An advanced GC method for comprehensive residual solvent analysis: overcoming co-elution with orthogonal columns and quantification by mass spectrometry [0.03%]
一种先进的气相色谱法全面分析残留溶剂：利用正交柱克服共洗脱并用质谱法定量
Ruba Arulraj,Vinay Vishwanath,Sharad Duche et al.
Ruba Arulraj et al.
A robust and comprehensive gas chromatographic method was developed to identify and quantify the 57 residual solvents listed in the ICH guidelines, all in a single, 30-minute chromatogram. The proposed approach, featuring dual orthogonal co...
Environmentally friendly electrochemical and spectrophotometric strategies for sensitive determination of nintedanib in complex matrices [0.03%]
复杂基质中奈达铂恩环境友好型电化学和分光光度法的敏感测定
Özgür Üstündağ,Marwah Naser,Wiem Bouali et al.
Özgür Üstündağ et al.
Precise quantification of nintedanib (NIN) is essential due to its widespread clinical use and the need for reliable quality control in pharmaceutical and biological samples. In this study, a sensitive electrochemical sensor based on a mult...
Quantitative determination of maslinic acid and oleanolic acid in olive pomace using high-speed shear extraction and liquid chromatography [0.03%]
采用高速剪切提取和液相色谱法定量测定橄榄渣中 Maslinic Acid 和 Oleanolic Acid 的含量
Sheng-Bing Wang,Kun Yang,Dong Pei et al.
Sheng-Bing Wang et al.
Olive pomace contains abundant maslinic acid and oleanolic acid, which are pentacyclic triterpenoid compounds with excellent biological activity. In this study, a method combining high-speed shear extraction and HPLC analysis was developed ...
Construction of a highly sensitive electrochemical sensing platform using an Au-RGO-MWCNTs nanocomposite for the synergistic amplification of rutin detection [0.03%]
一种用于 synergistic放大rutin检测的Au-RGO-MWCNTs纳米复合材料的高灵敏型电化学传感器的构建
Ling-Zhi He,Xiang Li,Zhi-Wen Zeng et al.
Ling-Zhi He et al.
Rutin, a naturally occurring bioactive flavonoid glycoside, has considerable medicinal importance, making its accurate and rapid detection of great significance. Herein, we report a highly sensitive electrochemical sensor for the determinat...
A dual mode turn-on probe for H2O2 sensing via fluorescence and colorimetry in live cells and serum [0.03%]
一种双模式荧光和比色传感过氧化氢的探针
Weitian Chen,Hui Dong,Siyu Wang et al.
Weitian Chen et al.
Hydrogen peroxide (H2O2), as a crucial intracellular reactive oxygen species (ROS) and secondary messenger, plays a key role in various physiological and pathological processes. Therefore, accurate detection of H2O2 is of great significance...
Selection and characterization of DNA aptamers specific to trichlorfon [0.03%]
特异识别杀虫剂三氯苯酚的DNA适配体的筛选与表征
Shuting Yang,Dan Wei,Ziyu He et al.
Shuting Yang et al.
In this study, six candidate DNA aptamers specific to trichlorfon were successfully obtained through 16 rounds of capture-SELEX. Their binding affinities were rigorously evaluated and comparatively analyzed using three orthogonal techniques...
Phosphate-mediated fluorescence switching in a UiO-66-NH2/red carbon dot hybrid for ratiometric and smartphone-assisted visual detection of ethephon [0.03%]
基于磷酸盐调节的UiO-66-NH2/红色碳点杂化材料荧光切换比率型和智能型检测乙烯利痕迹研究
Xiao Hu,Rui Pan,Shufei Huang et al.
Xiao Hu et al.
A smartphone-integrated ratiometric fluorescent platform was developed for on-site quantitative and visual detection of ethephon (ETH) using a UiO-66-NH2/red carbon dots (R-CD) hybrid probe. The R-CDs were synthesized from green tea via an ...
DNAzyme-aptamer electrochemical biosensor for Pb(II) and Hg(II) determination: robust validation in food matrices and water samples [0.03%]
一种用于食品和水样品中铅和汞测定的DNA酶电化学生物传感器及其稳健验证方法
Chang Su
Chang Su
A dual-recognition electrochemical biosensing platform was developed for the sensitive and selective determination of trace Pb(II) and Hg(II) in food and water matrices. The design integrates a Pb(II)-responsive DNAzyme and an Hg(II)-respon...
Analytical workflows in salivary metabolomics for athlete stress monitoring: sampling, platform selection, and translation challenges [0.03%]
用于运动员压力监测的唾液代谢组学分析 workflow：采样、平台选择和转化挑战
Fei Liu,Xiaotian Gao,Xiaoping Wang et al.
Fei Liu et al.
Salivary metabolomics is increasingly positioned as a low-burden biochemical layer for athlete monitoring, but its translational value depends less on biomarker novelty alone than on whether the analytical workflow is sufficiently standardi...
A novel peroxidase-mimicking Cu,S co-doped carbon dot nanozyme for dual-mode lactate biosensing in serum and sweat [0.03%]
一种新型的模拟过氧化物酶的Cu,S共掺杂碳点纳米酶双模式乳酸生物传感器用于血清和汗液中检测
Ali M Alaseem,Glowi Alasiri,Razan Orfali et al.
Ali M Alaseem et al.
Lactate monitoring is of considerable importance because it serves as a key indicator of metabolic status and tissue oxygen deficiency. Its concentration is widely used to evaluate disease severity in clinical diagnosis as well as physical ...