Surgical Management of Pleomorphic Lung Carcinoma With Left Atrial Invasion: Two Cases Including One With Cerebral Artery Metastasis [0.03%]
多形性肺癌伴左心耳侵犯的外科治疗——含一例脑动脉转移患者
Eitetsu Koh,Yasuo Sekine,Hiroyuki Saitou et al.
Eitetsu Koh et al.
Pleomorphic carcinoma is a rare, aggressive subtype of non-small cell lung cancer (NSCLC). Invasion into the left atrium and dissemination to cerebral arteries are exceptionally uncommon, and the role of cardiopulmonary bypass (CPB)-assiste...
Case Reports
Thoracic cancer. 2026 Jan;17(1):e70199. DOI:10.1111/1759-7714.70199 2026
Neoadjuvant Glucocorticoids Facilitate Resection in Advanced B-Type Thymomas: A Propensity-Matched Analysis of Surgical and Survival Outcomes [0.03%]
新辅助糖皮质激素可促进B型纵隔胸腺癌外科手术切除：倾向匹配的手术及生存结局分析
Zhen Yu,Xintao Yu,Jian Cui et al.
Zhen Yu et al.
Background: Locally advanced B-type thymomas frequently present technical challenges for R0 resection. Given the limitations of conventional neoadjuvant therapies, this study investigated glucocorticoids (GCs) as a potent...
Peripheral Immune Cell Profiles as Predictive Biomarkers of Immune Checkpoint Inhibitor Efficacy in Elderly Patients With Advanced Non-Small Cell Lung Cancer [0.03%]
外周免疫细胞谱型作为老年晚期非小细胞肺癌患者免疫检查点抑制剂疗效的预测性生物标志物
Shouzheng Wang,Yilin Wang,Xi Li et al.
Shouzheng Wang et al.
Background: Immune checkpoint inhibitors (ICIs) significantly impact advanced non-small cell lung cancer (NSCLC) management, but predictive biomarkers for elderly patients remain controversial. This study aimed to assess ...
Observational Study
Thoracic cancer. 2025 Dec;16(24):e70202. DOI:10.1111/1759-7714.70202 2025
Kaiyin Shi,Amin Li
Kaiyin Shi
The KRAS G12D mutation is a highly prevalent oncogenic driver in pancreatic ductal adenocarcinoma, colorectal cancer, and non-small cell lung cancer. Unlike other KRAS variants, G12D lacks a reactive site; therefore, it is considered "undru...
Diagnostic Value of Photon-Counting CT in Pericardial Metastases: A Single-Center Retrospective Study [0.03%]
光子计数CT在心包转移瘤诊断中的价值：单中心回顾性研究
Hui Wang,Yuqin Jin,Yuangang Qi et al.
Hui Wang et al.
Pericardial metastases are common in advanced cancers but often remain undetected due to subtle symptoms. Photon-counting CT (PCT) offers improved spatial resolution and contrast-to-noise ratio (CNR) compared with conventional CT (CCT), pot...
Factors Influencing the Effectiveness of Fluorescence in Determining the Intersegmental Plane During Intentional Pulmonary Segmentectomy: Results of a Prospective Study on 196 Patients [0.03%]
荧光在有意肺段切除中确定节段平面有效性的多因素分析：196例行手术患者的前瞻性研究结果
Quentin Rudondy,Florian Martinet-Kosinski,Tayeb Benkiran et al.
Quentin Rudondy et al.
Background: Intentional pulmonary segmentectomy via minimally invasive surgery is now commonly used to treat early stage non-small cell lung cancers smaller than 2 cm. The main challenge of this procedure lies in identify...
Impact of Craniocaudal Tumor Dimension and the Ninth Edition of the TNM Stage Classification on Prognosis in Resected Thymoma [0.03%]
头颈径肿瘤大小及肿瘤分期系统第9版对完全切除胸腺瘤预后的影响分析
Dai Okazaki,Natsuo Tomita,Katsuhiro Okuda et al.
Dai Okazaki et al.
Background: Thymoma is a rare thymic epithelial tumor, and its prognostic factors remain not fully elucidated. This study aimed to identify simple, practical preoperative predictors of prognosis, focusing on tumor dimensi...
Predictive Value of the Estimated Dose of Radiation to Immune Cells Versus Conventional Parameters in Elderly Patients With Unresectable Stage III NSCLC: A Two-Center Real-World Study [0.03%]
老年不可切除III期NSCLC患者中免疫细胞辐射剂量的预测价值与传统参数的真实世界研究：来自两个中心的研究
Huan Li,Xingyu Du,Song Guan et al.
Huan Li et al.
Objective: To compare the predictive value of the estimated dose of radiation to immune cells (EDRIC) with conventional dosimetric parameters for survival in elderly patients with stage III unresectable NSCLC after chemoi...
Multicenter Study
Thoracic cancer. 2025 Dec;16(24):e70196. DOI:10.1111/1759-7714.70196 2025
Somatic Mutations of Thymic Epithelial Tumors Identified in the Prospective THYMOGENE Trial [0.03%]
THYMOGENE前瞻性试验鉴定胸腺上皮肿瘤体细胞突变
Eleonora Pardini,Federico Cucchiara,Serena Barachini et al.
Eleonora Pardini et al.
Background: The molecular landscape of thymic epithelial tumors has been partially elucidated. GTF2I mutation drives the pathogenesis in approximately 50% of tumors; however, the key molecular aberrations in the other cas...
Salvage Surgery Following Systemic Therapy in Initially Unresectable Non-Small Cell Lung Cancer [0.03%]
新辅助治疗后转化为可切除的非小细胞肺癌患者的手术治療
Katsutoshi Seto,Yoshitsugu Horio,Katsuhiro Masago et al.
Katsutoshi Seto et al.
Background: This study evaluated the safety, long-term survival, and prognostic factors associated with salvage pulmonary surgery following systemic therapy for initially unresectable non-small cell lung cancer (NSCLC). ...