A FRET-based NCA fluorescent probe for highly sensitive and selective detection of hydrogen sulfide [0.03%]
一种用于检测硫化氢的FRET型NCA荧光探针
Lingxiao Xiong,Xin Liu,Wanmeng Li et al.
Lingxiao Xiong et al.
A Förster resonance energy transfer (FRET)-based fluorescent probe (NCA) was developed for highly sensitive and selective detection of hydrogen sulfide (H2S). In this design, coumarin (CA) serves as the fluorescent donor and nitrobenzoxadi...
Rapid quality assessment of organic fertilizers using fused FTIR and LIBS spectroscopy with machine learning [0.03%]
基于FTIR和LIBS融合光谱及机器学习的有机肥料快速鉴别与品质评价方法研究
Xuebin Xu,Fei Ma,Jianmin Zhou et al.
Xuebin Xu et al.
Organic fertilizers are vital for sustainable agriculture, but conventional quality assessment methods are often time-consuming and costly. This study developed a rapid analytical framework by synergistically combining Fourier transform inf...
The effect of shungite pretreatment on quantitative extraction of metals [0.03%]
改性舒金石柱富集提取水体中痕量金属的研究
Irina V Minenkova,Victoria V Voronkova,Daniil I Yarykin et al.
Irina V Minenkova et al.
One of the most interesting natural materials with a rich composition of various elements, including rare earth elements, is shungite. Inductively coupled plasma mass spectrometry (ICP-MS) was successfully used to detect metals in various o...
Data independent acquisition mass spectrometry (DIA-MS) in cancer studies: a concise review [0.03%]
数据独立采集质谱(DIA-MS)在癌症研究中的应用综述
Bharath S Kumar
Bharath S Kumar
Advances in proteomics are reshaping our understanding of cancer biology by enabling the direct quantification of proteins and their modifications in complex biological systems. Among emerging mass spectrometry techniques, Data-Independent ...
A streamlined technique for in-depth ubiquitomics analysis of formalin-fixed paraffin-embedded tissues [0.03%]
一种针对福尔马林固定石蜡包埋组织的深入泛素组分析的技术方法
Shifang Liang,Bo Zheng,Dongying Huang et al.
Shifang Liang et al.
Formalin-fixed paraffin-embedded (FFPE) tissues offer advantages over fresh frozen (FrFr) tissues in terms of preserving tissue integrity, reducing long-term storage costs, and increasing sample availability, thus providing an invaluable re...
Joy Solomon,Akeem Sanni,Waziha Purba et al.
Joy Solomon et al.
Glycosylation is a highly complex and functionally diverse post-translational modification that modulates protein folding, stability, cell signaling, and immune response. Aberrant glycosylation is associated with numerous diseases, includin...
A label-free fluorescence assay for microRNAs based on linear enzymatic signal amplification [0.03%]
一种基于线性酶促信号放大的无标签荧光微RNA检测方法
Avinash Kumar,Jing Qu,Yi-Ming Liu et al.
Avinash Kumar et al.
MicroRNAs (miRNAs) are regulators in various physiological and pathological processes with significant potential for disease diagnosis and therapeutic monitoring. However, their quantification remains a challenge due to their high degradabi...
Gold nanoparticle aptasensor synergizing colorimetric and Tyndall effect signals for ultrasensitive ATP detection [0.03%]
一种金纳米粒子适配子传感器结合显色和丁达尔效应信号用于超灵敏地检测ATP
Ruizheng Hao,Shipei Cheng,Yingsong Guo et al.
Ruizheng Hao et al.
Conventional ATP detection methods (e.g., fluorescence and electrochemistry) face significant sensitivity constraints, while colorimetric approaches-despite offering visual simplicity-remain inadequate for clinical applications due to limit...
Effects of Dynabead type, surface chemistry, and incubation on agglomerate behavior in dual-phase microfluidic systems [0.03%]
Dynabead类型、表面化学和孵育对双相微流控系统聚集行为的影响
Abdul Basit Zia,Ian G Foulds
Abdul Basit Zia
This study investigates the agglomeration behavior of streptavidin-coated Dynabeads (M270, C1, and T1) with different sizes (2.8 µm and 1.05 µm) and surface chemistries (hydrophilic and hydrophobic) when incubated with biotinylated bovine...
Rapid and sensitive detection of circulating tumor DNA via a CRISPR/Cas12a-based catalytic hairpin assembly [0.03%]
基于CRISPR/Cas12a的催化发卡组装技术快速灵敏地检测循环肿瘤DNA
Songbai Tian,Lingzi Yao,Feng Gong et al.
Songbai Tian et al.
Cancer is one of the major diseases that endanger the human health. Circulating tumor DNA (ctDNA) is an ideal biomarker for the real-time monitoring of cancer. In the present work, a rapid and sensitive assay coupled with CRISPR/Cas12a and ...