Recombinase polymerase amplification via proximity hybridization-triggered amplification conversion for detecting diverse nucleic acid targets [0.03%]
基于邻位杂交触发扩增转换的重组酶聚合酶扩增技术用于检测多种核酸靶标
Lutan Zhang,Yuxiao Ma,Wenbo Wang et al.
Lutan Zhang et al.
In this study, we present a novel nucleic acid testing paradigm termed "amplification conversion," which decouples target recognition from amplification to create a detection platform adaptable to diverse target types. Unlike conventional t...
A polymer-integrated flexible gold nanotriangle array for quantitative and nondestructive SERS detection of thiram on apples [0.03%]
一种聚合物集成的柔性金纳米三角阵列用于苹果表面噻菌灵的量化及非破坏性SERS检测研究
Ze-Bo Zheng,Xiao-Hui Sun,Wan-Hui Guo et al.
Ze-Bo Zheng et al.
To enable rapid in situ detection of pesticide residues on foods with non-planar surfaces, a polymer-integrated flexible surface-enhanced Raman scattering (SERS) substrate was constructed and demonstrated using apples as a model. An ordered...
Responsive red carbon dots with dual-wavelength emission for anti-counterfeiting [0.03%]
用于防伪的具有双波长发射的红色碳点
Jingjing Chen,Kaiqing Wu,Mengyi Xi et al.
Jingjing Chen et al.
Fluorescence (FL)-based anti-counterfeiting technologies relying on visible color variations are increasingly vulnerable to counterfeiting, posing a critical challenge to security levels. To address this issue, as proof-of-concept research,...
Recovery of TNT from post-blast soil samples: effects of soil type, extraction methodology, and storage conditions [0.03%]
土壤类型、提取方法和储存条件对爆炸后土壤样本中TNT回收的影响研究
A J Hecker,H Upadhyaya,J V Goodpaster
A J Hecker
Traditionally, determination of explosives and their decomposition products in soil samples involves a 24-hour ultrasonic solid-liquid extraction (SLE) using acetonitrile followed by a "salting out" liquid-liquid extraction (LLE). Alternati...
Smart dual-wavelength UV-vis spectroscopic method and smartphone-based RGB method for the rapid quantification of pyronaridine tetraphosphate: integration with the SDG approach [0.03%]
用于快速测定磷酸吡罗阿抗素的智能双波长UV-vis光谱法和基于智能手机的RGB法：与SDG相结合的方法
Jenish H Parekh,Abhishek Munjapara,Bhavesh N Socha et al.
Jenish H Parekh et al.
The proposed study is based on the development of the UV-vis spectrum of pyronaridine tetraphosphate by AI, attention-based recurrent neural networks, DFT and in-lab experiments. This novel smart method was developed using water to maintain...
Research on a highly sensitive aptamer sensor for Vibrio alginolyticus based on CRISPR-Cas13a and T7 transcription cascade amplification [0.03%]
基于CRISPR-Cas13a和T7转录级联扩增的高灵敏度藻凝胶弧菌适配子传感器研究
Yukun Zhao,He Sun,Yue Wan et al.
Yukun Zhao et al.
Vibrio alginolyticus is a prevalent aquatic pathogen that poses significant risks to public health. Thus, the development of rapid and highly sensitive detection methods is imperative. In this study, we developed a novel aptasensor leveragi...
Analytical method development for multiresidue determination in water using automated parallel dispersive pipette extraction and HPLC-DAD [0.03%]
基于自动化并行分散式移液萃取和HPLC-DAD的多残留分析方法的发展
João Pedro Ossucci Martins,Augusto Bortolotto,Francielle Crocetta Turazzi et al.
João Pedro Ossucci Martins et al.
This work presents an automated parallel dispersive pipette extraction (Au-Pa-DPX) technique for analyzing nine organic compounds from different classes in river water. Separation and detection were performed using high performance liquid c...
A nitrogen-doped carbon dot fluorescent probe for sensitive detection of metronidazole in pharmaceutical samples and evaluation of its cytotoxicity and cell imaging performance [0.03%]
一种氮掺杂的碳点荧光探针及其在药物样品中检测甲硝唑中的应用，并评估其细胞毒性及成像性能
Jiahui Li,Jingui Zhong,Hanyan Wei et al.
Jiahui Li et al.
Metronidazole (MTZ) is a widely used nitroimidazole antibiotic, and its excessive use may pose health risks. Thus, establishing a rapid and sensitive MTZ detection method is of great practical significance. In this work, nitrogen-doped carb...
A high-performance nanohybrid impedimetric platform for early cancer detection via c-Myc oncoprotein sensing [0.03%]
一种高性能纳杂化阻抗平台通过c-Myc癌基因蛋白检测进行早期癌症检测
Diptirekha Mohanta,Urmila Saxena
Diptirekha Mohanta
Widespread and precise detection of oncogenic biomarkers is critical for timely cancer diagnosis and effective treatment. The Myc oncogene is widely deregulated across multiple malignancies, turning it a compelling target for pan-cancer det...
A zwitterionic-enabled one-pot electrochemical strategy for stable end-point detection of isothermal nucleic acid amplification [0.03%]
一种用于等温核酸扩增末端稳定检测的 zwittemionic（两性离子）使能的一锅式电化学生物传感策略
Yijie Wang,Yang Li,Jiufa Zhang et al.
Yijie Wang et al.
Indicator-based electrochemical loop-mediated isothermal amplification (EC-LAMP) is highly attractive for portable nucleic acid testing, yet its practical deployment is fundamentally constrained by severe signal instability caused by amplif...