the Fourier Transform InfraRed (...
Rapid detection of psychoactive and new psychoactive substances using qualitative color tests: chemistry, techniques, and applications [0.03%]
用于精神活性物质和新型精神活性物质快速定性检测的颜色测定法：化学、技术和应用
Fabio Antonio Cajamarca Suquila,Andrés Fernando Lancheros Sánchez,Julie Gesselle Benavides Melo
Fabio Antonio Cajamarca Suquila
This review may serve as a guide to develop technical and analytical guidelines for the selection and application of color test screening protocols for the detection of psychoactive substances (PSs), including new psychoactive substances (N...
Unveiling the geographical signature of black tea through UHPLC-quadrupole-Orbitrap Exploris HRMS analysis [0.03%]
基于UHPLC-q Orbitrap Exploris高分辨质谱的茶叶产地鉴别研究
Subodh Kumar Budakoti,Khalid Anwar,Nagendla Narendra Kumar et al.
Subodh Kumar Budakoti et al.
Understanding the geographical differentiation of black tea is essential for exploring the influence of territory on its chemical composition. In this study, black tea (powder) samples from key tea-producing regions, including Siliguri, Ass...
Construction of a mito-targeting fluorescent probe for specific identification of Al3+ in environmental and biological systems [0.03%]
用于环境及生物体系中Al³⁺可视化检测的线粒体定位型荧光探针的构建
Guiying Hu,Aoshanshan Fan,Yanfei Qin et al.
Guiying Hu et al.
A novel benzothiazole-based fluorescent probe HMH-Al was designed and synthesized for the selective sensing of Al3+. It showed a remarkable turn-on fluorescence response toward Al3+ with bright cyan-blue emission in EtOH/H2O (v/v = 3 : 2). ...
Self-amplifying cascade-triggered Au NP assembly strategy for ultrasensitive cTnI detection with dynamic light scattering [0.03%]
基于自放大型级联触发的Au纳米颗粒组装策略实现超灵敏心肌肌钙蛋白I动态光散射检测
Chen Chen,Yingqing Li,Xiaosong Yang et al.
Chen Chen et al.
Here, we report an ultrasensitive dynamic light scattering (DLS) immunosensor for cardiac troponin I (cTnI) that leverages a novel self-cascading reaction synergistic amplification strategy by using metal organic framework (MOF) materials. ...
Integration of a screening-guided near-infrared aptasensor into a portable platform for quantitative on-site detection of N1-methyladenosine [0.03%]
一种用于现场定量检测N1-甲基腺苷的便携式近红外适配子传感器的研发
Qi Pang,Dandan Zhang,Ruilin Ma et al.
Qi Pang et al.
N1-Methyladenosine (m1A) is an important RNA modification associated with diverse biological processes and disease states, yet rapid and quantitative on-site detection of m1A remains challenging. Herein, we report a near-infrared aptasensor...
A ratiometric fluorescence/colorimetric dual-response sensor based on fluorescent nanozymes and smartphone-assisted readout for the accurate determination of glyphosate residues [0.03%]
一种基于荧光纳米酶和智能手机辅助读出的比值型荧光/比色双响应传感器，用于准确测定草甘膦残留量
Xuhai Ding,Ying Zhang,Tao Bo et al.
Xuhai Ding et al.
In this study, a ratiometric fluorescence/colorimetric sensor using copper-based metal-organic framework nanozymes (Cu-BH) was developed for the detection of glyphosate (Gly). The sensor utilized the intrinsic fluorescence properties of the...