Development and validation of a cross-species breath metabolomics platform for translational VOC analysis [0.03%]
一种跨物种呼吸代谢组平台的开发与验证用于转化性VOC分析
Zhiheng Yu,Yongyan Ji,Zijun Meng et al.
Zhiheng Yu et al.
The lack of universal cross-species sampling and quality control methods has limited the potential of breath metabolomics to advance from clinical discovery to mechanistic validation. To address this challenge, this study developed and syst...
A new strategy for improving the precision and accuracy of isotope ratio analysis by quadrupole ICP-MS with the optimization of ion beam trajectory [0.03%]
一种优化离子束轨迹以提高四极杆ICP-MS同位素比精确度和准确度的新策略研究
Xing Li,Haitao Li,Dingwen Zhang et al.
Xing Li et al.
Non-traditional stable isotopes are widely utilized in geoscience and other fields. However, it remains challenging to analyze many samples quickly with high accuracy and precision. In this study, new optimization strategies are proposed to...
Digital image method based on a smartphone assisted by hydrophobic natural deep eutectic solvent for iron quantification in dietary supplements [0.03%]
基于疏水性天然深共熔溶剂的智能手机数字图像法用于膳食补充剂中铁的定量检测
Gabriel Bercley de Lima Vitorino,Jackson Rodrigo Dos Santos Silva,Vinícius de Alcântara Carvalho et al.
Gabriel Bercley de Lima Vitorino et al.
Quality control in dietary supplements is necessary to ensure their safety and effectiveness due to their wide consumption. Conventional methods often include the use of toxic solvents, and complex, high power consumption and expensive inst...
A quinoxaline-based conjugated microporous polymer-coating for solid phase microextraction of polycyclic aromatic hydrocarbons in environmental samples [0.03%]
一种用于环境样品中多环芳烃固相微萃取的基于喹噁啉的共轭微孔聚合物涂层
Gang Xiang,Liushi Xu,Zheng Li et al.
Gang Xiang et al.
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants with severe ecological toxicity, released via both biogenic and anthropogenic pathways. Ultra-sensitive analytical methods for the quantitative monitoring of ...
Fluorescence sensor array integrated with machine learning: robust discrimination of multiple metal ions using carboxyl-rich carbon dots [0.03%]
基于机器学习的富羧基碳点荧光传感器阵列：多种金属离子的稳健识别
Yixiang Li,Weidong Zhang,Da Chen et al.
Yixiang Li et al.
Accurate identification and reliable monitoring of metal ions (MIs) are critically important due to their persistent toxicity, bioaccumulation potential, and significant environmental and public health risks, even at trace concentrations. H...
Single-probe cascade determination of multiple analytes by a tandem reaction of copper nanoclusters [0.03%]
单探针串行反应法同时检测多种分析物
Bo Zhao,Huijun Zhang,Liuyang Wang et al.
Bo Zhao et al.
A new type of red-emitting copper nanoclusters (Cu NCs) was synthesized and applied to the sequential detection of multiple analytes. Remarkably, a fluorescent and colorimetric dual-mode response was achieved via a tandem reaction of the Cu...
Rapid identification of chemical constituents of Liaogu formula based on UHPLC-Q-TOF-MSE combined with the UNIFI platform [0.03%]
基于UHPLC-Q-TOF-MSE结合UNIFI平台快速识别辽鼓方化学成分
Xin Li,Caiying Liu,Liqi Ng et al.
Xin Li et al.
Chemical components of Liaogu Formula (LGF) were analysed using ultra performance liquid chromatography-quadrupole-time of flight-mass spectrometry (UHPLC-Q-TOF-MSE) combined with the UNIFI platform. The analysis was conducted using an Infi...
A magnetic separation-based dual-mode aptasensor integrating FRET fluorescence and UV absorption for early diagnosis of hepatocellular carcinoma [0.03%]
一种基于磁性分离的双模式核酸适配子传感器用于肝细胞癌的早期诊断：结合荧光共振能量转移和紫外吸收技术
Jianghua Wang,Jianfeng Tang
Jianghua Wang
Early diagnosis of hepatocellular carcinoma (HCC) is crucial for improving patient survival; however, conventional detection methods using HepG2 cells (a typical HCC cell line) have inherent limitations. To address this issue, we constructe...
Simple yet sensitive MicroRNA detection using allosteric probe-initiated triple amplification and Cas13a/crRNA-based amplification reaction [0.03%]
一种使用别构探针和Cas13a/crRNA体系的三重级联信号放大的简单且灵敏的MicroRNA检测方法
He Chen,Chaonan Zhang
He Chen
MicroRNAs (miRNAs) have emerged as promising biomarkers for early diagnosis and management of degenerative disc disease (DDD); however, their low abundance and high sequence homology pose significant challenges for clinical detection. Herei...
SERS-based detection of pesticide residues in food: substrate fabrication, optimization, and applications [0.03%]
基于SERS的食物中农药残留检测：基质制备、优化及应用研究
Yuhang Que,Ling Xin,Lingyao Zhu et al.
Yuhang Que et al.
Surface-enhanced Raman scattering (SERS) technology, with its molecular fingerprint recognition, high sensitivity, rapid detection, and non-destructive analysis, has become a key research direction in the detection of pesticide residues in ...